Nasal Resistome Development in Infants With Cystic Fibrosis in the First Year of Life [PDF]
Frontiers in Microbiology, 2019 Polymicrobial infections of the respiratory tract due to antibiotic resistant bacteria are a great concern in patients with cystic fibrosis (CF). We therefore aimed at establishing a functional metagenomic method to analyze the nasal resistome in infants
Aurélie Allemann +14 more
doaj +2 more sources
Antibiotic resistance in chronic respiratory diseases: from susceptibility testing to the resistome
European Respiratory Review, 2022 The development of resistome analysis, i.e. the comprehensive analysis of antibiotic-resistance genes (ARGs), is enabling a better understanding of the mechanisms of antibiotic-resistance emergence. The respiratory microbiome is a dynamic and interactive
Hélène Pailhoriès +6 more
doaj +2 more sources
Early-life development of the microbiome and resistome in antibiotic-naïve dairy calves [PDF]
Microbiology SpectrumThis study aimed to characterize early-life changes in the fecal microbiome and resistome of calves. Fecal samples were collected from 49 Holstein heifers born and raised at a large organic dairy in Texas without antimicrobial drug exposures.
Maggie M. Murphy +6 more
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Transient restructuring of the active oral resistome during probiotic Streptococcus salivarius K12 colonization in a 3D polymicrobial biofilm model [PDF]
Journal of Oral MicrobiologyBackground The oral cavity harbours a complex and transcriptionally active antibiotic resistance gene (ARG) reservoir shaped by polymicrobial biofilm ecology.
Nadeeka S. Udawatte +7 more
doaj +2 more sources
Description and determinants of the faecal resistome and microbiome of farmers and slaughterhouse workers: A metagenome-wide cross-sectional study [PDF]
Environment International, 2020 Background: By studying the entire human faecal resistome and associated microbiome, the diversity and abundance of faecal antimicrobial resistance genes (ARGs) can be comprehensively characterized.
Liese Van Gompel +20 more
doaj +2 more sources
Bacteriophages limitedly contribute to the antimicrobial resistome of microbial communities in wastewater treatment plants [PDF]
Microbiology Spectrum, 2023 Bacteriophages are known as players in the transmission of antimicrobial resistance genes (ARGs) by horizontal gene transfer. In this study, we characterized the bacteriophage community and the associated ARGs to estimate the potential for phages to ...
Raffaella Sabatino +5 more
doaj +2 more sources
Microbiology ResearchAntibiotic resistance is a global health problem. The human gut microbiome is implicated in the dynamics of antibiotic resistance acquisition and transmission, with the gut microbiota thought to play a crucial role.
Justine Fri +3 more
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Microbiome, 2017 Background Shotgun metagenomic sequencing is increasingly utilized as a tool to evaluate ecological-level dynamics of antimicrobial resistance and virulence, in conjunction with microbiome analysis.
Noelle R. Noyes +14 more
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Gut resistome of NSCLC patients treated with immunotherapy [PDF]
Frontiers in GeneticsBackgroundThe newest method of treatment for patients with NSCLC (non-small cell lung cancer) is immunotherapy directed at the immune checkpoints PD-1 (Programmed Cell Death 1) and PD-L1 (Programmed Cell Death Ligand 1).
Ewelina Iwan +11 more
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Gut resistome linked to sexual preference and HIV infection [PDF]
BMC MicrobiologyBackground People living with HIV (PLWH) are at increased risk of acquisition of multidrug resistant organisms due to higher rates of predisposing factors.
Elisa Rubio Garcia +5 more
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