Metformin Adjunct With Antineoplastic Agents for the Treatment of Lung Cancer: A Meta-Analysis of Randomized Controlled Trials and Observational Cohort Studies. [PDF]
Front Pharmacol, 2021 Objective: Resistance to anticancer agents ensures a poor prognosis in patients with lung cancer. Metformin could enhance the anticancer effects of standard antineoplastic agents [traditional chemotherapy drugs, epidermal growth factor receptor tyrosine ...
Luo X, Chen X, Wang L, Yang B, Cai S.
europepmc +4 more sources
Antineoplastic Agents Targeting Sphingolipid Pathways. [PDF]
Front Oncol, 2020 Emerging studies in the enigmatic area of bioactive lipids have made many exciting new discoveries in recent years. Once thought to play a strictly structural role in cellular function, it has since been determined that sphingolipids and their ...
Kroll A, Cho HE, Kang MH.
europepmc +4 more sources
Gold(III)–pyrrolidinedithiocarbamato Derivatives as Antineoplastic Agents** [PDF]
ChemistryOpen, 2015 Transition metals offer many possibilities in developing potent chemotherapeutic agents. They are endowed with a variety of oxidation states, allowing for the selection of their coordination numbers and geometries via the choice of proper ligands ...
C. Nardon +7 more
semanticscholar +4 more sources
External contamination of commercial containers by antineoplastic agents: a literature review. [PDF]
Eur J Hosp Pharm, 2020 The aim of this study was to review the literature regarding the external contamination of commercial vials by antineoplastic drugs. A PubMed and CINAHL searches from 1 January 1990 to 1 May 2018 was performed with the terms: « antineoplastic agents », «
Hilliquin D, Tanguay C, Bussières JF.
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Mucocutaneous Reactions to Antineoplastic Agents [PDF]
CA: A Cancer Journal for Clinicians, 1980 Mucocutaneous reaction patterns in patients receiving cancer therapy are not only variable, but in many instances identical patterns are produced by different pathologic mechanisms. For example, patients with leukemia or lymphoma may present with nodular skin lesions that may represent malignant infiltration, septic emboli, vasculitis, or a drug ...
R. M. Adrian +2 more
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Renal toxicity of antineoplastic agents
Toxicology Letters, 1990 Most of the drugs currently used in the treatment of cancer are highly cytotoxic and possess relatively low therapeutic selectivity. Given the major role of the kidney in the excretion of these drugs or their metabolites, it is perhaps surprising that clinically significant nephrotoxicity occurs with a limited number of drugs.
Richard F. Borch, Thomas J. Montine
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Role of glioblastoma stem cells in cancer therapeutic resistance: a perspective on antineoplastic agents from natural sources and chemical derivatives. [PDF]
Stem Cell Res Ther, 2021 Alves ALV +7 more
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Antineoplastic Agents Action and Toxicities [PDF]
AAOHN Journal, 1986 Bonnie Rogers
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International Journal of Oncology, 2014 Targeting the oxygen stress response pathway is considered a promising strategy to exert antineoplastic activity in a broad spectrum of tumor types.
H. Möhler, Rolf W. Pfirman, K. Frei
semanticscholar +3 more sources
Repression of the stress granule protein G3BP2 inhibits immune checkpoint molecule PD‐L1
Molecular Oncology, EarlyView., 2022 Mounting evidence suggests that cancer stemness and immunosuppression are related, but the underlying mechanisms are not clear. We previously reported that the stress granule‐associated protein G3BP2 is involved in regulating tumor‐initiating (stem) cells.
Yanhong Zhang +3 more
wiley +1 more source