Results 31 to 40 of about 65,283 (218)

Postoperative Late-Onset Endophthalmitis Caused by Leishmania donovani: A Case Report

Case Reports in Ophthalmology, 2018
Leishmania donovani is a human blood parasite that belongs to the genus Leishmania. We would like to present a case of late Leishmania donovani endophthalmitis in one eye of a patient that underwent simultaneous bilateral grade 3 cataract surgery.
Bojan Kozomara, Ernesta Potkonjak, Ratimir Lazic, Sanja Savicic, Nikica Gabric   +4 more
doaj   +1 more source

Modulation of Aneuploidy in Leishmania donovani during Adaptation to Different In Vitro and In Vivo Environments and Its Impact on Gene Expression

mBio, 2017
Aneuploidy is usually deleterious in multicellular organisms but appears to be tolerated and potentially beneficial in unicellular organisms, including pathogens. Leishmania, a major protozoan parasite, is emerging as a new model for aneuploidy, since in
F. Dumetz, H. Imamura, M. Sanders, V. Seblova, J. Myskova, P. Pescher, M. Vanaerschot, C. Meehan, B. Cuypers, G. De Muylder, G. F. Späth, G. Bussotti, J. Vermeesch, M. Berriman, J. Cotton, P. Volf, J. Dujardin, M. A. Domagalska   +17 more
semanticscholar   +1 more source

Exposure to Leishmania spp. and sand flies in domestic animals in northwestern Ethiopia

Parasites & Vectors, 2015
Background Human visceral leishmaniasis caused by Leishmania donovani is considered an anthroponosis; however, Leishmania-infected animals have been increasingly reported in L.
Iva Rohousova, Dalit Talmi-Frank, Tatiana Kostalova, Nikola Polanska, Tereza Lestinova, Aysheshm Kassahun, Daniel Yasur-Landau, Carla Maia, Roni King, Jan Votypka, Charles L. Jaffe, Alon Warburg, Asrat Hailu, Petr Volf, Gad Baneth   +14 more
doaj   +1 more source

The in vitro leishmanicidal activity of hexadecylphosphocholine (miltefosine) against four medically relevant Leishmania species of Brazil

Memorias do Instituto Oswaldo Cruz, 2011
The in vitro leishmanicidal activity of miltefosine® (Zentaris GmbH) was assessed against four medically relevant Leishmania species of Brazil: Leishmania (Leishmania) amazonensis, Leishmania (Viannia) braziliensis, Leishmania (Viannia) guyanensis and ...
Eliane de Morais-Teixeira, Quesia Souza Damasceno, Mariana Kolos Galuppo, Alvaro José Romanha, Ana Rabello   +4 more
doaj   +1 more source

Leishmania donovani Exploits Tunneling Nanotubes for Dissemination and Propagation of B Cell Activation

Microbiology Spectrum, 2023
Polyclonal B cell activation and the resulting hypergammaglobulinemia are a detrimental consequence of visceral leishmaniasis (VL); however, the mechanisms underlying this excessive production of nonprotective antibodies are still poorly understood. Here,
Tanja Stögerer, Sasha Silva-Barrios, Liseth Carmona-Pérez, Sharada Swaminathan, Linh Thuy Mai, Louis-Philippe Leroux, Maritza Jaramillo, Albert Descoteaux, Simona Stäger   +8 more
doaj   +1 more source

Prevalence of Leishmania species among patients with cutaneous leishmaniasis in Qassim province of Saudi Arabia

BMC Public Health, 2019
Background Leishmaniasis is a parasitic infection endemic in more than ninety countries of the world. The cutaneous leishmaniasis (CL) is a most common form of leishmaniasis and it remains to be a major public health issue in Saudi Arabia. This study was
Zafar Rasheed, Ahmed A. Ahmed, Tarek Salem, Mohammed S. Al-Dhubaibi, Ahmad A. Al Robaee, Abdullateef A. Alzolibani   +5 more
doaj   +1 more source

Molecular Preadaptation to Antimony Resistance in Leishmania donovani on the Indian Subcontinent

Msphere, 2018
The “antibiotic resistance crisis” is a major challenge for scientists and medical professionals. This steady rise in drug-resistant pathogens also extends to parasitic diseases, with antimony being the first anti-Leishmania drug that fell in the Indian ...
F. Dumetz, B. Cuypers, H. Imamura, D. Zander, E. D'Haenens, I. Maes, M. A. Domagalska, J. Clos, J. Dujardin, G. De Muylder   +9 more
semanticscholar   +1 more source

Characterisation of the Leishmania donovani/L. infantum Hybrid Isolated from an Autochothonous Kala-Azar Patient: Preliminary Results of an In Vivo Model

Türkiye Parazitoloji Dergisi, 2021
Objective:In the present study, preliminary outcomes of the in vivo assessment of a Leishmania donovani/L. infantum hybrid isolated from a hospitalised patient with visceral leishmaniasis in Manisa and identified through analysis of the Leishmania ...
Özgür Kurt, Nesteren Mansur Özen, Elif Merve Aydın, Deniz Ece Kaya, Cavit Kerem Kayhan, Sinem Öktem Okullu, Ümit İnce, Fadile Yıldız Zeyrek   +7 more
doaj   +1 more source

Homologous minicircles in Leishmania donovani

Transactions of the Royal Society of Tropical Medicine and Hygiene, 2002
Leishmania minicircular deoxyribonucleic acid (DNA) is arranged into different classes according to sequence. These classes differ substantially in sequence, despite species- and genus-specific regions, and are present in widely different copy numbers within and between Leishmania strains.
Lambson, B., Barker, D.C.
openaire   +3 more sources

Guanylate Binding Proteins Restrict Leishmania donovani Growth in Nonphagocytic Cells Independent of Parasitophorous Vacuolar Targeting

mBio, 2020
Interferon (IFN)-inducible guanylate binding proteins (GBPs) play important roles in host defense against many intracellular pathogens that reside within pathogen-containing vacuoles (PVs).
Arun Kumar Haldar, Utsav Nigam, Masahiro Yamamoto, Jörn Coers, Neena Goyal   +4 more
doaj   +1 more source