Results 31 to 40 of about 1,234,048 (260)

The role of microbiology and pharmacy departments in the stewardship of antibiotic prescribing in European hospitals [PDF]

, 2007
This observational, cross-sectional study describes the role played by clinical microbiology and pharmacy departments in the stewardship of antibiotic prescribing in European hospitals.
Mollison, Jill, Krcmery, Vladimir, van der Meer, Jos W.M., Gould, I.M., Bruce, Julie, MacKenzie, Fiona, Monnet, Dominique L., Cookson, Barry   +7 more
core   +1 more source

Carbapenem-Resistant Klebsiella pneumoniae Exhibiting Clinically Undetected Colistin Heteroresistance Leads to Treatment Failure in a Murine Model of Infection

mBio, 2018
Antibiotic resistance is a growing crisis and a grave threat to human health. It is projected that antibiotic-resistant infections will lead to 10 million annual deaths worldwide by the year 2050.
Victor I. Band, Sarah W. Satola, Eileen M. Burd, Monica M. Farley, Jesse T. Jacob, David S. Weiss   +5 more
doaj   +1 more source

Antibiotic resistance in the environment, with particular reference to MRSA [PDF]

, 2008
The introduction of β-lactam antibiotics (penicillins and cephalosporins) in the 1940s and 1950s probably represents the most dramatic event in the battle against infection in human medicine.
William Gaze, Gaze, William H., Hawkey, Peter, Peter Hawkey, Hawkey, P. M., O'Neill, Colette, O'Neill, C, Colette O'Neill, Elizabeth Wellington, Gaze, W, Wellington, E, Wellington, Elizabeth, Wellington, E. M. H., Gaze, William   +13 more
core   +1 more source

Acinetobacter baumannii Bloodstream Infections: A Nationwide Study in Israel

Microorganisms, 2023
Acinetobacter baumannii (Ab) bloodstream infections (BSIs) are a major public health concern and associated with high mortality. We describe the nationwide incidence, antimicrobial resistance, and mortality of Ab-BSI in Israel using laboratory-based BSI ...
Amir Nutman, Elizabeth Temkin, Liat Wullfhart, Vered Schechner, Mitchell J. Schwaber, Yehuda Carmeli   +5 more
doaj   +1 more source

Vaccines in the fight against antimicrobial resistance – from evidence to policy - perspectives from South Africa

International Journal of Infectious Diseases
Introduction: The rising prevalence of drug-resistant infections presents a challenge to modern medicine by limiting life-saving therapeutic options, especially for those who cannot afford more expensive second-and third-line antibiotics, and ...
Dr Elloise Du Toit, Dr Erta Kalanxhi, Prof Adrian Brink, Ms Isabella Impalli   +3 more
doaj   +1 more source

Occurrence, Typing, and Resistance Genes of ESBL/AmpC-Producing Enterobacterales in Fresh Vegetables Purchased in Central Israel

Antibiotics, 2023
Beta-lactam resistance can lead to increased mortality, higher healthcare expenses, and limited therapeutic options. The primary mechanism of beta-lactam resistance is the production of extended-spectrum beta-lactamases (ESBL) and AmpC beta-lactamases ...
Hadas Kon, Mor Lurie-Weinberger, Adi Cohen, Liat Metsamber, Alona Keren-Paz, David Schwartz, Yehuda Carmeli, Vered Schechner   +7 more
doaj   +1 more source

A new approach for the discovery of antibiotics by targeting non-multiplying bacteria: a novel topical antibiotic for staphylococcal infections. [PDF]

, 2010
In a clinical infection, multiplying and non-multiplying bacteria co-exist. Antibiotics kill multiplying bacteria, but they are very inefficient at killing non-multipliers which leads to slow or partial death of the total target population of microbes in
Liu, Y, Alireza Shamaei-Tousi, Coates Anthony, Shamaei-Tousi, A, Hu, Y, Liu Yingjun, Yanmin Hu, Hu Yanmin, Yingjun Liu, Shamaei-Tousi Alireza, Anthony Coates, Coates, A   +11 more
core   +2 more sources

Heterogeneity in the response to the metabolic environment drives fosfomycin heteroresistance

Nature Communications
Heteroresistance is a form of antibiotic resistance in which a phenotypically unstable subpopulation of resistant cells coexists with a majority susceptible population.
Jacob E. Choby, David A. Hufnagel, Muqing Ma, Tugba Ozturk, Victor I. Band, Minsu Kim, David S. Weiss   +6 more
doaj   +1 more source

OXA-900, a Novel OXA Sub-Family Carbapenemase Identified in Citrobacter freundii, Evades Detection by Commercial Molecular Diagnostics Tests

Microorganisms, 2021
Using whole-genome sequencing and cloning of the target gene, we identified blaOXA-900 carbapenemase, a novel blaOXA belonging to a distant and distinct sub-family of blaOXA-48-like. The plasmid-mediated gene was identified in a C.
Sammy Frenk, Nadya Rakovitsky, Hadas Kon, Reut Rov, Shirin Abramov, Mor Nadia Lurie-Weinberger, David Schwartz, Erica Pinco, Jonathan Lellouche, Yehuda Carmeli   +9 more
doaj   +1 more source

Solid Pseudopapillary Neoplasm of the Pancreas in Children and Adolescents: Expert Recommendations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Solid pseudopapillary neoplasm of the pancreas (SPN) is a rare low‐grade malignant exocrine pancreatic tumor, mostly discovered during the second decade of life in females, with a very good prognosis, provided microscopically complete surgical excision is achieved.
Sabine Irtan, Michael Abele, Calogero Virgone, Michaela Kuhlen, Ricardo Lopez‐Almarez, Tal Ben‐Ami, Ewa Bien, Maja Cesen, Malgorzata A. Krawczyk, Andrea Ferrari, Gianni Bisogno, Yves Reguerre, Dominik T. Schneider, Louise Galmiche, Jorg Fuchs, Sarah Braungart, Bilgehan Yalcin, Ines B. Brecht, Daniel Orbach   +18 more
wiley   +1 more source