Results 141 to 150 of about 6,678 (215)
Treatment of cutaneous leishmaniasis with antimony sodium gluconate
Leishmaniasis, while uncommon in the United States, is found frequently in other parts of the world. We present a case of cutaneous leishmaniasis and describe diagnosis, clinical and histological characteristics, and treatment. Report of a Case A 45-year-old man vacationed with his wife on the Yucatan Peninsula in Mexico in March 1975.
W. A. Koerber
semanticscholar +5 more sources
In a prospective study conducted in Mymensingh district of Bangladesh, 1, 273 patients were assessed for the presence of visceral leishmaniasis (VL). Sodium antimony gluconate (SAG) was successfully administered to 715 patients with parasitologically confirmed infection.
Somenath Roy Chowdhury +4 more
semanticscholar +4 more sources
Parasitologically confirmed cases of post-kala-azar dermal leishmaniasis (PKDL) were treated by infusion with amphotericin B deoxycholate (ABD; 1 mg/kg.day on days 1-20, 21-40 and 61-80) or by intramuscular injection with sodium antimony gluconate (SAG; 20-day courses at 20 mg/kg day, with 20-day, drug-free intervals). Of the 11 patients given ABD, all
C.P. Thakur
semanticscholar +6 more sources
(1947). Observations on the use of Sodium Antimony Gluconate (Sodium Stibogluconate) in the Treatment of Kala-Azar. Annals of Tropical Medicine & Parasitology: Vol. 41, No. 1, pp. 14-21.
Robert Kirk, Mohammed Hamad Sati
semanticscholar +4 more sources
In a study to evaluate the relative efficacies of sodium antimony gluconate (SAG) and amphotericin B (AMB), each drug was used to treat 60 Indian cases of visceral leishmaniasis (VL). At the time of treatment, each case had recently been parasitologically confirmed.
C.P. Thakur, Shyam Narayan
semanticscholar +4 more sources
Since there are very few affordable antileishmanial drugs available, antimonial resistance has crippled antileishmanial therapy, thereby emphasising the need for development of novel therapeutic strategies. This study aimed to evaluate the antileishmanial role of combined therapy with sodium antimony gluconate (SAG) and the triterpenoid glycyrrhizic ...
Amrita Bhattacharjee +7 more
semanticscholar +4 more sources
In India, sodium antimony gluconate is the drug of choice for kala-azar. Due to increasing unresponsiveness to this drug in the current epidemic that began in the early 1970s, daily doses of 20 mg/kg/day for 30 days or more is recommended as opposed to the 10 mg/kg/day dose for 6-10 days used in the past. Of the 130-150 patients treated annually at our
Shyam Sundar +7 more
semanticscholar +4 more sources
Reason for post-kala-azar dermal leishmaniasis (PKDL) is yet to be established. Earlier it was observed that morphology and biochemical properties of host peroxisomes were impaired during Leishmania infection. As peroxisome is known to be involved in various metabolic pathways to monitor normal function of the host cells, it is essential that ...
Shreedhara Gupta +2 more
semanticscholar +4 more sources
Thirty-two parasitologically confirmed visceral leishmanisis (VL) patients and 23 healthy, age- and gender-matched controls were recruited between April 2001 and March 2002 and studied for intracellular cytokine production after stimulation in vitro using a Fluorescence Activated Cell Sorter-based intracellular cytokine assay.
C.P. Thakur +2 more
semanticscholar +4 more sources

