Results 101 to 110 of about 3,462,732 (382)

Adherence to oral antineoplastic agents by cancer patients: definition and literature review.

European Journal of Cancer Care, 2014
Since the 1990s, oral chemotherapy has been gaining ground as cancer treatment. This therapy seems to have few toxic effects and offers patients good quality of life.
Fanny Bassan, F. Peter, B. Houbre, M. Brennstuhl, M. Costantini, É. Speyer, C. Tarquinio   +6 more
semanticscholar   +1 more source

Berberine and Coptidis Rhizoma as novel antineoplastic agents: A review of traditional use and biomedical investigations [PDF]

, 2009
Ethnopharmacological relevance: Coptidis Rhizoma (Huanglian) and its major component, berberine, have drawn extensive attention toward their antineoplastic effects in the recent years.
Curtain, R, Feng, Y, Tang, J, Tsao, S, Wang, N, Wang, Y   +5 more
core   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

TREX1, a predator for treating MSI‐H tumors?

Molecular Oncology, EarlyView.
Immunotherapy benefits many patients; yet, some with MSI‐H tumors remain unresponsive despite their high immunogenicity. Xu et al. reveal that TREX1 enables immune evasion by degrading cytosolic DNA and suppressing cGAS–STING–IFN‐I signaling. TREX1 loss restores DNA sensing, increases CD8+ T and NK cell infiltration, and boosts antitumor immunity ...
Elena Benidovskaya, Joséphine Deneft, Marc Van den Eynde   +2 more
wiley   +1 more source

Comparison of Addition of Indications for Antineoplastic Agents Approved in the United States and Japan from 2001 to 2020

, 2023
Toshiyuki Shizuya, Seiko Miyazaki
openalex   +2 more sources

Effect of the ionic antineoplastic agent Cytoreg on blood chemistry in the Wistar rat model [PDF]

, 2020
Katiusca Villasana, William Lobo Quintero, Yepsys Montero, Cristian Pino, Oscar Uzc tegui, Geizon Torres, Mariangel Prada, Lewis Pozo, William E. Bauta, William Jiménez   +9 more
openalex   +1 more source

Identification of Pharmacological Modulators of HMGB1-Induced Inflammatory Response by Cell-Based Screening [PDF]

, 2013
High mobility group box 1 (HMGB1), a highly conserved, ubiquitous protein, is released into the circulation during sterile inflammation (e.g. arthritis, trauma) and circulatory shock.
A Lahat, AJ Ghio, AM Colangelo, B Cai, B Lu, C Lagathu, C Szabo, Csaba Szabo, D Ditsworth, D Gero, D Gero, Domokos Gerö, E Venereau, EA Park, GY Chen, H Schierbeck, H Selye, H Wang, H Yang, H Yang, H Yang, HE Harris, Huan Yang, J Evankovich, J Szelenyi, John P. Pribis, JR Klune, Katalin Módis, Kevin J. Tracey, KJ Tracey, L Ulloa, ME Bianchi, O Hori, Petra Szoleczky, PJ Barnes, R Bertini, Robert W. Sobol, Sangeeta Chevan, Timothy R. Billiar, U Andersson, Yousef Al-Abed   +40 more
core   +4 more sources

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Growth inhibition and anticancer activity of phenoxyartemisinin derivatives in various cancer cell lines [PDF]

Journal of Medicine and Life Science
Cancer remains a significant global health challenge, underscoring the need for novel antineoplastic agents with improved efficacy and reduced toxicity.
Sangtae Oh, Seokjoon Lee, Woon-seob Shin, Nam Hyun Kim   +3 more
doaj   +1 more source

Metformin as Antineoplastic Agent Against Glioblastoma

, 2023
Daewoo Hong, Ahmed Khan, Jorge Cervantes
openalex   +2 more sources