Results 101 to 110 of about 251,321 (315)

Beyond Antimicrobial Resistance: Evidence for a Distinct Role of the AcrD Efflux Pump in Salmonella Biology

mBio, 2016
For over 20 years, bacterial multidrug resistance (MDR) efflux pumps have been studied because of their impact on resistance to antimicrobials. However, critical questions remain, including why produce efflux pumps under non-antimicrobial treatment ...
Michelle M. C. Buckner, Jessica M. A. Blair, Roberto M. La Ragione, Jane Newcombe, Daniel J. Dwyer, Alasdair Ivens, Laura J. V. Piddock   +6 more
doaj   +1 more source

Aetiology, Antimicrobial Susceptibility and Predictors of\ud Urinary Tract Infection among Febrile Under-Fives at\ud Muhimbili National Hospital, Dar es Salaam-Tanzania [PDF]

, 2013
Urinary tract infection (UTI) is a common cause of fever in children and contributes to morbidity and mortality. This study aimed at determining prevalence, aetiology and antimicrobial susceptibility pattern of the isolates at Muhimbili National Hospital
Fataki, Maulidi, Francis, Joel M., Fredrick, Francis, Maselle, Samuel Y.   +3 more
core  

Antimicrobials: a global alliance for optimizing their rational use in intra-abdominal infections (AGORA) [PDF]

, 2016
Intra-abdominal infections (IAI) are an important cause of morbidity and are frequently associated with poor prognosis, particularly in high-risk patients.
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core   +4 more sources

Antimicrobial Drugs [PDF]

Anesthesia Progress, 2013
Abstract Antibiotics play a vital role in dental practice for managing orofacial infections. They are used to manage existing infection and they are also used as prophylaxis for certain medical conditions and surgical procedures. This article will review pharmacological and therapeutic considerations for the proper use of these agents for ...
openaire   +2 more sources

SiO2‐CaOCME/Poly(Tetrahydrofuran)/Poly(Caprolactone) 3D‐Printed Scaffolds Drive Human‐Bone Marrow Stromal Cell Osteogenic Differentiation

Advanced Healthcare Materials, EarlyView.
3D printed hybrid scaffolds combining bioactive silica–calcium chemistry with elastic polymers guide human bone stem cells to form bone. The scaffolds support cell survival, organization, and invasion while releasing osteogenic ions. Together, architecture and composition drive bone‐specific gene expression, extracellular matrix organization, and ...
David R. Sory, Agathe C.M. Heyraud, Julian R. Jones, Sara M. Rankin   +3 more
wiley   +1 more source

Evolution of social contacts patterns in France over the SARS-CoV-2 pandemic: results from the SocialCov survey

BMC Infectious Diseases
Background Non-pharmaceutical measures such as lockdowns, curfews and place closures were implemented in France during 2020–2022 to reduce contacts in the population, to limit the spread of SARS-CoV-2 and reduce COVID-19 healthcare burden.
Flora Soussand, Armiya Youssouf Abdou, Marie Sanchez, Bich-Tram Huynh, Coralie Giese, Cécile Tran-Kiem, Guillaume Béraud, Didier Guillemot, Simon Cauchemez, Lulla Opatowski, Paolo Bosetti   +10 more
doaj   +1 more source

Oral Candida Colonisation in Radiotherapy-Treated Head and Neck Cancer Patients: Prevalence, Species Diversity and Antifungal Resistance Compared with Healthy Controls

Targets
Head and neck cancer (HNC) patients frequently experience alterations in the oral environment following radiotherapy, including xerostomia and impaired mucosal integrity, which may favour fungal overgrowth.
Tanya Pereira-Riveros, Alicia Lozano Borbalas, Eric Fernández-De la Cruz, Josep M. Sierra, Teresa Vinuesa   +4 more
doaj   +1 more source

Dual‐Peptide Nanoplatform: Mesoporous Silica Nanoparticles Functionalized With a Cell‐Penetrating Peptide and Loaded With Rationally Designed Antimicrobial Peptides for Tuberculosis Therapy

Advanced Healthcare Materials, EarlyView.
Machine learning–guided engineering of a plectasin‐derived peptide yields DC05, a potent antimycobacterial candidate. Encapsulation into tuftsin‐functionalized mesoporous silica nanoparticles enhances intracellular delivery, stability, and activity against Mycobacterium tuberculosis while maintaining low cytotoxicity and minimal hemolysis. The combined
Christian S. Carnero Canales, Cesar Augusto Roque‐Borda, Ana Carolina Cerqueira Negri, Oswaldo Ramirez Delgado, Letícia Oliveira Catarin Nunes, Flávia Aparecida Resende, Hernane Barud, Norival Alves Santos‐Filho, Saulo Santesso Garrido, Karen Cristina Oliveira, Alexandra Ivo de Medeiros, Rafael Miguel Sábio, Fernando Rogério Pavan   +12 more
wiley   +1 more source

Antimicrobials [PDF]

Nature Biotechnology, 2020
openaire   +2 more sources

A Long‐Lived Human Neurovascular PENTA Culture Model Captures Incomplete Vascular Repair and Glia‐Associated Signaling After Traumatic Brain Injury

Advanced Healthcare Materials, EarlyView.
A long‐lived, five‐cell‐type human neurovascular (PENTA) model recreates vascular disorganization and incomplete repair after traumatic brain injury (TBI). By integrating endothelial, glial, neuronal, and immune components within a 3D scaffold, the platform enables time‐resolved analysis of neurovascular remodeling and provides a human‐relevant system ...
Daniel S. Hinrichsen, Sunghyun Jun, Colleen M. Arrasmith, Charitha C. Anamala, Mitchell D. Thielen, Anapaula Garcia, Volha Liaudanskaya   +6 more
wiley   +1 more source