Results 111 to 120 of about 210,920 (352)

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

Molecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova, Dominika Maurencova, Barbora Salovska, Marek Kratky, Tomas Mracek, Zuzana Korandova, Alena Pecinova, Pavla Vasicova, David Rysanek, Ladislav Andera, Ivo Fabrik, Rudolf Kupcik, Pavel Kashmel, Pinky Sultana, Vojtech Tambor, Jiri Bartek, Josef Novak, Marie Vajrychova, Zdenek Hodny   +18 more
wiley   +1 more source

Evidence-Based Practice Considerations In Facilitating The Risk Surveillance Of Occupational Exposure To Antineoplastic Agents [PDF]

, 2005
According to Martin and Larson (2003), healthcare professionals involved with handling antineoplastic drugs may be exposed inadvertently to these agents, placing them at potential risk for acute and long-term adverse effects.
Rafique, Theresa A.
core   +1 more source

Vandetanib has antineoplastic activity in anaplastic thyroid cancer, in vitro and in vivo [PDF]

, 2018
The antitumor activity of vandetanib [a multiple signal transduction inhibitor including the RET tyrosine kinase, epidermal growth factor receptor (EGFR), vascular endothelial growth factor (VEGF) receptor (VEGFR), ERK and with antiangiogenic activity ...
Antonelli, Alessandro, Baldini, Enke, Bocci, Guido, Di Desidero, Teresa, Elia, Giusy, Fallahi, Poupak, Ferrari, Silvia Martina, Fioravanti, Anna, La Motta, Concettina, Materazzi, Gabriele, Miccoli, Paolo, Orlandi, Paola, Paparo, Sabrina Rosaria, Patrizio, Armando, Piaggi, Simona, Ragusa, Francesca, Ruffilli, Ilaria, Ulisse, Salvatore   +17 more
core   +2 more sources

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

Molecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma, Sophia M. Orbach, Kate V. Griffin, Kathryn Kang, Yining Zhang, Rebecca S. Pereles, Ian A. Schrack, Guillermo Escalona, Jacqueline S. Jeruss, Lonnie D. Shea   +9 more
wiley   +1 more source

Possible attenuation of the G2 DNA damage cell cycle checkpoint in HeLa cells by extremely low frequency (ELF) electromagnetic fields [PDF]

, 2002
BACKGROUND: The issue remains unresolved as to whether low frequency magnetic fields can affect cell behaviour, with the possibility that they may be in part responsible for the increased incidence of leukaemia in parts of the population exposed to ...
Harris, Paul A., Heaton, Brian, Lamb, Justin, Wheatley, Denys N.   +3 more
core   +3 more sources

Software Agents Interaction Algorithms in Virtual Learning Environment [PDF]

The World of Computer Science and Information Technology Journal (WSCIT). 2014, Volume 4, Issue 2. pp. 18.25, 2014
This paper highlights the multi-agent learning virtual environment and agents communication algorithms. The researcher proposed three algorithms required software agents interaction in virtual learning information system environment. The first proposed algorithm is agents interaction localization algorithm, the second one is the dynamic agents ...
arxiv  

NPC1 promotes the progression of hepatocellular carcinoma by mediating the accumulation of neutrophils into the tumor microenvironment

FEBS Open Bio, Volume 15, Issue 4, Page 661-673, April 2025.
Compared to normal tissues, NPC1 expression is significantly elevated in hepatocellular carcinoma tissues. Our findings indicate that NPC1 plays a key role in regulating neutrophil recruitment within the tumor, which is a critical factor in the progression of hepatocellular carcinoma and is closely linked to poor patient outcomes.
Songhai Yang, Jiangming Chen, Kun Xie, Fubao Liu   +3 more
wiley   +1 more source

OCCURRENCE OF HUMAN MOTOR SYSTEM LESIONS IN PATIENTS UNDERGOING CHEMOTHERAPY: A SYSTEMATIC REVIEW WITH META-ANALYSIS

Journal of Cancer Rehabilitation
Background Chemotherapy results in toxic effects, causing damage to various systems, such as the human motor system. Objective To investigate the prevalence of lesions in the human motor system presented by patients undergoing chemotherapy treatment.
Jurandir da Silva Filho, Emmanuele Celina Souza dos Santos, Lucas Yuri Azevedo da Silva, Rayane de Nazaré Monteiro Brandão, Saul Rassy Carneiro   +4 more
doaj   +1 more source

O-39 CLINICAL CHARACTERISTICS AND OUTCOME OF DRUG-INDUCED LIVER INJURY DUE TO ANTINEOPLASTIC AND BIOLOGICAL AGENTS

Annals of Hepatology, 2023
Introduction and Objectives: Idiosyncratic drug-induced liver injury (DILI) caused by antineoplastic and biological agents is an emerging clinical burden in oncologic patients.
Fernando Bessone, Nelia Hernandez, Raymundo Parana, Maria Isabel Schinoni, Manuel Mendizabal, Adriana Sanchez, Vinicius Nunes, Ezequiel Ridruejo, Daniela Schiodi, Eduardo Fassio, Hugo Tanno, Norberto Tamagnone, Martin Tagle, Pedro Montes, I Medina-Caliz, Mercedes Robles-Díaz, Aida Ortega-Alonso, Miren García-Cortes, Hao Niu, Ismael Alvarez-Alvarez, Rocío Romero-Flores, M Isabel Lucena, Raul J Andrade   +22 more
doaj  

Synergistic antibacterial activity of baicalin in combination with oxacillin sodium against methicillin‐resistant Staphylococcus aureus

FEBS Open Bio, Volume 15, Issue 4, Page 608-621, April 2025.
The bacterial cell membrane and cell wall are the primary targets of baicalin. Baicalin increases the permeability of bacterial membranes, allowing oxacillin sodium to easily penetrate the cells and effectively exert its antimicrobial activity. Methicillin‐resistant Staphylococcus aureus (MRSA) poses a challenge for clinical treatment and combining ...
Xin Meng, Mengna Kang, Zhiyun Yu, Changyou Li, Yang Chen, Taicheng Jin, Kai Wang, Haiyong Guo   +7 more
wiley   +1 more source