Carbon Dioxide Assimilation by Leishmania donovani [PDF]
Nature, 1960 WHILE studying the glucose metabolism of Leishmania donovani, the protozoan organism causing visceral leishmaniasis, it has been found that cell suspensions of this organism in a saline-bicarbonate buffer containing glucose can assimilate, a measurable amount of carbon dioxide along with the formation of different acidic end products1.
A N, CHATTERJEE, J J, GHOSH
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Targeting Ergosterol biosynthesis in Leishmania donovani: essentiality of sterol 14 alpha-demethylase. [PDF]
PLoS Neglected Tropical Diseases, 2015 Leishmania protozoan parasites (Trypanosomatidae family) are the causative agents of cutaneous, mucocutaneous and visceral leishmaniasis worldwide. While these diseases are associated with significant morbidity and mortality, there are few adequate ...
Laura-Isobel McCall +11 more
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Leishmania donovani: an unusual eyelid presentation. [PDF]
Eye (Lond)Rubegni G, Lamberti A, Tosi GM.
europepmc +3 more sources
Multifaceted population structure and reproductive strategy in Leishmania donovani complex in one Sudanese village. [PDF]
PLoS Neglected Tropical Diseases, 2011 Leishmania species of the subgenus Leishmania and especially L. donovani are responsible for a large proportion of visceral leishmaniasis cases. The debate on the mode of reproduction and population structure of Leishmania parasites remains opened.
Virginie Rougeron +8 more
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HAT2 mediates histone H4K4 acetylation and affects micrococcal nuclease sensitivity of chromatin in Leishmania donovani. [PDF]
PLoS ONE, 2017 Histone post-translational modifications (PTMs) such as acetylation and methylation are known to affect chromatin higher order structures. Primary targets of these modifications include basic residues present at N-terminus tail region of core histones ...
Pravin K Jha +4 more
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Synthesis and Antileishmanial Activity of 1,2,4,5-Tetraoxanes against Leishmania donovani [PDF]
, 2020 A chemically diverse range of novel tetraoxanes was synthesized and evaluated in vitro against intramacrophage amastigote forms of Leishmania donovani. All 15 tested tetraoxanes displayed activity, with IC50 values ranging from 2 to 45 µm.
Amado, Patrícia +5 more
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Intra- and interspecific polymorphisms ofLeishmania donovani andL. tropica minicircle DNA [PDF]
, 1994 A pair of degenerate polymerase chain reaction (PCR) primers (LEI-1, TCG GAT CC[C,T] [G,C]TG GGT AGG GGC GT; LEI-2, ACG GAT CC[G,C] [G,C][A,C]C TAT [A,T]TT ACA CC) defining a 0.15-kb segment ofLeishmania minicircle DNA was constructed.
AJ Magill +16 more
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LEISHMANIA DONOVANI IN THE PERIPHERAL BLOOD [PDF]
Journal of Experimental Medicine, 1923 1. The effect of human red cells and serum on the growth of Leishmania donovani has been studied and a blood culture method devised, based on these findings. 2. The distribution of blood platelets and of the different varieties of leucocytes in the strata of centrifugalized diluted blood has been investigated, and also the distribution ...
C W, Young, H M, Van Sant
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Leishmania donovani populations in Eastern Sudan: temporal structuring and a link between human and canine transmission. [PDF]
, 2014 BACKGROUND: Visceral leishmaniasis (VL), caused by the members of the Leishmania donovani complex, has been responsible for devastating VL epidemics in the Sudan.
Baleela, Rania +6 more
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Comprehensive proteomic analysis of autophagosomes derived from Leishmania-infected macrophages.
PLoS ONE, 2023 Recently, autophagy has been implicated as a host defense mechanism against intracellular pathogens. On the other hand, certain intracellular pathogens such as Leishmania can manipulate the host's autophagy to promote their survival.
Devki Nandan +5 more
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