Results 131 to 140 of about 12,382 (173)
Some of the next articles are maybe not open access.
Testing for antineutrophil cytoplasmic antibodies
Expert Review of Molecular Diagnostics, 2001The most common reason to request a test for antineutrophil cytoplasmic antibodies (ANCA) is to diagnose Wegener's granulomatosis and microscopic polyangiitis and to monitor inflammatory activity in these diseases. Several retrospective and prospective studies have suggested that the demonstration of ANCA lacks sensitivity and specificity, but these ...
openaire +2 more sources
Antineutrophil cytoplasmic antibodies
American Journal of Medicine, 1992Antineutrophil cytoplasmic antibodies (ANCA) have been described as sensitive and specific markers for active Wegener's granulomatosis (WG). ANCA in WG produce a characteristic cytoplasmic staining pattern of neutrophils (c-ANCA) and are directed against proteinase 3 (Pr3), a serine protease from the azurophilic granules.
Kallenberg, Cees G. M. +2 more
openaire +1 more source
Antineutrophil cytoplasmic antibodies (ANCA) and vasculitis
Clinical Rheumatology, 1990The demonstration of autoantibodies to different myeloid lysozomal enzymes has opened a new area for the study of vasculitic syndromes. Autoantibodies producing a granular cytoplasmic staining by IIF (c-ANCA, probably directed to a putative serine protease) are closely associated with Wegener's granulomatosis.
openaire +3 more sources
Antineutrophil cytoplasmic antibodies and their relevance to the dermatologist
British Journal of Dermatology, 2006The term vasculitis embraces a heterogeneous group of conditions which may occur as primary phenomena or secondary to disorders such as rheumatoid arthritis or systemic lupus erythematosus. Classification of vasculitis is often difficult in the absence of identifiable aetiological factors or specific serological markers.
N P, Burrows, C M, Lockwood
openaire +2 more sources
Antineutrophil Cytoplasmic Antibodies Testing and Interpretation
Clinics in Laboratory Medicine, 2019The discovery of antineutrophil cytoplasmic antibodies (ANCA) helped establish ANCA-associated vasculitis as a separate and well-defined clinical entity. Its progressive incorporation into the clinical diagnosis algorithms has made ANCA testing a cornerstone immunoassay embedded in the management of ANCA-associated vasculitis.
Hugues, Allard-Chamard, Patrick, Liang
openaire +2 more sources
Clinical value of antineutrophil cytoplasmic antibodies
Current Rheumatology Reports, 2000This article presents a brief review of the clinical value of antineutrophil cytoplasmic antibodies (ANCA) in the diagnosis and management of patients with various forms of vasculitis. ANCA assay methodology and testing recommendations are reviewed. The patterns of reactivity of ANCA observed by indirect immunofluorescence, the antigens recognized by ...
V, Rus, B S, Handwerger
openaire +2 more sources
Antineutrophil Cytoplasmic Antibodies in Diffuse Panbronchiolitis
Respiration, 1999<i>Background:</i> There are some reports of the coexistence of chronic suppurative lung diseases such as cystic fibrosis and systemic vasculitis. Diffuse panbronchiolitis has the same characteristics as chronic recurrent sinopulmonary infection and respiratory bronchiolitis.
Y, Sugiyama, S, Kitamura
openaire +2 more sources
The antineutrophil cytoplasmic antibody–associated vasculitides
The American Journal of Medicine, 2004Wegener's granulomatosis, microscopic polyangiitis, and Churg-Strauss syndrome are small- to medium-vessel vasculitides linked by overlapping pathology and the presence of antineutrophil cytoplasmic antibodies (ANCA). Commonly referred to as the ANCA-associated vasculitides, these diseases are challenging to diagnose and to treat.
Philip, Seo, John H, Stone
openaire +2 more sources
Antineutrophil cytoplasmic antibody-associated neutropenia
European Journal of Internal Medicine, 2004BACKGROUND: Antineutrophil cytoplasmic antibodies (ANCA) can be associated with various disorders. However, their association with neutropenia has never been reported. METHODS: Nine patients with chronic unexplained neutropenia and ANCA were studied. Clinical charts were extensively analyzed and all patients underwent hematological and immunological ...
Paul, Coppo +7 more
openaire +2 more sources
Antineutrophil cytoplasmic antibody-associated vasculitis
Current Opinion in Nephrology & HypertensionPurpose of review This review focuses on latest developments in managing antineutrophil cytoplasmic autoantibody (ANCA)-associated vasculitis (AAV), a systemic autoimmune condition characterized by inflammation and necrosis of small blood vessels due to circulating autoantibodies that target neutrophilic granules.
Raghunandan, Konda +2 more
openaire +2 more sources