Results 81 to 90 of about 1,663,582 (244)
Engineering Bacteria for Medicine: Delivery, Diagnosis, and Therapy
iMetaMed, EarlyView.ABSTRACT With rapid advances in synthetic biology and genetic engineering, genetically engineered bacteria (GEB) have emerged as a promising platform for biological therapy, addressing key limitations of conventional drug delivery systems and demonstrating significant clinical potential.
Shiyu Xia +11 more
wiley +1 more source
Emetic risk classification and evaluation of the emetogenicity of antineoplastic agents—updated MASCC/ESMO consensus recommendation [PDF]
PURPOSE : Our goal was to identify new anticancer agents approved by the US Food and Drug Administration (FDA) and the European Medical Agency (EMA) since the 2016 MASCC/ESMO antiemetic update and classify their emetic potential. METHODS : The MASCC/ESMO
Jordan, Karin +7 more
core +3 more sources
Frontiers in PharmacologyObjectiveThe aim of this study is to characterize reporting patterns and non-treatment drug safety signals for diabetes insipidus (DI) in the FDA Adverse Event Reporting System (FAERS), evaluate signal stability using crude, adjusted, and shrinkage-based
Yiqi Li +6 more
doaj +1 more source
iMeta, EarlyView.The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li +29 more
wiley +1 more source
iNew Medicine, EarlyView.ABSTRACT Ovarian cancer (OC) continues to be the deadliest gynecological malignancy and a significant cause of cancer‐related mortality among women worldwide. Standard treatment strategies typically entail platinum‐based chemotherapy in conjunction with cytoreductive surgery.
Zunera Khalid +4 more
wiley +1 more source
Antineoplastic agents; occupational hazards in hospitals
"Antineoplastic agents are widely used in cancer therapy because they can inhibit growth by disrupting cell division and killing actively growing cells. These agents can also cause health effects among health care workers who work with them. A summary of
core
PurposeSurface wipe sampling for various hazardous agents has been employed in many occupational settings over the years for various reasons such as evaluation of potential dermal exposure and health risk, source determination, quality or cleanliness ...
core
ATP Citrate Lyase in Metabolic Disease: Mechanistic Insights and Clinical Potential
iNew Medicine, EarlyView.ATP citrate lyase (ACLY) is a central metabolic hub that diverts mitochondrial citrate to fuel de novo lipogenesis, cholesterol biosynthesis, and protein acetylation. Given its robust correlation with pathological changes in multiple human diseases, ACLY inhibitors featuring distinct pharmacological strengths have been developed for therapeutic ...
Wenbiao Wang +5 more
wiley +1 more source
PREVENTING AND MANAGEMENT OF EXTRAVASATION OF ANTINEOPLASTIC AGENTS: SCOPING REVIEW
, 2020 Objective: to identify and synthesize the scientific evidences about the event of extravasation in the administration of antineoplastic chemotherapy, with emphasis on prevention and conduct.
Deborah Franscielle da Fonseca +4 more
core +1 more source
Interdisciplinary Medicine, EarlyView.This comprehensive review highlights the transformative role of 3D printing and bioprinting technologies in the regeneration of female reproductive organs and the treatment of gynecological diseases. Unlike previous overviews that focus narrowly on isolated applications, this work provides an integrative analysis of recent clinical and preclinical ...
Chan Hum Park, In‐Sun Hong
wiley +1 more source