Toxicological study and efficacy of blank and paclitaxel-loaded lipid nanocapsules after i.v. administration in mice [PDF]
PURPOSE: Lipid nanocapsules (LNCs) are solvent-free drug nanocarriers permitting entrapment of paclitaxel and increasing its antitumoural effect in animal models after i.v. injection.
F. Gagnadoux+6 more
core +3 more sources
Advanced glycation inhibition and protection against endothelial dysfunction induced by coumarins and procyanidins from Mammea neurophylla. [PDF]
Advanced glycation end-products (AGEs) are associated with many pathogenic disorders such as pathogenesis of diabetes or endothelial dysfunction leading to cardiovascular events. Therefore, the identification of new anti-AGE molecules or extracts aims at
B. Charreau+13 more
core +3 more sources
Search Strategies for Retrieving Complementary and Alternative Medicine Clinical Trials in Oncology
Purpose: Several Medline search strategies exist to retrieve complementary and alternative medicine (CAM) literature related to oncology. The objective of this study was to compare different search methods to ascertain the most optimal strategy. Methods:
A. Bardia+3 more
semanticscholar +1 more source
Cytotoxic xanthones isolated from Calophyllum depressinervosum and Calophyllum buxifolium with antioxidant and cytotoxic activities [PDF]
The stem bark of Calophyllum depressinervosum and Calophyllum buxifolium were extracted and examined for their antioxidant activities, together with cytotoxicity towards human cancer cells. The methanol extract of C.
Ee, Gwendoline Cheng Lian+4 more
core +1 more source
Actividad citotóxica y antiproliferativa de un extracto rico en fucoidan de Lessonia trabeculata sobre células de adenocarcinoma mamario murino 4T1 [PDF]
Neoplastic tumors are characterized by invasiveness and metastasis. Neoplasticcells are genetically heterogeneous and can develop resistance to chemotherapeutic agents.
Alzamora-Gonzales, Libertad+5 more
core +2 more sources
Biomonitoring of pharmacists and nurses at occupational risk from handling antineoplastic agents
The objective of this study was to evaluate the frequency of genetic lesions in pharmacists and nurses who prepare and/or handle antineoplastic agents and to evaluate whether there are traces of contaminants in the urine of these professionals.
Andreza Negreli Santos+4 more
semanticscholar +1 more source
Background Permeability of antineoplastic agents through medical gloves is an important factor that must be considered for the appropriate selection of gloves.
Toyohito Oriyama+6 more
semanticscholar +1 more source
Antitumor Cannabinoid Chemotypes: Structural Insights [PDF]
Cannabis has long been known to limit or prevent nausea and vomiting, lack of appetite, and pain. For this reason, cannabinoids have been successfully used in the treatment of some of the unwanted side effects caused by cancer chemotherapy. Besides their
Nadine Jagerovic, Paula Morales
core +1 more source
An updated pharmacological insight into calotropin as a potential therapeutic agent in cancer [PDF]
Calotropin is a pharmacologically active compound isolated from milkweed plants like Calotropis procera, Calotropis gigantea, and Asclepias currasavica that belong to the Asclepiadaceae family.
Alibek Ydyrys+7 more
core +3 more sources
Data on drug–drug interactions (DDI) of antineoplastic drugs with anticoagulants is scarce. We aim to evaluate factors associated with DDI of antineoplastic and supportive care drugs with anticoagulants resulting in modification of pharmacokinetics of ...
É. P. D. Peixoto de Miranda+6 more
semanticscholar +1 more source