Results 31 to 40 of about 175,055 (304)

Acute kidney injury in critically ill cancer patients : an update [PDF]

, 2016
Patients with cancer represent a growing group among actual ICU admissions (up to 20 %). Due to their increased susceptibility to infectious and noninfectious complications related to the underlying cancer itself or its treatment, these patients ...
Benoit, Dominique, Lameire, Norbert, Van Biesen, Wim, Vanholder, Raymond   +3 more
core   +2 more sources

Strategic Improvement of Oral Antineoplastic Investigational Agents Compliance [PDF]

Global Journal on Quality and Safety in Healthcare, 2019
Background: The use of oral antineoplastic agents has increased in cancer medicine. However, the convenience of oral medication carries the risk of nonadherence and dosing errors, which could jeopardize therapeutic benefits and patient safety.
Anas Alshawa, Jing Gong, Valerie Marcott, Rabia Khan, Valentine Boving, Lakeshia Brown, Jeff Beno, Ed Kheder, Siqing Fu   +8 more
doaj   +1 more source

O-39 CLINICAL CHARACTERISTICS AND OUTCOME OF DRUG-INDUCED LIVER INJURY DUE TO ANTINEOPLASTIC AND BIOLOGICAL AGENTS

Annals of Hepatology, 2023
Introduction and Objectives: Idiosyncratic drug-induced liver injury (DILI) caused by antineoplastic and biological agents is an emerging clinical burden in oncologic patients.
Fernando Bessone, Nelia Hernandez, Raymundo Parana, Maria Isabel Schinoni, Manuel Mendizabal, Adriana Sanchez, Vinicius Nunes, Ezequiel Ridruejo, Daniela Schiodi, Eduardo Fassio, Hugo Tanno, Norberto Tamagnone, Martin Tagle, Pedro Montes, I Medina-Caliz, Mercedes Robles-Díaz, Aida Ortega-Alonso, Miren García-Cortes, Hao Niu, Ismael Alvarez-Alvarez, Rocío Romero-Flores, M Isabel Lucena, Raul J Andrade   +22 more
doaj   +1 more source

Paravasation with cyclophosphamide - Case report of tissue necrosis in a patient with primary breast cancer [PDF]

, 2007
Background: Paravasation is a rare but severe complication of treatment with cytotoxic agents. Some anticancer drugs are considered to be of high toxicity (vesicant), some are merely irritant, and some are regarded as nearly non-toxic to healthy tissue ...
Adami NP, Bertelli G, Boyle DM, Dorr RT, Goolsby TV, Jordan K, Reich B, Tsavaris NB   +7 more
core   +1 more source

Transcriptional inhibition of type I collagen gene expression in scleroderma fibroblasts by the antineoplastic drug ecteinascidin 743. [PDF]

, 2003
We previously showed that COL1A1 expression is up-regulated at the transcriptional level in systemic sclerosis (SSc) fibroblasts and that the CCAAT-binding factor (CBF) is involved in this increased expression.
Herrick, David J, Jimenez, Sergio A., Louneva, Natalia, Saitta, Biagio   +3 more
core   +2 more sources

Antitumour activity of 1,1-bis-(pyrimidine-2,4-diono-1-il)-2-bromo-2-chloroethylenes substituted molecular complexes and bacterial lectin

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2015
The aim of research. One of the most successful directions of new antitumour preparations finding is the investigation of antimetabolites of pyrimidin’s and purin’s change which forwards as preformed compounds at the link of biosynthetic processes (DNA ...
E. V. Welchinska
doaj   +1 more source

Testicular cancer and sperm DNA damage: short- and long-term effects of antineoplastic treatment [PDF]

, 2015
The aim of this study was to investigate sperm DNA damage induced by chemo- and radiotherapy in patients with testicular cancer to provide data on the extent and persistence of nuclear damage that might affect individual reproductive potential.
F. Rizzo, G. Leter, GALLO, MARIAGRAZIA, GANDINI, Loredana, LENZI, Andrea, LOMBARDO, Francesco, M. Spano, PAOLI, Donatella   +7 more
core   +1 more source

EFFICACY OF PROBIOTICS IN PREVENTING CHEMOTHERAPY-INDUCED DIARRHEA IN GASTROINTESTINAL CANCER PATIENTS [PDF]

Arquivos de Gastroenterologia
Background: Chemotherapy-induced diarrhea is a common and distressing side effect experienced by patients undergoing cancer treatment, particularly those with gastrointestinal cancer. It can lead to significant health complications, including dehydration,
Gabriel Caio DE SOUZA, Humberto Bezerra de Araujo FILHO, Cleyton Zanardo DE OLIVEIRA, Ana Paula Ribeiro PAIOTTI, Nora Manoukian FORONES   +4 more
doaj   +1 more source

Docking-based virtual screening of known drugs against murE of Mycobacterium tuberculosis towards repurposing for TB. [PDF]

, 2016
Repurposing has gained momentum globally and become an alternative avenue for drug discovery because of its better success rate, and reduced cost, time and issues related to safety than the conventional drug discovery process.
Brindha, Sridharan, Gnanadoss, John Joel, Sundaramurthi, Jagadish Chandrabose, Velmurugan, Devadasan, Vincent, Savariar   +4 more
core   +1 more source

Drosophila modifier screens to identify novel neuropsychiatric drugs including aminergic agents for the possible treatment of Parkinson's disease and depression. [PDF]

, 2014
Small molecules that increase the presynaptic function of aminergic cells may provide neuroprotection in Parkinson's disease (PD) as well as treatments for attention deficit hyperactivity disorder (ADHD) and depression.
Biedermann, T, Chou, M-T, Djapri, C, Hadi, R, Huang, B, Jang, J, Krantz, DE, Lam, HA, Lawal, HO, Lawless, GM, Maidment, NT, Roberts, L, Shahi, V, Terrell, A   +13 more
core   +2 more sources