Results 11 to 20 of about 7,199 (99)

Ethnopharmacological Potential of Phytochemicals and Phytogenic Products against Human RNA Viral Diseases as Preventive Therapeutics

BioMed Research International, Volume 2023, Issue 1, 2023., 2023
RNA viruses have been the most destructive due to their transmissibility and lack of control measures. Developments of vaccines for RNA viruses are very tough or almost impossible as viruses are highly mutable. For the last few decades, most of the epidemic and pandemic viral diseases have wreaked huge devastation with innumerable fatalities. To combat
Anamika Paul, Nilanjan Chakraborty, Anik Sarkar, Krishnendu Acharya, Anuj Ranjan, Abhishek Chauhan, Shilpi Srivastava, Akhilesh Kumar Singh, Ashutosh Kumar Rai, Iqra Mubeen, Ram Prasad, Mohd Saeed   +11 more
wiley   +1 more source

Myelosuppression Alleviation and Hematopoietic Regeneration by Tetrahedral‐Framework Nucleic‐Acid Nanostructures Functionalized with Osteogenic Growth Peptide

Advanced Science, Volume 9, Issue 27, September 23, 2022., 2022
Osteogenic growth peptide regulates the bone marrow microenvironment to promote blood cell formation. Tetrahedral nucleic‐acid nanostructures are excellent drug delivery vehicles with additional positive side effects in regenerative medicine. Abstract As major complications of chemoradiotherapy, myelosuppression and hematopoietic‐system damage severely
Tianxu Zhang, Mi Zhou, Dexuan Xiao, Zhiqiang Liu, Yueying Jiang, Maogeng Feng, Yunfeng Lin, Xiaoxiao Cai   +7 more
wiley   +1 more source

Thymol and carvacrol supplementation in poultry health and performance

Veterinary Medicine and Science, Volume 8, Issue 1, Page 267-288, January 2022., 2022
Abstract Background Thymol and carvacrol as natural essential oils and phenol compounds are components derived from some medicinal plants, such as thyme and oregano species. Objectives The increasing demands in organic and healthy meat and egg consumption in human society have made it necessary to consider alternative natural compounds for the ...
Majid Gholami‐Ahangaran, Asiye Ahmadi‐Dastgerdi, Shahrzad Azizi, Asal Basiratpour, Maryam Zokaei, Masoud Derakhshan   +5 more
wiley   +1 more source

Advanced Practical Strategies to Enhance Table Egg Production

Scientifica, Volume 2022, Issue 1, 2022., 2022
The global demand for table eggs has increased exponentially due to the growing human population. To meet this demand, major advances in hen genetics, nutrition, and husbandry procedures are required. Developing cost‐effective and practically applicable strategies to improve egg production and quality is necessary for the development of egg industry ...
Karim El-Sabrout, Sarah Aggag, Birendra Mishra, Luis T. Ortiz   +3 more
wiley   +1 more source

Activation of SAPK/JNK by camptothecin sensitizes androgen-independent prostate cancer cells to Fas-induced apoptosis

, 2000
We have previously shown that the androgen-independent prostate cancer cells DU145, despite expressing Fas and FasL, were resistant to anti-Fas-induced apoptosis, and that this resistance could be overcome by pretreating the cells with sublethal doses of

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Resistance to paclitaxel is proportional to cellular total antioxidant capacity

, 2005
Paclitaxel, one of the most commonly prescribed chemotherapeutic agents, is active against a wide spectrum of human cancer. The mechanism of its cytotoxicity, however, remains controversial. Our results indicate that paclitaxel treatment increases levels

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Discovery of a Novel γ‐Glutamylcyclotransferase Inhibitor Plumbagin by Luminescence‐Based High‐Throughput Screening

Cancer Science, Volume 117, Issue 6, Page 1713-1723, June 2026.
A cell‐based high‐throughput screening system utilizing the luminescent probe LISA‐103 was developed to monitor γ‐glutamylcyclotransferase (GGCT) activity in cancer cells. Through this assay, plumbagin was identified as a novel GGCT inhibitor that induces cell cycle arrest and suppresses cancer cell growth. ABSTRACT γ‐Glutamylcyclotransferase (GGCT) is
Keiko Taniguchi, Yukie Nohara, Mano Horinaka, Kozue Nose, Masaya Mori, Hiromi Ii, Hiroko Kawakami, Kazuto Yano, Susumu Nakata, Taku Yoshiya, Toshiyuki Sakai   +10 more
wiley   +1 more source

Differentiated human colorectal cancer cells protect tumor-initiating cells from irinotecan

, 2011
BACKGROUND & AIMS: Stem cells of normal tissues have resistance mechanisms that allow them to survive genotoxic insults. The stem cell-like cells of tumors are defined by their tumor-initiating capacity and may have retained these resistance mechanisms ...
Vries, R.G.J., Andre Verheem, Steller, E.J.A., Vries, R.G., Hans Clevers, Van Houdt, W.J., Maarten W. Nijkamp, Connie R. Jimenez, Hoogwater, F.J.H., Hoogwater, F.J., Winan J. Van Houdt, Robert G. Vries, Clevers, H., Inne H.M. Borel Rinkes, Govaert, K.M., Jimenez, C.R., Benjamin L. Emmink, Nijkamp, M.W., Kranenburg, O., Emmink, B.L., Rinkes, I.H.M.B., Verheem, A., Frederik J.H. Hoogwater, Houdt, W.J., Steller, E.J., Ernst J.A. Steller, Onno Kranenburg, Rinkes, I.H., Klaas M. Govaert   +28 more
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Phytochemistry and Bioactivities of Thymol and Carvacrol: Molecular Pathways, Metabolism, and Therapeutic Insights

Food Science &Nutrition, Volume 14, Issue 4, April 2026.
Thymus serpyllum (wild thyme) contains bioactive compounds such as carvacrol, thymol, β‐caryophyllene, γ‐terpinene, and α‐thujene, along with essential vitamins and minerals. These constituents exhibit antioxidant, antimicrobial, anti‐inflammatory, and antidiabetic activities.
Ahmad Mujtaba Noman, Muhammad Tauseef Sultan, Farhang Hameed Awlqadr, Hassan Raza, Shehnshah Zafar, Aimen Mazhar, Duaa Tariq, Muhammed Noori Saeed, Khaled Arab   +8 more
wiley   +1 more source

High Bcr-Abl expression prevents the translocation of Bax and Bad to the mitochondrion

, 2002
Bcr-Abl is a constitutively active tyrosine kinase involved in the development and progression of chronic myeloid leukaemia (CML). It has been demonstrated that Bcr-Abl-positive cells can be uniquely resistant to apoptosis induced by different types of ...

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