Results 1 to 10 of about 13,658 (180)

Detection of Leishmania donovani Status in Dogs (Canis familiaris, Linnaeus, 1758) in the Karamoja Subregion of Uganda [PDF]

Journal of Tropical Medicine
To date, the reservoir host for visceral leishmaniasis, a neglected tropical disease caused by Leishmania donovani, is unknown, although studies pointing to dogs, domestic animals, and rodents are emerging.
Charles D. Kato, Angella Musewa, Tequiero A. Okumu, Margaret Mbuchi, Edwinah Atusingwize, Ivan Ankunda, Santiago C. Tomas, Gloria Pol Ferrer, Benard Matovu, Emmanuel Muhumuza, Marta Planellas Bachs, Jesus Muro Figueres, James Robert Ochieng   +12 more
doaj   +2 more sources

Sphingosine-1-phosphate receptor signaling regulates an ERK1/2–p65 molecular switch in macrophages during Leishmania donovani infection [PDF]

Frontiers in Pharmacology
Leishmania donovani establishes intracellular infection by suppressing macrophage inflammatory responses. Although sphingosine-1-phosphate (S1P) signaling is known to regulate macrophage function, the receptor isotype–specific mechanisms involved during ...
Mohd Arish, Mohd Arish, Farha Naz
doaj   +2 more sources

In vitro antipromastigote activity of decoction and hydrodistillation extracts of Clematis hirsuta leaves against Leishmania donovani and Leishmania aethiopica [PDF]

BMC Complementary Medicine and Therapies
Leishmaniasis remains a significant health concern in four eco-epidemiological regions of the world (WHO, 2024). Annually, there are thought to be 700,000 to 1 million new cases of leishmaniasis.
Etsegenet Abebe, Tegenu Gelana, Helen Nigussie, Abebe Ejigu, Yehenew Asmamaw, Dawit Araya, Werissaw Hailesilassie, Markos Tadele, Betelhem Sirak, Solomon Mequanente, Gurja Belay   +10 more
doaj   +2 more sources

Targeting Ergosterol Biosynthesis in Leishmania donovani: Essentiality of Sterol 14alpha-demethylase [PDF]

PLoS Neglected Tropical Diseases, 2015
Leishmania protozoan parasites (Trypanosomatidae family) are the causative agents of cutaneous, mucocutaneous and visceral leishmaniasis worldwide. While these diseases are associated with significant morbidity and mortality, there are few adequate ...
Laura-Isobel Mccall, Jun Yong Choi, Geraldine De Muylder   +2 more
exaly   +2 more sources

Evaluation of CD1a immunostaining in the diagnosis of cutaneous leishmaniasis caused by Leishmania donovani in Sri Lanka [PDF]

Parasitology
Cutaneous leishmaniasis (CL) is a vector-borne parasitic disease, routinely diagnosed by direct light microscopy. The sensitivity of this method is dependent on the number of parasites present in the lesion.
Hasna Riyal, Nilakshi Samaranayake, Priyani Amarathunga, Deepani Munidasa, Nadira Karunaweera   +4 more
doaj   +2 more sources

Direct sequencing of Leishmania donovani from patients in Garissa County, Northern Kenya, reveals a newly emerging intra-specific hybrid genotype. [PDF]

PLoS Neglected Tropical Diseases
IntroductionLeishmaniasis is endemic in many countries, and in Kenya outbreaks of visceral leishmaniasis (VL) commonly occur in Garissa, Isiolo, Marsabit, Turkana, and Wajir.
Vane Kwamboka Omwenga, Gathii Kimita, Damaris Matoke-Muhia, Cyrus Ayieko, Clement Masakhwe, Mohamed Hussein Ibrahim, Senne Heeren, Jean-Claude Dujardin, Pieter Monsieurs, Malgorzata Anna Domagalska, John Waitumbi   +10 more
doaj   +2 more sources

Emerging Leishmania donovani Lineages Associated with Cutaneous Leishmaniasis, Himachal Pradesh, India, 2023 [PDF]

Emerging Infectious Diseases
The clinical manifestation of leishmaniasis has historically been determined by the Leishmania species involved. However, recent emergence of novel Leishmania lineages has caused atypical pathologies.
Patrick Lypaczewski, Yogesh Chauhan, Kayla Paulini, Lovlesh Thakur, Shailja Chauhan, Ezrah Isaac Roy, Greg Matlashewski, Manju Jain   +7 more
doaj   +2 more sources

Leishmania donovani Transmission Cycle Associated with Human Infection, Phlebotomus alexandri Sand Flies, and Hare Blood Meals, Israel

Emerging Infectious Diseases, 2023
Cutaneous leishmaniasis caused by Leishmania major or L. tropica and visceral leishmaniasis caused by L. infantum have been reported in Israel. We collected Phlebotomus spp.
Liora Studentsky, Laor Orshan, Fouad Akad, Irina Ben Avi, Debora Diaz, Shirly Elbaz, Orly Sagi, Gal Zagron, Lea Valinsky, Maya Davidovich-Cohen, Gad Baneth   +10 more
doaj   +1 more source

Leishmania donovani: an unusual eyelid presentation. [PDF]

Eye (Lond)
Rubegni G, Lamberti A, Tosi GM.
europepmc   +3 more sources

Genetic diversity analysis of Chinese Leishmania isolates and development of L. donovani complex-specific markers by RAPD

BMC Infectious Diseases, 2021
Background Leishmaniasis is one of the most neglected tropical diseases in the world and remains endemic in some underdeveloped regions, including western China.
Dongmei Yuan, Hanxiao Qin, Dali Chen, Jianping Chen   +3 more
doaj   +1 more source