Results 11 to 20 of about 13,658 (180)

Multifaceted population structure and reproductive strategy in Leishmania donovani complex in one Sudanese village. [PDF]

open access: yesPLoS Neglected Tropical Diseases, 2011
Leishmania species of the subgenus Leishmania and especially L. donovani are responsible for a large proportion of visceral leishmaniasis cases. The debate on the mode of reproduction and population structure of Leishmania parasites remains opened.
Virginie Rougeron   +8 more
doaj   +1 more source

LEISHMANIA DONOVANI IN THE PERIPHERAL BLOOD [PDF]

open access: yesJournal of Experimental Medicine, 1923
1. The effect of human red cells and serum on the growth of Leishmania donovani has been studied and a blood culture method devised, based on these findings. 2. The distribution of blood platelets and of the different varieties of leucocytes in the strata of centrifugalized diluted blood has been investigated, and also the distribution ...
C W, Young, H M, Van Sant
openaire   +2 more sources

HAT2 mediates histone H4K4 acetylation and affects micrococcal nuclease sensitivity of chromatin in Leishmania donovani. [PDF]

open access: yesPLoS ONE, 2017
Histone post-translational modifications (PTMs) such as acetylation and methylation are known to affect chromatin higher order structures. Primary targets of these modifications include basic residues present at N-terminus tail region of core histones ...
Pravin K Jha   +4 more
doaj   +1 more source

Vaccine Development Against Leishmania donovani [PDF]

open access: yesFrontiers in Immunology, 2012
La leishmaniasis visceral (VL) causada por Leishmania donovani y Leishmania infantum/chagasi representa la segunda enfermedad infecciosa más difícil en todo el mundo, lo que lleva a casi 500.000 nuevos casos y 60.000 muertes al año. La VL zoonótica causada por L.
Amrita Das, Nahid Ali
openaire   +3 more sources

Comprehensive proteomic analysis of autophagosomes derived from Leishmania-infected macrophages.

open access: yesPLoS ONE, 2023
Recently, autophagy has been implicated as a host defense mechanism against intracellular pathogens. On the other hand, certain intracellular pathogens such as Leishmania can manipulate the host's autophagy to promote their survival.
Devki Nandan   +5 more
doaj   +1 more source

Retinoic Acid Increases Cellular Cholesterol in Leishmania donovani-Infected Macrophages in an mTOR-Independent Manner

open access: yesMicrobiology Spectrum, 2022
Infection with Leishmania donovani reduces cellular cholesterol and thus deprives the host cells by inhibiting its synthesis and uptake. Changes in cholesterol levels increase the chance of attachment and internalization of L. donovani in macrophages (Mϕ)
Satya Prakash, Ambak Kumar Rai
doaj   +1 more source

Postoperative Late-Onset Endophthalmitis Caused by Leishmania donovani: A Case Report

open access: yesCase Reports in Ophthalmology, 2018
Leishmania donovani is a human blood parasite that belongs to the genus Leishmania. We would like to present a case of late Leishmania donovani endophthalmitis in one eye of a patient that underwent simultaneous bilateral grade 3 cataract surgery.
Bojan Kozomara   +4 more
doaj   +1 more source

Exposure to Leishmania spp. and sand flies in domestic animals in northwestern Ethiopia

open access: yesParasites & Vectors, 2015
Background Human visceral leishmaniasis caused by Leishmania donovani is considered an anthroponosis; however, Leishmania-infected animals have been increasingly reported in L.
Iva Rohousova   +14 more
doaj   +1 more source

The in vitro leishmanicidal activity of hexadecylphosphocholine (miltefosine) against four medically relevant Leishmania species of Brazil

open access: yesMemorias do Instituto Oswaldo Cruz, 2011
The in vitro leishmanicidal activity of miltefosine® (Zentaris GmbH) was assessed against four medically relevant Leishmania species of Brazil: Leishmania (Leishmania) amazonensis, Leishmania (Viannia) braziliensis, Leishmania (Viannia) guyanensis and ...
Eliane de Morais-Teixeira   +4 more
doaj   +1 more source

Leishmania donovani Exploits Tunneling Nanotubes for Dissemination and Propagation of B Cell Activation

open access: yesMicrobiology Spectrum, 2023
Polyclonal B cell activation and the resulting hypergammaglobulinemia are a detrimental consequence of visceral leishmaniasis (VL); however, the mechanisms underlying this excessive production of nonprotective antibodies are still poorly understood. Here,
Tanja Stögerer   +8 more
doaj   +1 more source

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