Results 11 to 20 of about 11,688 (211)

Inflammatory Endotype-Associated Airway Resistome in Chronic Obstructive Pulmonary Disease [PDF]

Microbiology Spectrum, 2022
Antimicrobial resistance is a global concern in chronic respiratory diseases, including chronic obstructive pulmonary disease (COPD). The collection of antibiotic resistance genes or resistome in human airways may underlie the resistance.
Xinzhu Yi, Yanjun Li, Haiyue Liu, Xiaomin Liu, Junhao Yang, Jingyuan Gao, Yuqiong Yang, Zhenyu Liang, Fengyan Wang, Dandan Chen, Lingwei Wang, Weijuan Shi, David C. L. Lam, Martin R. Stampfli, Paul W. Jones, Rongchang Chen, Zhang Wang   +16 more
doaj   +2 more sources

Metagenomics analysis of the neonatal intestinal resistome [PDF]

Frontiers in Pediatrics, 2023
IntroductionThe intestinal microbiome forms a major reservoir for antibiotic resistance genes (ARGs). Little is known about the neonatal intestinal resistome.ObjectiveThe objective of this study was to investigate the intestinal resistome and factors that influence the abundance of ARGs in a large cohort of neonates.MethodsShotgun metagenomics was used
Stefano Leo, Stefano Leo, Omer F. Cetiner, Laure F. Pittet, Laure F. Pittet, Laure F. Pittet, Nicole L. Messina, Nicole L. Messina, William Jakob, Laurent Falquet, Nigel Curtis, Nigel Curtis, Nigel Curtis, Petra Zimmermann, Petra Zimmermann, Petra Zimmermann, Petra Zimmermann   +16 more
core   +5 more sources

The European livestock resistome [PDF]

mSystems
ABSTRACT Metagenomic sequencing has proven to be a powerful tool in the monitoring of antimicrobial resistance (AMR). Here, we provide a comparative analysis of the resistome from pigs, poultry, veal calves, turkey, and rainbow trout, for a total of 538 herds across nine European countries.
Patrick Munk, Dongsheng Yang, Timo Röder, Leonie Maier, Thomas Nordahl Petersen, Ana Sofia Ribeiro Duarte, Philip T. L. C. Clausen, Christian Brinch, Liese Van Gompel, Roosmarijn Luiken, Jaap A. Wagenaar, Heike Schmitt, Dick J. J. Heederik, Dik J. Mevius, Lidwien A. M. Smit, Alex Bossers, Frank M. Aarestrup, Haitske Graveland, Bruno Gonzalez-Zorn, Gabriel Moyano, Pascal Sanders, Claire Chauvin, Antonio Battisti, Jeroen Dewulf, Katharina Wadepohl, Dariusz Wasyl, Magdalena Skarzyńska, Magdalena Zajac, Agnieszka Pękala-Safińska, Hristo Daskalov, Katharina D. C. Stärk   +30 more
core   +9 more sources

Mining the Antibiotic Resistome

Chemistry & Biology, 2012
Antibiotic-producing microoganisms are a reservoir of drug resistance genes. Studies of the "antibiotic resistome" can inform antimicrobial drug discovery and explain the emergence of multidrug resistant pathogens. In this issue of Chemistry & Biology, Westman and colleagues take an alternative look at the resistome and identify genes that could be ...
Sello, Jason K.
openaire   +3 more sources

Antibiotic resistome in groundwater and its association with mountain springs and river [PDF]

Ecotoxicology and Environmental Safety, 2023
The distribution of antibiotic resistance genes (ARGs) in water sources potentially threatens drinking water safety. However, the sources of antibiotic resistome in groundwater are still under-investigated.
Fu-Yi Huang, Yi Zhao, Roy Neilson, Xin-Yuan Zhou, Hu Li, Lei Ding, Shu-Yi-Dan Zhou, Jian-Qiang Su   +7 more
doaj   +2 more sources

Population-based variations of a core resistome revealed by urban sewage metagenome surveillance

Environment International, 2022
Sewage-based surveillance is widely employed to understand the occurrence and distribution of antimicrobial resistance (AMR) in urban community. However, there are limited studies which investigated the sewage of different sources within community.
Wenxuan Li, Feijian Mao, Charmaine Ng
exaly   +3 more sources

Human Gut Antibiotic Resistome and Progression of Diabetes

Advanced Science, 2022
The antibiotic resistance crisis underlies globally increasing failures in treating deadly bacterial infections, largely due to the selection of antibiotic resistance genes (ARG) collection, known as the resistome, in human gut microbiota. So far, little
Menglei Shuai, Fang-Fang Zeng, Yuanqing Fu   +2 more
exaly   +2 more sources

Resistome expansion in disease-associated human gut microbiomes

Microbiome, 2023
Background The resistome, the collection of antibiotic resistance genes (ARGs) in a microbiome, is increasingly recognised as relevant to the development of clinically relevant antibiotic resistance.
Simen Fredriksen, Stef de Warle, Peter van Baarlen, Jos Boekhorst, Jerry M. Wells   +4 more
doaj   +2 more sources

Mobile resistome of human gut and pathogen drives anthropogenic bloom of antibiotic resistance [PDF]

Microbiome, 2020
Background The impact of human activities on the environmental resistome has been documented in many studies, but there remains the controversial question of whether the increased antibiotic resistance observed in anthropogenically impacted environments ...
Kihyun Lee, Dae-Wi Kim, Do-Hoon Lee, Yong-Seok Kim, Ji-Hye Bu, Ju-Hee Cha, Cung Nawl Thawng, Eun-Mi Hwang, Hoon Je Seong, Woo Jun Sul, Elizabeth M. H. Wellington, Christopher Quince, Chang-Jun Cha   +12 more
doaj   +2 more sources

The challenges of defining the human nasopharyngeal resistome [PDF]

Trends in Microbiology, 2023
The nasopharynx is an important microbial reservoir for the emergence and spread of antibiotic-resistant organisms. The nasopharyngeal resistome is an extensive, adaptable reservoir of antibiotic-resistance genes (ARGs) within this niche. Metagenomic sequencing decodes the genetic material of all organisms within a sample using next-generation ...
O'Connor, L, Heyderman, R
openaire   +4 more sources