Results 301 to 310 of about 3,376,621 (386)

Cu(I)‐Catalyzed Interrupted Cycloaddition Between Azides, Ag(I)‐Acetylides, and Diorganoyl Dichalcogenides

Advanced Synthesis &Catalysis, EarlyView.
Unleashing the power of Ag(I)‐acetylides with LiCl/dimethyl sulfoxide (DMSO). The LiCl/DMSO mixture have an unexplored ability to dramatically increase the solubility of Ag(I)‐acetylides regardless of their molecular structure, which is explored to achieve high chemoselectivity in the Cu(I)‐catalyzed interrupted cycloaddition between organic azides, Ag(
Diego Seckler, Eduardo Q. da Luz, Gabriel L. Silvério, Francielli Sousa Santana, Gul Badshah, Wystan K. Teixeira, Caroline R. Montes D’Oca, Ricardo S. Schwab, Daniel S. Rampon   +8 more
wiley   +1 more source

Ultrasensitive Detection of FKBP12 Using a Synthetic Receptor‐Functionalized QCM Nanoplatform

Advanced Sensor Research, EarlyView.
A reusable nanosensor platform for ultralow FKBP12 detection in physiological fluids is presented. Combining a gold‐coated QCM with a custom‐designed receptor in a self‐assembled monolayer, the device achieves picomolar sensitivity and high selectivity.
Martina Tozzetti, Maria Raffaella Martina, Giacomo Lucchesi, Kristian Vasa, Ahtsham Ishaq, Laura Marsili, Piero Procacci, Stefano Menichetti, Gabriella Caminati   +8 more
wiley   +1 more source

Safety of the cancer chemotherapy process in hospital: application to the production of the antineoplastic agents.

, 2007
Brigitte Bonan-Hayat
openalex   +1 more source

Insect‐Microbe‐Based Laccase: Untapped Natural Resource for Industrial and Biotechnological Applications

Advanced Sustainable Systems, EarlyView.
The insect‐microbe interplay fulfills a key ecological role involving the degradation of ligninocellulose biomass. This is coordinated by the secretion of different kinds of proteins, of which ligninolytic enzymes, such as laccases (Lacs), are of prime importance.
Michael Dare Asemoloye, Adeyinka Michael Gbadebo, Tunde Sheriffdeen Bello, Olumayowa Mary Olowe, Akinlolu Olalekan Akanmu, Marta Elisabetta Eleonora Temporiti, Adeyinka Odebode, Segun Oladiran Babarinde, Tsigereda Weldemichael, Leonard Chitongo, Solveig Tosi, Mario Andrea Marchisio   +11 more
wiley   +1 more source

Heterogeneity Landscape of Circulating Tumor Cells in Clinical Utility

Advanced Therapeutics, EarlyView.
This study reports the heterogeneity spectrum of circulating tumor cells. The factors involved in the spectrum promote CTCs to overcome barriers in the metastatic cascade but impact the clinical outcome of cancer patients. In summary, the heterogeneities in association with CTCs ultimately reduce patient survival and facilitate increasing mortality of ...
Md Kowsar Alam, Lu Yanjun, Bee Luan Khoo, Tongxu Si, Heng Zou, Mengsu Yang   +5 more
wiley   +1 more source

Mechanical Interactions Impact the Functions of Immune Cells and Their Application in Immunoengineering

Advanced Therapeutics, EarlyView.
This review covers the mechanical forces experienced by immune cells through cell–cell and cell–extracellular matrix interactions and how these forces influence their receptors and functions. These relationships between forces and cellular functions can be exploited using engineering techniques to modify the physical properties of materials for novel ...
Yu‐Chang Chen, Nghi M. Tran, Kyle H. Vining   +2 more
wiley   +1 more source

Medical Materials and Device Innovation: Choosing the Right and Relevant Biological Models

Advanced Therapeutics, EarlyView.
Choosing the right disease model is key to safe, effective medical innovation. When models reflect human biology and clinical needs, they improve translation, reduce risk, and accelerate progress. Advances in 3D tissues, organ‐on‐chip, and humanized systems offer exciting opportunities. With thoughtful selection and clinician input, biomedical research
Inge K. Herrmann, Tina Buerki‐Thurnherr   +1 more
wiley   +1 more source

Microphysiological Systems in Cancer Research: Advancing Immunotherapy through Tumor Microenvironment‐Integrated Organ‐On‐Chip Models

Advanced Therapeutics, EarlyView.
Emerging microphysiological systems reproduce the spatial, biochemical, and cellular complexity of the tumor microenvironment, surpassing 2D cultures and murine models. By integrating patient‐derived tumors, perfusable vasculature, and immune trafficking, these organ‐on‐chip platforms reveal mechanisms of immune evasion, predict therapeutic responses ...
Fabiana Moresi, Francesco Noto, Jyothsna Vasudevan, Xavier Bisteau, Giulia Adriani, Andrea Pavesi   +5 more
wiley   +1 more source

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Antineoplastic Agents

Antiseizure Medication Interactions, 2016
Cancer is a term used for group of more than 120 distinct diseases that are characterized by the uncontrolled growth of abnormal cells in the body, which are able to invade other tissues, eventually causing death. There are several strategies to treat cancer, including surgery, radiation therapy, immunologic treatment, and chemical-based approaches ...
Ruben Vardanyan, Victor J. Hruby
semanticscholar   +4 more sources

Antineoplastic agents and thrombotic microangiopathy

Journal of Oncology Pharmacy Practice, 2016
Thrombotic microangiopathy is an uncommon but reported adverse effect of a variety of antineoplastic drugs, including chemotherapy agents such as mitomycin C and gemcitabine, and newer targeted agents such as the vascular endothelial growth factor inhibitors.
Jean Paul Atallah, Gwenalyn Garcia
openaire   +3 more sources