Results 11 to 20 of about 69,891 (211)

Detection of Leishmania donovani Status in Dogs (Canis familiaris, Linnaeus, 1758) in the Karamoja Subregion of Uganda [PDF]

Journal of Tropical Medicine
To date, the reservoir host for visceral leishmaniasis, a neglected tropical disease caused by Leishmania donovani, is unknown, although studies pointing to dogs, domestic animals, and rodents are emerging.
Charles D. Kato, Angella Musewa, Tequiero A. Okumu, Margaret Mbuchi, Edwinah Atusingwize, Ivan Ankunda, Santiago C. Tomas, Gloria Pol Ferrer, Benard Matovu, Emmanuel Muhumuza, Marta Planellas Bachs, Jesus Muro Figueres, James Robert Ochieng   +12 more
doaj   +2 more sources

In vitro antipromastigote activity of decoction and hydrodistillation extracts of Clematis hirsuta leaves against Leishmania donovani and Leishmania aethiopica [PDF]

BMC Complementary Medicine and Therapies
Leishmaniasis remains a significant health concern in four eco-epidemiological regions of the world (WHO, 2024). Annually, there are thought to be 700,000 to 1 million new cases of leishmaniasis.
Etsegenet Abebe, Tegenu Gelana, Helen Nigussie, Abebe Ejigu, Yehenew Asmamaw, Dawit Araya, Werissaw Hailesilassie, Markos Tadele, Betelhem Sirak, Solomon Mequanente, Gurja Belay   +10 more
doaj   +2 more sources

Sphingosine-1-phosphate receptor signaling regulates an ERK1/2–p65 molecular switch in macrophages during Leishmania donovani infection [PDF]

Frontiers in Pharmacology
Leishmania donovani establishes intracellular infection by suppressing macrophage inflammatory responses. Although sphingosine-1-phosphate (S1P) signaling is known to regulate macrophage function, the receptor isotype–specific mechanisms involved during ...
Mohd Arish, Mohd Arish, Farha Naz
doaj   +2 more sources

Direct sequencing of Leishmania donovani from patients in Garissa County, Northern Kenya, reveals a newly emerging intra-specific hybrid genotype. [PDF]

PLoS Neglected Tropical Diseases
IntroductionLeishmaniasis is endemic in many countries, and in Kenya outbreaks of visceral leishmaniasis (VL) commonly occur in Garissa, Isiolo, Marsabit, Turkana, and Wajir.
Vane Kwamboka Omwenga, Gathii Kimita, Damaris Matoke-Muhia, Cyrus Ayieko, Clement Masakhwe, Mohamed Hussein Ibrahim, Senne Heeren, Jean-Claude Dujardin, Pieter Monsieurs, Malgorzata Anna Domagalska, John Waitumbi   +10 more
doaj   +2 more sources

Leishmania donovani is the only cause of visceral leishmaniasis in East Africa; previous descriptions of L. infantum and "L. archibaldi" from this region are a consequence of convergent evolution in the isoenzyme data [PDF]

, 2004
Isoenzyme-based studies have identified 3 taxa/species/'phylogenetic complexes' as agents of visceral leishmaniasis in Sudan: L. donovani, L. infantum and "L. archibaldi". However, these observations remain controversial.
Watts, P C, Noyes, H A, Kemp, S J, Jamjoom, M B, Ashford, R W, Bates, P A, Chance, M L   +6 more
core   +6 more sources

Metabolic variation during development in culture of Leishmania donovani promastigotes [PDF]

, 2011
The genome sequencing of several Leishmania species has provided immense amounts of data and allowed the prediction of the metabolic pathways potentially operating.
Cordeiro-da-Silva, Anabela, Coombs, Graham H, Silva, Ana Marta, Ana Marta Silva, Anabela Cordeiro-da-Silva, Silva Ana Marta, Coombs Graham H., Cordeiro-da-Silva Anabela, Graham H Coombs   +8 more
core   +5 more sources

Leishmania donovani: an unusual eyelid presentation. [PDF]

Eye (Lond)
Rubegni G, Lamberti A, Tosi GM.
europepmc   +3 more sources

LEISHMANIA DONOVANI IN THE PERIPHERAL BLOOD [PDF]

Journal of Experimental Medicine, 1923
1. The effect of human red cells and serum on the growth of Leishmania donovani has been studied and a blood culture method devised, based on these findings. 2. The distribution of blood platelets and of the different varieties of leucocytes in the strata of centrifugalized diluted blood has been investigated, and also the distribution ...
C W, Young, H M, Van Sant
openaire   +2 more sources

Molecular mechanisms of drug resistance in natural Leishmania populations vary with genetic background [PDF]

, 2012
The evolution of drug-resistance in pathogens is a major global health threat. Elucidating the molecular basis of pathogen drug-resistance has been the focus of many studies but rarely is it known whether a drug-resistance mechanism identified is ...
Sylke Müller, Hideo Imamura (62469), Dujardin, J., Khanal, Basudha, Brunker, K., Brunker, Kirstyn, Kirstyn Brunker (181178), Graham H. Coombs (164011), Suman Rijal (181185), Imamura, Hideo, Jean-Claude Dujardin, M\ufcller, Sylke, Dujardin, Jean-Claude, Dujardin, J. C., Coombs, G. H., Muller, S., Jean-Claude Dujardin (56958), Decuypere, S., Coombs, G.H., Vanaerschot, M., Decuypere, Saskia, Coombs, Graham H, Rijal, S., Manu Vanaerschot, Sylke Müller (37476), Basudha Khanal, Khanal, B., Hideo Imamura, Kirstyn Brunker, Müller, Sylke, Coombs, Graham H., Vanaerschot, Manu, Imamura, H., Rijal, Suman, Saskia Decuypere, Basudha Khanal (181181), Saskia Decuypere (181176), Manu Vanaerschot (109210), Suman Rijal, Graham H Coombs, S Decuypere   +40 more
core   +5 more sources

Dendritic cell regulation of immunity to Leishmania donovani [PDF]

, 2010
Dendritic cells lie at the interface of innate and adaptive immunity, critically contributing to the generation of an antigen-specific immune response.
Owens, Benjamin M.J.
core   +6 more sources