Results 31 to 40 of about 1,829,235 (358)
International Journal of Infectious DiseasesIntroduction: The rising prevalence of drug-resistant infections presents a challenge to modern medicine by limiting life-saving therapeutic options, especially for those who cannot afford more expensive second-and third-line antibiotics, and ...
Dr Elloise Du Toit +3 more
doaj +1 more source
Microorganisms, 2021 Using whole-genome sequencing and cloning of the target gene, we identified blaOXA-900 carbapenemase, a novel blaOXA belonging to a distant and distinct sub-family of blaOXA-48-like. The plasmid-mediated gene was identified in a C.
Sammy Frenk +9 more
doaj +1 more source
Discovery of the fourth mobile sulfonamide resistance gene
Microbiome, 2017 Background Over the past 75 years, human pathogens have acquired antibiotic resistance genes (ARGs), often from environmental bacteria. Integrons play a major role in the acquisition of antibiotic resistance genes.
Mohammad Razavi +5 more
doaj +1 more source
Antibiotics, 2023 Beta-lactam resistance can lead to increased mortality, higher healthcare expenses, and limited therapeutic options. The primary mechanism of beta-lactam resistance is the production of extended-spectrum beta-lactamases (ESBL) and AmpC beta-lactamases ...
Hadas Kon +7 more
doaj +1 more source
Medical Clinics of North America, 2001 Pseudomonas aeruginosa is responsible for a variety of nosocomial infections associated with high morbidity and mortality, involving the immunocompromised and immunocompetent host. There are several groups of antipseudomonal antibiotics available today: antipseudomonal penicillins (carboxy and ureido penicillins), antipseudomonal cephalosporins ...
Giamarellou, H, Antoniadou, A
openaire +3 more sources
Two pandemics: the COVID-19 pandemic’s impact on future AMR collaboration in Europe
Humanities & Social Sciences Communications, 2023 Based on 117 responses to a web survey in 29 European countries and interviews with bureaucrats in managerial positions, this paper investigates how people working professionally with antimicrobial resistance (AMR) assess the impact of the COVID-19 ...
Elina Lampi +3 more
doaj +1 more source
An evaluation of antimicrobial stewardship in community pharmacy [PDF]
, 2015 This study investigated several aspects of antimicrobial stewardship by gathering information from community pharmacists and members of the public. The aim was to identify how community pharmacists implement antimicrobial stewardship guidelines and ...
Hancock, Laura Jade, Mellor, Callan
core +1 more source
Journal of Clinical MicrobiologyWith the increase in antimicrobial resistance and multidrug-resistant infections, the discovery of additional therapeutic options to combat different infection types and treat different patient populations is paramount.
O. N. Walser +6 more
doaj +1 more source
Impact and Sustainability of Antibiotic Stewardship on Antibiotic Prescribing in Visceral Surgery
Antibiotics, 2021 Background: Antibiotic stewardship (AS) ward rounds are a core element in clinical care for surgical patients. Therefore, we aimed to analyze the impact of surgical AS ward rounds on antibiotic prescribing, and the sustainability of the effect after the ...
Magdalena Monika Gruber +4 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács +8 more
wiley +1 more source