Results 31 to 40 of about 3,321,503 (314)

Bioequivalence study between two formulations of 10mg lenalidomide capsules in healthy male subjects under fasting conditions

Brazilian Journal of Oncology, 2023
OBJECTIVE: To evaluate pharmaceutical bioequivalence between two formulations of 10mg lenalidomide capsules in healthy male subjects under fasting conditions.
Carlos Sverdloff, Vinicius Marcondes Rezende, Ligia de Cassia Val, Nelly Cristina Castro, Maria Elena Cedano Limón, Mohammad H. Badii, Sreekanth Kakarla, Murali Pendela, Lygia Bonnato   +8 more
doaj   +1 more source

Antibacterial activities of antineoplastic agents [PDF]

Antimicrobial Agents and Chemotherapy, 1985
Fourteen antineoplastic agents were examined for in vitro antibacterial activity against 101 aerobic and anaerobic bacterial isolates representing indigenous human microflora and selected opportunistic pathogens. Only 5-fluorouracil, mitomycin, and etoposide demonstrated inhibitory effects at achievable plasma concentrations, while the remaining drugs ...
James H. Jorgensen, David J. Drutz, C A Bodet   +2 more
openaire   +3 more sources

Antitumour activity of 1,1-bis-(pyrimidine-2,4-diono-1-il)-2-bromo-2-chloroethylenes substituted molecular complexes and bacterial lectin

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2015
The aim of research. One of the most successful directions of new antitumour preparations finding is the investigation of antimetabolites of pyrimidin’s and purin’s change which forwards as preformed compounds at the link of biosynthetic processes (DNA ...
E. V. Welchinska
doaj   +1 more source

Treatment outcomes for adult patients with localized osteosarcoma treated with chemotherapy without methotrexate at a public hospital in Brazil

Brazilian Journal of Oncology, 2021
Introduction: Standard treatment for pediatric patients with localized osteosarcoma includes high-dose methotrexate (HDMTX), and cure rates greater than 60% are observed.
Marilia Polo Minguete-e-Silva, Renata Rodrigues da Cunha Colombo Bonadio, Gustavo Matos, Diego de Araújo Toloi, Rodrigo Ramella Munhoz, Mirella Nardo, Daniel Rebolledo, Luiz Filipe Marques Correa, Andre Mathias Baptista, Caroline Chaul de Lima Barbosa Zampieri, Olavo Feher, Veridiana Pires de Camargo   +11 more
doaj   +1 more source

Anti-mutagenic and Pro-apoptotic Effects of Apigenin on Human Chronic Lymphocytic Leukemia Cells [PDF]

Acta Medica Iranica, 2010
"nDiet can play a vital role in cancer prevention. Nowadays the scientists are looking for food materials which can potentially prevent the cancer occurrence.
Mehrdad Hashemi, Mehdi Nouri Long, Maliheh Entezari, Shohreh Nafisi, Hossein Nowroozii   +4 more
doaj   +2 more sources

Peritoneal regression grading score (PRGS): first evidence for independent predictive and prognostic significance

Pleura and Peritoneum, 2023
The peritoneal regression grading score (PRGS) is a four-tied pathologic score measuring tumor regression in biopsies from patients with peritoneal metastasis (PM) receiving chemotherapy.
Baake Janina, Nadiradze Giorgi, Archid Rami, Königsrainer Alfred, Bösmüller Hans, Reymond Marc, Solass Wiebke   +6 more
doaj   +1 more source

Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation

FEBS Letters, EarlyView.
Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley   +1 more source

Pharmacotherapy follow‐up of key points in the safety of oral antineoplastic agents

European Journal of Cancer Care, 2017
We assessed the impact of a pharmacotherapy follow-up programme on key safety points [adverse events (AE) and drug administration] in outpatients treated with oral antineoplastic agents (OAA).
V. Escudero-Vilaplana, A. Ribed, R. Romero-Jiménez, A. Herranz-Alonso, M. Sanjurjo-Sáez   +4 more
semanticscholar   +1 more source

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

FEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro, Marco Cellani, Cristina Scielzo   +2 more
wiley   +1 more source

Safe prescription of systemic antineoplastic treatment in oncology: integrative literature review

Brazilian Journal of Oncology, 2022
The objective of this study was to identify the available evidence on the parameters that should be considered to improve the quality and safety of the prescription of systemic antineoplastic treatment.
Fabiola Vasconcelos Alves, Renata Cristina de Campos Pereira Silveira, Flavia Oliveira de Almeida Marques da Cruz, Elaine Barros Ferreira, Paula Elaine Diniz dos Reis   +4 more
doaj   +1 more source