Results 21 to 30 of about 2,964,728 (312)

Antiobesity drug therapy [PDF]

Cleveland Clinic Journal of Medicine, 2021
To the Editor : The article by Mauer et al[1][1] in the August issue is an excellent and comprehensive review of antiobesity pharmacologic therapy. The authors twice mention the positive impact of antiobesity medications in reducing blood pressure.
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Geriatric pharmacotherapy : optimisation through integrated approach in the hospital setting [PDF]

, 2016
Since older patients are more vulnerable to adverse drug-related events, there is a need to ensure appropriate prescribing in these patients in order to prevent misuse, overuse and underuse of drugs.
A Corsonello, A Jha, A Leendertse, A Somers, A Somers, A Somers, A Spinewine, A Spinewine, A Spinewine, American Geriatrics Society, B Basger, B Berenguer, B Lund, B Strom, B Tangiisuran, C Lindley, C Naugler, C Rancourt, C Scullin, C Zhan, D Classen, E Hajjar, G Batty, G Ellis, G Onder, G Onder, G Onder, G Onder, H Beijer, H Hamilton, I Eland, J Hanlon, J Hanlon, J Klopotowska, J Lazarou, J Schnipper, J Wolfstadt, K Perehudoff, K Schmader, L Leape, M Beers, M Laroche, M O’Connor, M Passarelli, M Petrovic, M Petrovic, M Pirmohamed, M Steinman, NS Wenger, P Bemt van den, P Gallagher, P Gallagher, P Lampela, P McLeod, P Rochon, R Cipolle, R Page, S Holt, S Kaur, S Kucukarslan, S Rognstad, T Field, T Field, W Winit-Watjana   +63 more
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Mycobacteriophages in diagnosis and alternative treatment of mycobacterial infections

Frontiers in Microbiology, 2023
Antimicrobial resistance is an increasing threat to human populations. The emergence of multidrug-resistant “superbugs” in mycobacterial infections has further complicated the processes of curing patients, thereby resulting in high morbidity and ...
Xudong Ouyang, Xudong Ouyang, Xiaotian Li, Xiaotian Li, Jinmiao Song, Jinmiao Song, Hui Wang, Hui Wang, Shuxian Wang, Shuxian Wang, Ren Fang, Ren Fang, Zhaoli Li, Ningning Song, Ningning Song   +14 more
doaj   +1 more source

A Cross-Sectional Study Comparing the Frequency of Drug Interactions After Adding Simeprevir- or Sofosbuvir-Containing Therapy to Medication Profiles of Hepatitis C Monoinfected Patients. [PDF]

, 2015
INTRODUCTION:This study compares the expected occurrence of contraindicated drug-drug interactions (XDDIs) when simeprevir (SIM)- or sofosbuvir (SOF)-containing therapy is added to medication profiles of patients with hepatitis C (HCV) monoinfection to ...
Bliss, Steven, Davis, Melissa, Koroglu, Arden, McNutt, Louise-Anne, Miller, Christopher, Nasiri, Mona, Patel, Nimish   +6 more
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Patient and Disease-Specific Induced Pluripotent Stem Cells for Discovery of Personalized Cardiovascular Drugs and Therapeutics. [PDF]

, 2020
Human induced pluripotent stem cells (iPSCs) have emerged as an effective platform for regenerative therapy, disease modeling, and drug discovery.
Chandy, Mark, Paik, David T, Wu, Joseph C   +2 more
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Enhancing TB Vaccine Efficacy: Current Progress on Vaccines, Adjuvants and Immunization Strategies

Vaccines, 2023
Tuberculosis (TB) remains a global infectious disease primarily transmitted via respiratory tract infection. Presently, vaccination stands as the primary method for TB prevention, predominantly reliant on the Bacillus Calmette–Guérin (BCG) vaccine ...
Hui Wang, Shuxian Wang, Ren Fang, Xiaotian Li, Jiayin Xing, Zhaoli Li, Ningning Song   +6 more
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Ligation of anti-cancer drugs to self-assembling ultrashort peptides by click chemistry for localized therapy [PDF]

, 2013
Self-assembling ultrashort peptides from aliphatic amino acids were functionalized with platinum anti-cancer drugs by click chemistry. Oxaliplatin-derived hybrid peptide hydrogels with up to 40% drug loading were tested for localized breast cancer ...
Chan, Kiat-Hwa, Gopalan, Began, Hauser, Charlotte A. E., Joshi, Mangesh, Lakshmanan, Anupama, Lam, Dang Hoang, Mishra, Archana, Reithofer, Michael R., Wang, Shu   +8 more
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Folate-conjugated nanoparticles as a potent therapeutic approach in targeted cancer therapy [PDF]

, 2015
The selective and efficient drug delivery to tumor cells can remarkably improve different cancer therapeutic approaches. There are several nanoparticles (NPs) which can act as a potent drug carrier for cancer therapy.
Bahrami, B., Bakhshaei, P., Ghalamfarsa, G., Hojjat-Farsangi, M., Jadidi-Niaragh, F., Mohammadnia-Afrouzi, M., Sadreddini, S., Yazdani, Y., Yousefi, M.   +8 more
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Comparative analysis of CDR3 length-dependent patterns in VHHs

Frontiers in Immunology
IntroductionVHHs, or nanobodies, are distinguished by their compact size, high stability, and unique ability to selectively target specific epitopes. The CDR3 region in VHHs, which plays a crucial role in antigen binding, exhibits significant diversity ...
Lu Zhang, Tianyu Yang, Yao Zhang, Jiahui Yan, Jiaguo Li, Wenfeng Xu, Weimin Zhu, Xinhao Wang   +7 more
doaj   +1 more source

Antihypertensive drug therapy [PDF]

Annals of Translational Medicine, 2018
Lifestyle measures plus antihypertensive drug therapy should be used to treat adults with hypertension (1-4). Adults with clinical cardiovascular disease (coronary heart disease, heart failure, and stroke) should have their blood pressure reduced below 130/80 mmHg for secondary prevention of recurrent cardiovascular disease events (4).
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