Results 121 to 130 of about 210,920 (352)
Recent advances in locoregional chemotherapy have opened the door to new approaches for the clinical management of peritoneal carcinomatosis (PC) by facilitating the delivery of anti-neoplastic agents directly to the tumor site, while mitigating adverse ...
Ceelen, Wim+4 more
core +1 more source
Newcastle disease virus as an antineoplastic agent [PDF]
William A. Cassel, R. Earl Garrett
openalex +1 more source
Osimertinib reduces angiogenesis and PDL1 expression in in ovo tumors, transforming them into ‘cold tumors’ with lower immune activity. Anatomopathological and transcriptomic analyses highlight its therapeutic impact on tumor biology. This study underscores osimertinib's potential to reshape the tumor microenvironment and provides insights into its ...
David Barthélémy+14 more
wiley +1 more source
Antineoplastic agents. XIX. N-Bis(2-haloethyl)glycine amides [PDF]
George R. Pettit+2 more
openalex +1 more source
Identification of inhibitors of the Salmonella FraB deglycase, a drug target
A high‐throughput screen was used to identify inhibitors of Salmonella FraB, a drug target. Characterization of top hits (identified after an additional counter screen) revealed that some triazolidines, thiadiazolidines, and triazolothiadiazoles are mixed‐type inhibitors of FraB.
Jamison D. Law+6 more
wiley +1 more source
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik+3 more
wiley +1 more source
Macroalgae Extracts From Antarctica Have Antimicrobial and Anticancer Potential
Background: Macroalgae are sources of bioactive compounds due to the large number of secondary metabolites they synthesize. The Antarctica region is characterized by extreme weather conditions and abundant aggregations of macroalgae.
Rosiane M. Martins+6 more
doaj +1 more source
European Union pharmacovigilance capabilities : potential for the new legislation [PDF]
European Directives and Regulations introduced between late 2010 and 2012 have substantially overhauled pharmacovigilance processes across the European Union (EU).
Aislaitner, George+6 more
core +1 more source
Acute cardiac toxicity of antineoplastic agents as the first manifestation of pheochromocytoma [PDF]
Diosdado N. Deasis+3 more
openalex +1 more source
Languages for Mobile Agents [PDF]
Mobile agents represent a new model for network computing. Many different languages have been used to implement mobile agents. The characteristics that make a language useful for writing mobile agents are: (1) their support of agent migration, (2) their support for agent-to-agent communication, (3) how they allow agents to interact with local resources,
arxiv