Multifaceted Population Structure and Reproductive Strategy in Leishmania donovani Complex in One Sudanese Village [PDF]
PLoS Neglected Tropical Diseases, 2011 Leishmania species of the subgenus Leishmania and especially L. donovani are responsible for a large proportion of visceral leishmaniasis cases. The debate on the mode of reproduction and population structure of Leishmania parasites remains opened.
Alain Dessein +2 more
exaly +2 more sources
Vaccine Development Against Leishmania donovani [PDF]
Frontiers in Immunology, 2012 La leishmaniasis visceral (VL) causada por Leishmania donovani y Leishmania infantum/chagasi representa la segunda enfermedad infecciosa más difícil en todo el mundo, lo que lleva a casi 500.000 nuevos casos y 60.000 muertes al año. La VL zoonótica causada por L.
Nahid Ali, Amrita Das, Ali Nahid
exaly +4 more sources
Detection of Leishmania donovani Status in Dogs (Canis familiaris, Linnaeus, 1758) in the Karamoja Subregion of Uganda [PDF]
Journal of Tropical MedicineTo date, the reservoir host for visceral leishmaniasis, a neglected tropical disease caused by Leishmania donovani, is unknown, although studies pointing to dogs, domestic animals, and rodents are emerging.
Charles D. Kato +12 more
doaj +2 more sources
Sphingosine-1-phosphate receptor signaling regulates an ERK1/2–p65 molecular switch in macrophages during Leishmania donovani infection [PDF]
Frontiers in PharmacologyLeishmania donovani establishes intracellular infection by suppressing macrophage inflammatory responses. Although sphingosine-1-phosphate (S1P) signaling is known to regulate macrophage function, the receptor isotype–specific mechanisms involved during ...
Mohd Arish, Mohd Arish, Farha Naz
doaj +2 more sources
In vitro antipromastigote activity of decoction and hydrodistillation extracts of Clematis hirsuta leaves against Leishmania donovani and Leishmania aethiopica [PDF]
BMC Complementary Medicine and TherapiesLeishmaniasis remains a significant health concern in four eco-epidemiological regions of the world (WHO, 2024). Annually, there are thought to be 700,000 to 1 million new cases of leishmaniasis.
Etsegenet Abebe +10 more
doaj +2 more sources
Targeting Ergosterol Biosynthesis in Leishmania donovani: Essentiality of Sterol 14alpha-demethylase [PDF]
PLoS Neglected Tropical Diseases, 2015 Leishmania protozoan parasites (Trypanosomatidae family) are the causative agents of cutaneous, mucocutaneous and visceral leishmaniasis worldwide. While these diseases are associated with significant morbidity and mortality, there are few adequate ...
Junyong Choi +2 more
exaly +2 more sources
Direct sequencing of Leishmania donovani from patients in Garissa County, Northern Kenya, reveals a newly emerging intra-specific hybrid genotype. [PDF]
PLoS Neglected Tropical DiseasesIntroductionLeishmaniasis is endemic in many countries, and in Kenya outbreaks of visceral leishmaniasis (VL) commonly occur in Garissa, Isiolo, Marsabit, Turkana, and Wajir.
Vane Kwamboka Omwenga +10 more
doaj +2 more sources
Evaluation of CD1a immunostaining in the diagnosis of cutaneous leishmaniasis caused by Leishmania donovani in Sri Lanka [PDF]
ParasitologyCutaneous leishmaniasis (CL) is a vector-borne parasitic disease, routinely diagnosed by direct light microscopy. The sensitivity of this method is dependent on the number of parasites present in the lesion.
Hasna Riyal +4 more
doaj +2 more sources
Emerging Leishmania donovani Lineages Associated with Cutaneous Leishmaniasis, Himachal Pradesh, India, 2023 [PDF]
Emerging Infectious DiseasesThe clinical manifestation of leishmaniasis has historically been determined by the Leishmania species involved. However, recent emergence of novel Leishmania lineages has caused atypical pathologies.
Patrick Lypaczewski +7 more
doaj +2 more sources
Leishmania donovani: an unusual eyelid presentation. [PDF]
Eye (Lond)Rubegni G, Lamberti A, Tosi GM.
europepmc +3 more sources