Results 11 to 20 of about 21,581 (165)

Gastrointestinal perforation associated with novel antineoplastic agents: A real-world study based on the FDA Adverse Event Reporting System

Journal of Pharmacy & Pharmaceutical Sciences, 2023
Purpose: Gastrointestinal perforation (GIP) is a fatal adverse event (AE). The AE of GIP induced by novel antineoplastic agents has attracted attention recently.
Zicheng Yu, Haibin Zhu, Hongjun Chen, Lifei Zhu, Xiaolan Liao   +4 more
semanticscholar   +1 more source

Combination of Antimalarial and CNS Drugs with Antineoplastic Agents in MCF-7 Breast and HT-29 Colon Cancer Cells: Biosafety Evaluation and Mechanism of Action

Biomolecules, 2022
Drug combination and drug repurposing are two strategies that allow to find novel oncological therapies, in a faster and more economical process. In our previous studies, we developed a novel model of drug combination using antineoplastic and different ...
Diana Duarte, Mariana Nunes, S. Ricardo, N. Vale   +3 more
semanticscholar   +1 more source

Hybrid Molecules Containing Naphthoquinone and Quinolinedione Scaffolds as Antineoplastic Agents

Molecules, 2022
In recent decades, molecular hybridization has proven to be an efficient tool for obtaining new synthetic molecules to treat different diseases. Based on the core idea of covalently combining at least two pharmacophore fragments present in different ...
I. Mancini, Jacopo Vigna, D. Sighel, A. Defant   +3 more
semanticscholar   +1 more source

Role of glioblastoma stem cells in cancer therapeutic resistance: a perspective on antineoplastic agents from natural sources and chemical derivatives

Stem cell research & therapeutics, 2021
Glioblastoma (GBM) is the highest-grade form of glioma, as well as one of the most aggressive types of cancer, exhibiting rapid cellular growth and highly invasive behavior.
A. L. V. Alves, I. Gomes, A. Carloni, M. N. Rosa, L. D. da Silva, A. Evangelista, R. Reis, V. Silva   +7 more
semanticscholar   +1 more source

Metformin Adjunct With Antineoplastic Agents for the Treatment of Lung Cancer: A Meta-Analysis of Randomized Controlled Trials and Observational Cohort Studies

Frontiers in Pharmacology, 2021
Objective: Resistance to anticancer agents ensures a poor prognosis in patients with lung cancer. Metformin could enhance the anticancer effects of standard antineoplastic agents [traditional chemotherapy drugs, epidermal growth factor receptor tyrosine ...
Xiaofeng Luo, Xi Chen, Lin Wang, Bowen Yang, S. Cai   +4 more
semanticscholar   +1 more source

Nested Case‐Control Study Utilizing MID‐NET® on Thrombocytopenia Associated With Pegfilgrastim in Patients Treated With Antineoplastic Agents

Clinical pharmacology and therapy, 2021
Although several spontaneous case reports on the occurrence of thrombocytopenia in patients treated with human granulocyte colony‐stimulating factor (G‐CSF) preparations have been accumulated, its actual causality is still unclear.
K. Kajiyama, Chieko Ishiguro, T. Ando, Y. Kubota, Natsumi Kinoshita, Y. Oniyama, T. Iguchi, Y. Uyama   +7 more
semanticscholar   +1 more source

Influence of the treatment with the antineoplastic agents 5-fluorouracil and cisplatin on the severity of experimental periodontitis in rats

Supportive Care in Cancer, 2021
The determination on how antineoplastic agents interfere on the progression of periodontitis is critical for improvement and even development of novel therapeutic approaches for periodontal management.
V. Novaes, E. Ervolino, Giovani Lopes Fernandes, Clara Possarle Cunha, L. Theodoro, V. Garcia, J. D. de Almeida   +6 more
semanticscholar   +1 more source

Drug Release from Ordered Mesoporous Silicas [PDF]

, 2015
The state-of-the-art in the investigation of drugs release from Silica-based ordered Mesoporous Materials (SMMs) is reviewed. First, the SMM systems used like host matrixes are described.
Doadrio Villarejo, Antonio Luis, Salinas Sánchez, Antonio J., Sánchez-Montero, José M., Vallet Regí, María   +3 more
core   +2 more sources

Chemical Profiles of Essential Oils and Non-Polar Extractables from Sumac (Rhus spp.) [PDF]

, 2011
Sumac is the common name for a genus (Rhus) with >250 individual species of flowering plants in the family Anacardiaceae. These plants are globally distributed in temperate and tropical regions and can grow on marginal lands, making them strong ...
Sierra Rayne
core   +2 more sources

Vinorelbine-induced regression of a choroidal metastasis from primary breast carcinoma

International Journal of Retina and Vitreous, 2018
Background Various therapeutic options exist to treat choroidal metastatic lesions. However, they are all associated with potential long-term adverse effects.
Malvika Arya, Jay S. Duker
doaj   +1 more source