Results 281 to 290 of about 210,920 (352)

Accelerated Bone Healing via Electrical Stimulation

Advanced Science, EarlyView.
Electrical stimulation significantly impacts bone healing by enhancing osteoblast proliferation, differentiation, and vascularization through calmodulin/calcineurin/NFAT signaling. It also boosts macrophage function and cell migration, presenting a comprehensive approach to accelerating bone repair.
Jianfeng Sun, Wenqing Xie, Yuxiang Wu, Zhou Li, Yusheng Li   +4 more
wiley   +1 more source

External contamination of commercial containers by antineoplastic agents: a literature review. [PDF]

Eur J Hosp Pharm, 2020
Hilliquin D, Tanguay C, Bussières JF.
europepmc   +1 more source

Targeting Mesothelin Enhances Personalized Neoantigen Vaccine Induced Antitumor Immune Response in Orthotopic Pancreatic Cancer Mouse Models

Advanced Science, Volume 12, Issue 12, March 27, 2025.
Targeting mesothelin (MSLN) improved neoantigen vaccine efficacy in pancreatic cancer by reducing apCAFs, which disrupted the conversion of naive CD4+ T cells into Tregs and enhanced the infiltration of IFN‐γ+CD4+ and GZMK+CD8+ T cells. This combination strengthened neoantigen‐specific T cell response to overcome the immunosuppressive tumor ...
Zhixiong Cai, Zhenli Li, Wenting Zhong, Fangzhou Lin, Xiuqing Dong, Honghao Ye, Yutong Guo, Geng Chen, Xiaoling Yu, Haijun Yu, Ruijing Tang, Xiaolong Liu   +11 more
wiley   +1 more source

Development of the First Value Assessment Index System for Off-Label Use of Antineoplastic Agents in China: A Delphi Study. [PDF]

Front Pharmacol, 2020
Jiang Q, Zeng W, Yu J, Liu H, Mao M, Li Y.   +5 more
europepmc   +1 more source

GRP78 Nanobody‐Directed Immunotoxin Activates Innate Immunity Through STING Pathway to Synergize Tumor Immunotherapy

Advanced Science, EarlyView.
A GRP78 nanobody‐directed immunotoxin suppresses cancer progression and metastasis by enhancing antitumor immunity via STING pathway activation, offering a pan‐cancer‐targeted approach and immunotherapy combination strategy. Abstract The lack of targetable antigens poses a significant challenge in developing effective cancer‐targeted therapies.
Huifang Wang, Runhua Zhou, Chengchao Xu, Lingyun Dai, Rui Hou, Liuhai Zheng, Chunjin Fu, Guangwei Shi, Jingwei Wang, Yang Li, Jinpeng Cen, Xiaolong Xu, Le Yu, Yilei Li, Jigang Wang, Qingfeng Du, Zhijie Li   +16 more
wiley   +1 more source

Tumor Microenvironment‐Driven Structural Transformation of Vanadium‐Based MXenzymes to Amplify Oxidative Stress for Multimodal Tumor Therapy

Advanced Science, Volume 12, Issue 11, March 20, 2025.
This study introduces a novel strategy that uses the TME to trigger structural changes in vanadium carbide MXenzymes, converting them into ultra‐small vanadium oxide nanozymes. These transformations enhance oxidative stress, promoting tumor apoptosis, ferroptosis, and lysosomal permeability.
Hai Zhu, Tinghua Li, Xinhao Peng, Xiaoxian Zhang, Xuequan Zhang, Qiusheng Wang, Lei Lei, Jun Zhang, Bin He, Jun Cao   +9 more
wiley   +1 more source

Computational Analysis of the Effects of Antineoplastic Agents on Axonal Transport

, 2010
Yoshio Goshima, Hiroshi Usui, Takahito Shiozawa, Tomonobu Hida, Satoshi Kuraoka, Sayumi Takeshita, Naoya Yamashita, Yasushi Ichikawa, Yoshinori Kamiya, Takahisa Gotoh, Toshiyuki Gotoh   +10 more
openalex   +2 more sources

Recent Advancements in Lung Cancer Metastasis Prevention Based on Nanostrategies

Advanced Science, EarlyView.
Metastasis is the leading cause of death in patients with lung cancer. Nanomedicine can be used to prepare efficient drug delivery systems owing to their advantages and plays an important role in the synergistic antimetastasis of lung cancer. This comprehensive review summarizes the emerging nanostrategies against lung cancer metastasis based on the ...
Fan Xu, Yao Liu, Zujun Que, Bin Luo, Yun Yang, Yan Li, Zhanxia Zhang, Jianhui Tian   +7 more
wiley   +1 more source

Nanotherapy for Neural Retinal Regeneration

Advanced Science, EarlyView.
Nanotechnology enhances ophthalmic treatments by improving drug delivery and regenerating ocular tissues, combating vision loss from retinal diseases through innovative nano‐systems. This review outlines ocular anatomy, pathology, immune microenvironment, and barriers, detailing nanocarrier characteristics, classification, and preparation methods, and ...
Chuyao Yu, Li Dong, Yujia Lv, Xuhan Shi, Ruiheng Zhang, Wenda Zhou, Haotian Wu, Heyan Li, Yitong Li, Zhou Li, Dan Luo, Wen‐Bin Wei   +11 more
wiley   +1 more source