Results 1 to 10 of about 1,839,583 (268)

Drug therapies in dermatology [PDF]

open access: yesClinical Medicine, 2014
This article explores the current and emerging therapies for skin disease, with a particular focus on chronic plaque psoriasis and metastatic malignant melanoma. We discuss the current biological therapies used for psoriasis and those on the horizon, including small molecules and biosimilars.
Aslam, Arif, Griffiths, Christopher E M
openaire   +3 more sources

Approaches to Improve EPR-Based Drug Delivery for Cancer Therapy and Diagnosis

open access: yes, 2023
The innovative development of nanomedicine has promised effective treatment options compared to the standard therapeutics for cancer therapy. However, the efficiency of EPR-targeted nanodrugs is not always pleasing as it is strongly prejudiced by the ...
Farzana Parveen   +4 more
core   +1 more source

Self-Initiation of Antiretroviral Therapy in the Developing World: the Involvement of Private Pharmacies in an HIV Program. [PDF]

open access: yes, 2012
Self-initiation to antiretroviral treatment (ART) exposes the patient to the risk of drug toxicity, poor adherence to treatment, and escalates the development of drug resistance.
Buma, Deus   +8 more
core   +1 more source

Characterizing the emergence and persistence of drug resistant mutations in HIV-1 subtype C infections using 454 ultra deep pyrosequencing. [PDF]

open access: yes, 2013
BACKGROUND: The role of HIV-1 RNA in the emergence of resistance to antiretroviral therapies (ARTs) is well documented while less is known about the role of historical viruses stored in the proviral DNA. The primary focus of this work was to characterize
Grace P McCormack   +21 more
core   +1 more source

Nanomaterials for Drug Delivery and Cancer Therapy

open access: yes, 2023
This reprint of “Nanomaterials for Drug Delivery and Cancer Therapy” covers the recent advances in the use of nanoparticle systems, with an emphasis on preparation and characterization methods, functionalization chemistry, and their associated ...

core   +2 more sources

AtriplaR/anti-TB Combination in TB/HIV Patients. Drug in Focus. [PDF]

open access: yes, 2011
Co-administration of anti-tuberculosis and antiretroviral therapy is often inevitable in high-burden countries where tuberculosis is the most common opportunistic infection associated with HIV/AIDS. Concurrent use of rifampicin and several antiretroviral
Semvua Hadija H   +5 more
core   +1 more source

Drug resistance with monitored adherence [PDF]

open access: yes, 2013
Drug resistance can be defined as the failure of a drug to exert its expected effect on pharmacological biomarkers and is caused by pharmacogenetic, cellular or clinical factors.
Walter, Philipp Niklaus
core   +1 more source

Systems analysis of drug-induced receptor tyrosine kinase reprogramming following targeted mono- and combination anti-cancer therapy [PDF]

open access: yes, 2014
The receptor tyrosine kinases (RTKs) are key drivers of cancer progression and targets for drug therapy. A major challenge in anti-RTK treatment is the dependence of drug effectiveness on co-expression of multiple RTKs which defines resistance to single ...
Goltsov, Alexey   +27 more
core   +1 more source

Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration [PDF]

open access: yes, 2005
Background The genetic differences among HIV-1 subtypes may be critical to clinical management and drug resistance surveillance as antiretroviral treatment is expanded to regions of the world where diverse non-subtype-B viruses predominate.Methods and ...
Wynhoven, B   +61 more
core   +1 more source

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