Results 21 to 30 of about 1,515,750 (130)

Discovery of a Novel γ‐Glutamylcyclotransferase Inhibitor Plumbagin by Luminescence‐Based High‐Throughput Screening

Cancer Science, Volume 117, Issue 6, Page 1713-1723, June 2026.
A cell‐based high‐throughput screening system utilizing the luminescent probe LISA‐103 was developed to monitor γ‐glutamylcyclotransferase (GGCT) activity in cancer cells. Through this assay, plumbagin was identified as a novel GGCT inhibitor that induces cell cycle arrest and suppresses cancer cell growth. ABSTRACT γ‐Glutamylcyclotransferase (GGCT) is
Keiko Taniguchi, Yukie Nohara, Mano Horinaka, Kozue Nose, Masaya Mori, Hiromi Ii, Hiroko Kawakami, Kazuto Yano, Susumu Nakata, Taku Yoshiya, Toshiyuki Sakai   +10 more
wiley   +1 more source

Safe prescription of systemic antineoplastic treatment in oncology: integrative literature review

, 2022
The objective of this study was to identify the available evidence on the parameters that should be considered to improve the quality and safety of the prescription of systemic antineoplastic treatment.
Paula Elaine Diniz dos Reis, Elaine Barros Ferreira, Renata Cristina de Campos Pereira Silveira, Fabiola Vasconcelos Alves, Flavia Oliveira de Almeida Marques da Cruz   +4 more
core   +1 more source

Phytochemistry and Bioactivities of Thymol and Carvacrol: Molecular Pathways, Metabolism, and Therapeutic Insights

Food Science &Nutrition, Volume 14, Issue 4, April 2026.
Thymus serpyllum (wild thyme) contains bioactive compounds such as carvacrol, thymol, β‐caryophyllene, γ‐terpinene, and α‐thujene, along with essential vitamins and minerals. These constituents exhibit antioxidant, antimicrobial, anti‐inflammatory, and antidiabetic activities.
Ahmad Mujtaba Noman, Muhammad Tauseef Sultan, Farhang Hameed Awlqadr, Hassan Raza, Shehnshah Zafar, Aimen Mazhar, Duaa Tariq, Muhammed Noori Saeed, Khaled Arab   +8 more
wiley   +1 more source

Biochemical aspects of the combined use of taxanes, irradiation and other antineoplastic agents for the treatment of anaplastic thyroid carcinoma

, 2018
The review summarizes the results of the cycle of own research and literature data on biochemical mechanisms of combined action of taxanes with γ-irradiation and other antineoplastic agents on one of the most aggressive types of human cancer – anaplastic
O. I. Kovzun, V. M. Pushkarev, V. V. Pushkarev, B. B. Guda, M. D. Tronko   +4 more
core   +1 more source

Emetic risk classification and evaluation of the emetogenicity of antineoplastic agents—updated MASCC/ESMO consensus recommendation [PDF]

, 2023
PurposeOur goal was to identify new anticancer agents approved by the US Food and Drug Administration (FDA) and the European Medical Agency (EMA) since the 2016 MASCC/ESMO antiemetic update and classify their emetic potential.MethodsThe MASCC/ESMO Expert
Jordan, Karin, Chan, Alexandre, Ruhlmann, Christina H, Hesketh, Paul J, Sayegh, Paula, Gralla, Richard J., Jahn, Franziska, Hesketh, Paul J., Rapoport, Bernardo, Ruhlmann, Christina H., Gralla, Richard J   +10 more
core   +1 more source

Green Synthesis of Metal Oxide Nanoparticles Using Plant Extracts: Applications in Catalysis and Biomedicine

Nano Select, Volume 7, Issue 3, March 2026.
ABSTRACT The green synthesis of metal oxide nanoparticles (MONPs) using plant‐based resources has gained significant traction as an environmentally benign, cost‐effective, and scalable alternative to traditional chemical and physical methods. This review comprehensively explores the plant‐mediated synthesis routes for a variety of MONPs, including CuO,
Faith Mwangi, Jannatun Zia, Ufana Riaz
wiley   +1 more source

Monoterpenes: Functional Additives for Reducing Antibiotics in Aquaculture

Reviews in Aquaculture, Volume 18, Issue 1, January 2026.
ABSTRACT Aquaculture is a rapidly growing industry that supplies fish for global consumption. However, the intensive production practices have resulted in disease outbreaks, largely driven by the misuse of antibiotics. Natural alternatives, such as monoterpenes, which are biocompounds derived from essential oils obtained from plants like thyme and ...
Danilo Vitor Vilhena Batista, Barbara Silveira Souza, Caio Francisco Santana Farias, Ana Paula de Souza, Alexandre Vaz da Silva, Emilly Monteiro Lopes, Elenice Martins Brasil, Maurício Laterça Martins, José Luiz Pedreira Mouriño, Marco Shizuo Owatari   +9 more
wiley   +1 more source

Plant‐Mediated Fabrication of Silver Nanoparticles Using Elaeagnus angustifolia Flowers: In Vitro Evaluation of Antibacterial, Antifungal, Antioxidant, and Toxic Effects and Biomolecular Interactions With ct‐DNA and HSA

Bioinorganic Chemistry and Applications, Volume 2026, Issue 1, 2026.
This study aimed to biosynthesize silver nanoparticles using Elaeagnus angustifolia flower buds—an Iranian medicinal plant extract rich in bioactive phytochemicals and evaluate their antimicrobial potential through complementary broth microdilution (MIC/MBC) and agar well diffusion assays, alongside an assessment of their anticancer and biomolecular ...
Nahid Shahabadi, Kani Shalmashi, Sedigheh Shokraei, Leila Soltani, Demetrio Milea   +4 more
wiley   +1 more source

Potential of Dietary Microalgae as Feed Additive in Japanese Quail

Veterinary Medicine International, Volume 2026, Issue 1, 2026.
Due to substantial increase of human population, demand for sustainable protein sources of livestock, poultry, and fish also increases. To meet the escalating demand for protein‐rich food, there is also need of finding suitable feed ingredients to improve the growth and health of poultry especially quails.
Tahreem Fatima, Mamoona Tahir, Aqsa Hameed, Faiza Shahzadi, Shabana Naz, Amna Sajjad, Maleeha Manzoor, Lipi Buch   +7 more
wiley   +1 more source

Preventing Medication Errors with Antineoplastic Agents, Part 2

, 2000
Goal The goal of this program is to present practical ways to prevent medication errors with antineoplastic agents, identify common types of medication errors, and describe a system for reducing and responding appropriately to antineoplastic medication ...
Linda S. Tyler, M. Christina Beckwith
core   +1 more source