Metformin Adjunct With Antineoplastic Agents for the Treatment of Lung Cancer: A Meta-Analysis of Randomized Controlled Trials and Observational Cohort Studies [PDF]
Objective: Resistance to anticancer agents ensures a poor prognosis in patients with lung cancer. Metformin could enhance the anticancer effects of standard antineoplastic agents [traditional chemotherapy drugs, epidermal growth factor receptor tyrosine ...
Xiaofeng Luo+8 more
doaj +3 more sources
Antineoplastic Agents Targeting Sphingolipid Pathways [PDF]
Emerging studies in the enigmatic area of bioactive lipids have made many exciting new discoveries in recent years. Once thought to play a strictly structural role in cellular function, it has since been determined that sphingolipids and their ...
Alexander Kroll+4 more
doaj +3 more sources
Emetic risk classification and evaluation of the emetogenicity of antineoplastic agents-updated MASCC/ESMO consensus recommendation. [PDF]
Purpose Our goal was to identify new anticancer agents approved by the US Food and Drug Administration (FDA) and the European Medical Agency (EMA) since the 2016 MASCC/ESMO antiemetic update and classify their emetic potential.
Jordan K+7 more
europepmc +2 more sources
Analysis of 12 cases of antineoplastic agents-induced interstitial lung disease [PDF]
Objective: To summarize the situation of antineoplastic agents-induced interstitial lung diseases (ILD), provide reference for strengthening clinical management of druginduced interstitial lung diseases (DILD).Methods: We retrospectively investigated the
Xiao Li+4 more
doaj +2 more sources
Influence of occupational exposure to antineoplastic agents on adverse pregnancy outcomes among nurses: A meta‐analysis [PDF]
Aim This study aimed to explore the relationship between nurses' occupational exposure to antineoplastic agents and adverse pregnancy outcomes. Design Meta‐analysis.
Shuhan Liu+7 more
doaj +2 more sources
Adaptation of Bacteria to Antineoplastic Agents Involves Persister Cells and Increases Resistance to Antibiotics [PDF]
The increasing number of life-threatening infections observed in cancer patients has been ascribed to chemotherapy-induced neutropenia and to invasive medical procedures such as surgery and the application of catheters.
Carla C. C. R. de Carvalho
doaj +2 more sources
Role of glioblastoma stem cells in cancer therapeutic resistance: a perspective on antineoplastic agents from natural sources and chemical derivatives. [PDF]
Glioblastoma (GBM) is the highest-grade form of glioma, as well as one of the most aggressive types of cancer, exhibiting rapid cellular growth and highly invasive behavior.
Alves ALV+7 more
europepmc +2 more sources
Public procurement of antineoplastic agents used for treating breast cancer in Brazil between 2013 and 2019 [PDF]
Background Breast cancer is the most common cancer among women in Brazil and the country’s public health care system is the main care provider. Timely treatment can increase the chance of cure, prevent metastasis and improve quality of life.
Ranailla Lima Bandeira dos Santos+2 more
doaj +2 more sources
Characterization of Antineoplastic Agents Inducing Taste and Smell Disorders Using the FAERS Database [PDF]
Taste and smell disorders can worsen the nutritional status of patients receiving chemotherapy and potentially affect drug treatment. However, there is limited knowledge on antineoplastic agents that induce taste and smell disorders.
Risa Hamazaki, Yoshihiro Uesawa
doaj +2 more sources
Promotion of tumor angiogenesis and growth induced by low-dose antineoplastic agents via bone-marrow-derived cells in tumor tissues [PDF]
BackgroundMore research is needed to solidify the basis for reasonable metronomic chemotherapy regimens due to the inconsistent clinical outcomes from studies on metronomic chemotherapy with antineoplastic agents, along with signs of a nonlinear dose ...
Huining You+8 more
doaj +2 more sources