Results 91 to 100 of about 17,757 (259)

Antioxidant supplementation in cancer: Potential interactions with conventional chemotherapy and radiation therapy [PDF]

open access: yes, 2001
Several issues are addressed in this discussion of the advantages and disadvantages of supplemental anti-oxidants during cancer treatment with chemotherapy and/or radiation ...
Staff, Clinic
core   +1 more source

Multidisciplinary Strategies for Targeting Tumor Dormancy in Breast Cancer Therapeutics: Hallmarks, Mechanism, and Approaches

open access: yesiMetaMed, EarlyView.
Clinical phases and classification of breast tumor dormancy. Tumor dormancy is described as the period after treatment until residual tumor cells become detectable as relapsing disease in clinic. During the period of clinical tumor dormancy, tumor mass dormancy and cellular dormancy may coexist.
Shu Chen   +4 more
wiley   +1 more source

Ovarian Cancer: Epidemiology, Disease Mechanisms, New Diagnosis and Treatment Strategies, and Research Directions

open access: yesiNew Medicine, EarlyView.
ABSTRACT Ovarian cancer (OC) continues to be the deadliest gynecological malignancy and a significant cause of cancer‐related mortality among women worldwide. Standard treatment strategies typically entail platinum‐based chemotherapy in conjunction with cytoreductive surgery.
Zunera Khalid   +4 more
wiley   +1 more source

Cáncer de seno y hormonoterapia: Estado actual Breast cancer and hormone therapy: Current state of knowledge

open access: yesRevista Colombiana de Cirugía, 2007
El manejo del cáncer de seno es multidisciplinario e involucra la cirugía, la quimioterapia, la radioterapia y la hormonoterapia. La hormonoterapia es un tratamiento muy antiguo para el manejo efectivo del cáncer de seno hormono-sensible. Cerca de 75% de
José Joaquín Caicedo M   +12 more
doaj  

N6‐Methyladenosine (m6A) in Liver Disease: Pathogenic Mechanisms and Therapeutic Potential

open access: yesiNew Medicine, EarlyView.
ABSTRACT Accumulating evidence highlights the critical role of epigenetic modifications, particularly N6‐methyladenosine (m6A), in liver disease. As the most abundant RNA modification in eukaryotic cells, m6A is dynamically regulated by multicomponent m6A methyltransferases (e.g., METTL3 and METTL14), demethylases (FTO and ALKBH5), and m6A‐binding ...
Yingfen Chen   +6 more
wiley   +1 more source

pH and salivary sodium bicarbonate in cancer patients : correlation with seric concentration [PDF]

open access: yes, 2008
Objective: To determine the correlation between pH and bicarbonate of soda in blood and saliva in child and adolescent patients during the administration of 3g/m2 of methotrexate.
Chaparro, Neira   +4 more
core  

The Role of Endothelin‐1 in Autoimmune Diseases: Mechanistic Insights and Therapeutic Targets

open access: yesiNew Medicine, EarlyView.
The Role of Endothelin‐1 in Autoimmune Diseases. NF‐κB: nuclear factor kappa‐B; MAPK: mitogen‐activated protein kinase; PI3K: phosphoinositide 3‐kinase; ROS: reactive oxygen species; CTGF: connective tissue growth factor; TGF‐β: transforming growth factor‐β.
Xun Gong   +5 more
wiley   +1 more source

Cáncer mamario en el hombre: Presentación de un caso y revisión de la literatura Breast cancer in man: Case report and literatura review

open access: yesRevista Colombiana de Cirugía, 2004
El cáncer mamario en el hombre se presenta con muy baja frecuencia y aunque su historia natural y características histológicas son similares al cáncer de seno femenino, su epidemiología y ambiente hormonal son diferentes.
Myriam Bravo de Insuasty   +2 more
doaj  

Non-steroidal anti-inflammatory drugs in cancer prevention and therapy [PDF]

open access: yes, 2007
Long-term use of non-steroidal anti-inflammatory drugs (NSAIDs) can be regarded as an effective approach for cancer chemoprevention, as demonstrated by a bulk of clinical and experimental evidence.
Del Monte, G   +5 more
core   +1 more source

SUMOylation regulates tumorigenesis and progression: Molecular mechanisms and therapeutic applications

open access: yesInterdisciplinary Medicine, EarlyView.
SUMOylation, a dynamic post‐translational modification, acts as a master regulator at the heart of tumor malignancy. Our work delineates how the SUMOylation cycle—mediated by E1/E2/E3 enzymes and reversed by SENPs—orchestrates multiple hallmarks of cancer. The central pathway converges on three critical pathological axes: 1.
Yimao Wu   +6 more
wiley   +1 more source

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