Toxicological study and efficacy of blank and paclitaxel-loaded lipid nanocapsules after i.v. administration in mice [PDF]
, 2010 PURPOSE: Lipid nanocapsules (LNCs) are solvent-free drug nanocarriers permitting entrapment of paclitaxel and increasing its antitumoural effect in animal models after i.v. injection.
F. Gagnadoux +6 more
core +4 more sources
BioMed Research International, Volume 2022, Issue 1, 2022., 2022 Challenges encountered in relapse of illness caused by resistance of microorganisms to antimicrobial agents (drugs) are due to factors of severe stress initiated by random use of antibiotics and insufficient beneficial approaches. These challenges have resulted to multiple drug resistance (MDR) and, subsequently, biofilm formation.
Ayodele T. Odularu +5 more
wiley +1 more source
Advanced glycation inhibition and protection against endothelial dysfunction induced by coumarins and procyanidins from Mammea neurophylla. [PDF]
, 2014 Advanced glycation end-products (AGEs) are associated with many pathogenic disorders such as pathogenesis of diabetes or endothelial dysfunction leading to cardiovascular events. Therefore, the identification of new anti-AGE molecules or extracts aims at
B. Charreau +13 more
core +4 more sources
Advanced Science, Volume 8, Issue 11, June 9, 2021., 2021 A microfluidic platform is presented that builds on the advancement of a spheroid‐on‐a‐chip technology that accommodates 360 spheroids of five different dimensions on a microtiter plate format supporting a range of human tissue models. Thus, this platform closes an essential technological gap, enabling rapid and easy production of spheroids of defined ...
Christoph Eilenberger +11 more
wiley +1 more source
Actividad citotóxica y antiproliferativa de un extracto rico en fucoidan de Lessonia trabeculata sobre células de adenocarcinoma mamario murino 4T1 [PDF]
, 2023 Neoplastic tumors are characterized by invasiveness and metastasis. Neoplasticcells are genetically heterogeneous and can develop resistance to chemotherapeutic agents.
Alzamora-Gonzales, Libertad +5 more
core +2 more sources
Cytotoxic xanthones isolated from Calophyllum depressinervosum and Calophyllum buxifolium with antioxidant and cytotoxic activities [PDF]
, 2019 The stem bark of Calophyllum depressinervosum and Calophyllum buxifolium were extracted and examined for their antioxidant activities, together with cytotoxicity towards human cancer cells. The methanol extract of C.
Ee, Gwendoline Cheng Lian +4 more
core +1 more source
Phytochemicals as antibiotic alternatives to promote growth and enhance host health [PDF]
, 2018 There are heightened concerns globally on emerging drug-resistant superbugs and the lack of new antibiotics for treating human and animal diseases. For the agricultural industry, there is an urgent need to develop strategies to replace antibiotics for ...
A Costabile +145 more
core +5 more sources
An updated pharmacological insight into calotropin as a potential therapeutic agent in cancer [PDF]
, 2023 Calotropin is a pharmacologically active compound isolated from milkweed plants like Calotropis procera, Calotropis gigantea, and Asclepias currasavica that belong to the Asclepiadaceae family.
Alibek Ydyrys +7 more
core +3 more sources
Antitumor Cannabinoid Chemotypes: Structural Insights [PDF]
, 2019 Cannabis has long been known to limit or prevent nausea and vomiting, lack of appetite, and pain. For this reason, cannabinoids have been successfully used in the treatment of some of the unwanted side effects caused by cancer chemotherapy. Besides their
Nadine Jagerovic, Paula Morales
core +1 more source
Functional/Activity Network (FAN) Analysis of Gene-Phenotype Connectivity Liaised by Grape Polyphenol Resveratrol [PDF]
, 2016 Resveratrol is a polyphenol that has witnessed an unprecedented yearly growth in PubMed citations since the late 1990s. Based on the diversity of cellular processes and diseases resveratrol reportedly affects and benefits, it is likely that the interest ...
Bennett, Dylan J +5 more
core +2 more sources