Description and determinants of the faecal resistome and microbiome of farmers and slaughterhouse workers: A metagenome-wide cross-sectional study [PDF]
Background: By studying the entire human faecal resistome and associated microbiome, the diversity and abundance of faecal antimicrobial resistance genes (ARGs) can be comprehensively characterized.
Liese Van Gompel +20 more
doaj +2 more sources
Nasal Resistome Development in Infants With Cystic Fibrosis in the First Year of Life [PDF]
Polymicrobial infections of the respiratory tract due to antibiotic resistant bacteria are a great concern in patients with cystic fibrosis (CF). We therefore aimed at establishing a functional metagenomic method to analyze the nasal resistome in infants
Aurélie Allemann +14 more
doaj +3 more sources
Long-term spatiotemporal dynamics of β-lactamase resistome in the Han River, South Korea [PDF]
The global dissemination of antimicrobial resistance, particularly resistance to widely prescribed β-lactam antibiotics, is a critical public health threat worldwide.
Do-Hoon Lee +4 more
doaj +2 more sources
Metagenomic Characterisation of Antibiotic Resistance in Anaerobic Digesters and Their Implications for Environmental Health. [PDF]
Anaerobic digester metagenomes revealed diverse resistance‐associated annotations and antibiotic target loci, highlighting their potential role in environmental AMR surveillance. The findings emphasise the need for cautious interpretation of resistome profiles and further host‐resolved analyses to determine the mobility and clinical relevance of ...
Olasupo OA +12 more
europepmc +2 more sources
Subclinical Mastitis and Antibiotic Exposure Reshape the Milk Bacteriome, Resistome, and Metabolic Functional Profiles in Dairy Cows [PDF]
Overview of the study workflow and metagenomic analysis of bovine milk bacteriomes. Milk samples were collected from dairy cows and classified into three health‐status groups: subclinical mastitis (SCM), antibiotic‐treated (ANT) SCM cows, and healthy milk (HM). Samples were further stratified according to dairy cow breeds (Holstein Friesian Cross; HFC,
Hoque M +5 more
europepmc +2 more sources
Pooled Shotgun Metagenomics Reveals Cloacal Microbiota Composition and Resistome Patterns in Chickens from Kazakhstan [PDF]
Monitoring poultry microbiota and antimicrobial resistance genes is important, as they can reflect flock health, farm conditions, and the level of antimicrobial resistance.
Ilya Korotetskiy +8 more
doaj +2 more sources
The European livestock resistome
Metagenomic sequencing has proven to be a powerful tool in the monitoring of antimicrobial resistance (AMR). Here, we provide a comparative analysis of the resistome from pigs, poultry, veal calves, turkey, and rainbow trout, for a total of 538 herds ...
P. Munk +16 more
semanticscholar +8 more sources
The influence of the phylum Planctomycetota in the environmental resistome.
Antimicrobial resistance is one of the leading causes of death worldwide and research on this topic has been on the spotlight for a long time. More recently and in agreement with the One Health Approach, the focus has moved towards the environmental ...
O. Godinho +3 more
semanticscholar +4 more sources
Insights into the dynamics of antibiotic resistance genes in the human gut microbiome across populations [PDF]
The human microbiome serves as a reservoir of antibiotic resistance genes (ARGs), collectively known as the resistome, which has crucial implications for human health.
Deepika Pateriya +2 more
doaj +2 more sources
The gut resistome as a potential determinant of immunotherapy response: antibiotics, immunometabolism, and precision oncology [PDF]
Immune checkpoint inhibitors (ICIs) have transformed cancer therapy, yet their efficacy can be compromised by systemic antibiotic exposure and the resulting disruption of the gut microbiome.
Min-Kyung Joo +6 more
doaj +2 more sources

