Results 21 to 30 of about 288,402 (222)
Gestational trophoblastic disease [PDF]
Archive of Oncology, 2002 Gestational trophoblastic disease belongs to a spectrum of rare tumors originating from trophoblast. It spreads from the benignant disease uncomplicated partial mole to the most malignant choriocarcinoma in stage IV of disease with brain metastases ...
Živaljević Milica +4 more
doaj +1 more source
Enhancement of chemotherapy using oncolytic virotherapy: Mathematical and optimal control analysis [PDF]
Math. Biosci. Eng. 15 (2018), no. 6, 1435--1463, 2018 Oncolytic virotherapy (OV) has been emerging as a promising novel cancer treatment that may be further combined with the existing therapeutic modalities to enhance their effects. To investigate how OV could enhance chemotherapy, we propose an ODE based model describing the interactions between tumour cells, the immune response, and a treatment ...
arxiv +1 more source
Xeloda as first-line therapy of metastatic colorectal cancer-our experience [PDF]
Archive of Oncology, 2002 BACKGROUND: Results of phase III clinical studies comparing efficacy of Xeloda vs. standard 5-FU/FA protocols as first line therapy of metastatic colorectal carcinoma (MCRC), have shown better efficacy of Xeloda, with less toxic adverse effects, apart ...
Kovčin Vladimir +4 more
doaj +1 more source
The role of dose-density in combination cancer chemotherapy [PDF]
, 2019 A multicompartment mathematical model is presented with the goal of studying the role of dose-dense protocols in the context of combination cancer chemotherapy. Dose-dense protocols aim at reducing the period between courses of chemotherapy from three to two weeks or less, in order to avoid the regrowth of the tumor during the meantime and achieve ...
arxiv +1 more source
Combination Chemotherapy Optimization with Discrete Dosing [PDF]
arXiv, 2021 Chemotherapy is one of the primary modalities of cancer treatment. Chemotherapy drug administration is a complex problem that often requires expensive clinical trials to evaluate potential regimens. One way to alleviate this burden and better inform future trials is to build reliable models for drug administration.
arxiv
Use of gemtuzumab ozogamycin combined with conventional chemotherapy in patients with acute myeloid leukemia [PDF]
Einstein (São Paulo), 2011 Objective: To analyze the outcome of patients treated with gemtuzumab ozogamycin combined with conventional therapy treated at Hospital Israelita Albert Einstein.
Guilherme Fleury Perini +9 more
doaj +3 more sources
Compliance with a protocol for acute lymphoblastic leukemia in childhood
Revista Brasileira de Hematologia e Hemoterapia, 2011 BACKGROUND: Remission rates achieved after the initial treatment of acute lymphoblastic leukemia may be similar in both developed and developing countries, but relapse rates are much higher in the latter.
Benigna Maria de Oliveira +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Pancreatic ductal adenocarcinoma (PDAC) is a disease with very poor prognosis due to therapeutic limitations. We investigated the antitumor effects of cystatin A (CSTA) in PDAC murine models. We are first to confirm that CSTA enhances T helper type 1‐mediated antitumor effects through promotion of dendritic cells and M1 macrophage activity. CSTA can be
Alessandro Nasti +8 more
wiley +1 more source
Isolated eyeball metastasis of non-seminomatous germ cell testicular tumor [PDF]
Vojnosanitetski Pregled, 2011 Introduction. Testicular tumors most frequently metastasize to regional lymph nodes. Non-seminomatous tumor metastasis of testicle (NSGCTT) to the eyeball is rare. Case report.
Bojanić Nebojša +5 more
doaj +1 more source
Mathematical Model of the Impact of Chemotherapy and Anti-Angiogenic Therapy on Drug Resistance in Glioma Growth [PDF]
arXiv, 2023 This research presents a mathematical model of glioma growth dynamics with drug resistance, capturing interactions among five cell populations: glial cells, sensitive glioma cells, resistant glioma cells, endothelial cells, and neuron cells, along with two therapy agent populations: chemotherapy and anti-angiogenic therapy.
arxiv