Results 11 to 20 of about 65,283 (218)
Targeting Ergosterol Biosynthesis in Leishmania donovani: Essentiality of Sterol 14alpha-demethylase [PDF]
PLoS Neglected Tropical Diseases, 2015 Leishmania protozoan parasites (Trypanosomatidae family) are the causative agents of cutaneous, mucocutaneous and visceral leishmaniasis worldwide. While these diseases are associated with significant morbidity and mortality, there are few adequate ...
Junyong Choi +2 more
exaly +3 more sources
Definitions, 2020 CROSS-REACTION: Antiserum to Leishmania: It cross-reacts with tissue sections containing Sarcocystis cysts from cattle and intravascular stages of Sarcocystis of a raccoon. It does not crossreact with Toxoplasma o Neospora caninum.
semanticscholar +2 more sources
Frontiers in Immunology, 2021 Visceral leishmaniasis (VL) is a fatal parasitic disease if untreated. Treatment options of VL diminish due to emerging drug resistance. Although the principal host cells for the multiplication of Leishmania are macrophages, neutrophils are the first ...
Mareike Ohms +8 more
doaj +2 more sources
In vitro activity and mode of action of phenolic compounds on Leishmania donovani
PLoS Neglected Tropical Diseases, 2019 Background Leishmaniasis is a disease caused by the protozoan parasite, Leishmania. The disease remains a global threat to public health requiring effective chemotherapy for control and treatment.
Cynthia Amisigo +2 more
exaly +2 more sources
Vaccine Development Against Leishmania donovani [PDF]
Frontiers in Immunology, 2012 La leishmaniasis visceral (VL) causada por Leishmania donovani y Leishmania infantum/chagasi representa la segunda enfermedad infecciosa más difícil en todo el mundo, lo que lleva a casi 500.000 nuevos casos y 60.000 muertes al año. La VL zoonótica causada por L.
Nahid Ali, Amrita Das
exaly +4 more sources
Multifaceted Population Structure and Reproductive Strategy in Leishmania donovani Complex in One Sudanese Village [PDF]
PLoS Neglected Tropical Diseases, 2011 Leishmania species of the subgenus Leishmania and especially L. donovani are responsible for a large proportion of visceral leishmaniasis cases. The debate on the mode of reproduction and population structure of Leishmania parasites remains opened.
Virginie Rougeron +2 more
exaly +2 more sources
Global genome diversity of the Leishmania donovani complex
eLife, 2020 Protozoan parasites of the Leishmania donovani complex – L. donovani and L. infantum – cause the fatal disease visceral leishmaniasis. We present the first comprehensive genome-wide global study, with 151 cultured field isolates representing most of the ...
Susanne U Franssen +20 more
doaj +2 more sources
L-Asparaginase of Leishmania donovani: Metabolic target and its role in Amphotericin B resistance
International Journal for Parasitology: Drugs and Drug Resistance, 2017 Emergence of Amphotericin B (AmB) resistant Leishmania donovani has posed major therapeutic challenge against the parasite. Consequently, combination therapy aimed at multiple molecular targets, based on proteome wise network analysis has been ...
Jasdeep Singh +7 more
doaj +2 more sources
BMC Infectious Diseases, 2017 Background Leishmania donovani is the etiological agent of visceral leishmaniasis (VL) in the Indian subcontinent. However, it is also known to cause cutaneous leishmaniasis (CL) in Sri Lanka. Sri Lankan L. donovani differs from other L. donovani strains,
Udeshika Lakmini Kariyawasam +13 more
doaj +2 more sources
Detection of Leishmania donovani Status in Dogs (Canis familiaris, Linnaeus, 1758) in the Karamoja Subregion of Uganda [PDF]
Journal of Tropical MedicineTo date, the reservoir host for visceral leishmaniasis, a neglected tropical disease caused by Leishmania donovani, is unknown, although studies pointing to dogs, domestic animals, and rodents are emerging.
Charles D. Kato +12 more
doaj +2 more sources