Results 1 to 10 of about 19,820 (248)

Exploring the Potential Influence of the Human Gut Microbiota on the Gut Resistome: A Systematic Review

Microbiology Research
Antibiotic resistance is a global health problem. The human gut microbiome is implicated in the dynamics of antibiotic resistance acquisition and transmission, with the gut microbiota thought to play a crucial role.
Justine Fri, Pascal O Bessong
exaly   +4 more sources

Breastfeeding and the milk resistome shape the establishment and transmission of antibiotic resistance genes in the infant gut microbiome [PDF]

Gut Microbes
The infant resistome, the collection of antibiotic resistance genes (ARGs) of newborns, is critical for gut microbiota establishment. Using metagenomic sequencing data, we analyzed various 1-week and 1-month postpartum samples to study infant resistome ...
Conor Feehily, Fionnuala M. McAuliffe, Paul Cotter   +2 more
exaly   +5 more sources

Inflammatory Endotype-Associated Airway Resistome in Chronic Obstructive Pulmonary Disease [PDF]

Microbiology Spectrum, 2022
Antimicrobial resistance is a global concern in chronic respiratory diseases, including chronic obstructive pulmonary disease (COPD). The collection of antibiotic resistance genes or resistome in human airways may underlie the resistance.
Xinzhu Yi, Yanjun Li, Haiyue Liu, Xiaomin Liu, Junhao Yang, Jingyuan Gao, Yuqiong Yang, Zhenyu Liang, Fengyan Wang, Dandan Chen, Lingwei Wang, Weijuan Shi, David C. L. Lam, Martin R. Stampfli, Paul W. Jones, Rongchang Chen, Zhang Wang   +16 more
doaj   +2 more sources

Population-based variations of a core resistome revealed by urban sewage metagenome surveillance

Environment International, 2022
Sewage-based surveillance is widely employed to understand the occurrence and distribution of antimicrobial resistance (AMR) in urban community. However, there are limited studies which investigated the sewage of different sources within community.
Yiliang He, Feijian Mao, Kalisvar Marimuthu   +2 more
exaly   +3 more sources

Human Gut Antibiotic Resistome and Progression of Diabetes

Advanced Science, 2022
The antibiotic resistance crisis underlies globally increasing failures in treating deadly bacterial infections, largely due to the selection of antibiotic resistance genes (ARG) collection, known as the resistome, in human gut microbiota. So far, little
Ju-Sheng Zheng, Lai-Bao Zhuo, Zengliang Jiang   +2 more
exaly   +2 more sources

Environmental drivers of the resistome across the Baltic Sea

Microbiome
Background Antimicrobial resistance is a major global health concern, with the environment playing a key role in its emergence and spread. Understanding the relationships between environmental factors, microbial communities, and resistance mechanisms is ...
Malte Posselt, Elias Broman, Benoit Dessirier   +2 more
exaly   +2 more sources

Presence of high-risk ARGs with greater diversity and abundance in the rare resistome in wastewater across China

Journal of Hazardous Materials
Antibiotic resistance genes (ARGs) are widely recognized as hazardous materials that pose risks to public health. The core resistome, with its low ARG diversity yet accounting for the majority of the total ARG abundance, dominating the profile of ...
Xiqing Li, Chaoqi Chen
exaly   +2 more sources

Metagenomics reveals the temporal dynamics of the rumen resistome and microbiome in goat kids

Microbiome
Background The gut microbiome of domestic animals carries antibiotic resistance genes (ARGs) which can be transmitted to the environment and humans, resulting in challenges of antibiotic resistance. Although it has been reported that the rumen microbiome
Jianmin Chai, Yimin Zhuang, Kai Cui, Yanliang Bi, Naifeng Zhang   +4 more
doaj   +2 more sources

CARD 2023: expanded curation, support for machine learning, and resistome prediction at the Comprehensive Antibiotic Resistance Database

Nucleic Acids Res., 2022
The Comprehensive Antibiotic Resistance Database (CARD; card.mcmaster.ca) combines the Antibiotic Resistance Ontology (ARO) with curated AMR gene (ARG) sequences and resistance-conferring mutations to provide an informatics framework for annotation and ...
Brian P. Alcock, W. Huynh, Romeo Chalil, Keaton W. Smith, A. Raphenya, Mateusz A. Wlodarski, Arman Edalatmand, A. Petkau, S. Syed, Kara K. Tsang, Sheridan J. C. Baker, Mugdha Dave, Madeline C. McCarthy, Karyn M. Mukiri, Jalees A. Nasir, Bahar Golbon, Hamna Imtiaz, Xingjian Jiang, Komal Kaur, Megan Kwong, Zi-Cheng Liang, Ke Niu, Prabakar Shan, Jasmine Y. J. Yang, Kristen L. Gray, Gemma Hoad, Baofeng Jia, Timsy Bhando, L. Carfrae, Maya A. Farha, S. French, R. Gordzevich, K. Rachwalski, Megan M. Tu, E. Bordeleau, Damion M. Dooley, E. Griffiths, Haley L. Zubyk, E. Brown, F. Maguire, R. Beiko, W. Hsiao, F. Brinkman, G. Van Domselaar, A. McArthur   +44 more
semanticscholar   +1 more source

Colistin-degrading proteases confer collective resistance to microbial communities during polymicrobial infections

Microbiome, 2022
Background The increasing prevalence of resistance against the last-resort antibiotic colistin is a significant threat to global public health. Here, we discovered a novel colistin resistance mechanism via enzymatic inactivation of the drug and proposed ...
Do-Hoon Lee, Ju-Hee Cha, Dae-Wi Kim, Kihyun Lee, Yong-Seok Kim, Hyo-Young Oh, You-Hee Cho, Chang-Jun Cha   +7 more
doaj   +1 more source