Results 181 to 190 of about 17,551 (206)

Antineutrophil cytoplasmic antibody-associated vasculitis

Current Opinion in Nephrology & Hypertension
Purpose of review This review focuses on latest developments in managing antineutrophil cytoplasmic autoantibody (ANCA)-associated vasculitis (AAV), a systemic autoimmune condition characterized by inflammation and necrosis of small blood vessels due to circulating autoantibodies that target neutrophilic granules.
Raghunandan, Konda, Arun, Rajasekaran, Dana V, Rizk   +2 more
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The antineutrophil cytoplasmic antibody–associated vasculitides

The American Journal of Medicine, 2004
Wegener's granulomatosis, microscopic polyangiitis, and Churg-Strauss syndrome are small- to medium-vessel vasculitides linked by overlapping pathology and the presence of antineutrophil cytoplasmic antibodies (ANCA). Commonly referred to as the ANCA-associated vasculitides, these diseases are challenging to diagnose and to treat.
Philip, Seo, John H, Stone
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Testing for antineutrophil cytoplasmic antibodies

Expert Review of Molecular Diagnostics, 2001
The most common reason to request a test for antineutrophil cytoplasmic antibodies (ANCA) is to diagnose Wegener's granulomatosis and microscopic polyangiitis and to monitor inflammatory activity in these diseases. Several retrospective and prospective studies have suggested that the demonstration of ANCA lacks sensitivity and specificity, but these ...
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Antineutrophil cytoplasmic antibody-associated vasculitides

Joint Bone Spine, 2007
The identification of antineutrophil cytoplasmic antibodies (ANCA) proved a major breakthrough in the classification, diagnosis, monitoring, and understanding of vasculitides. Vasculitides associated with ANCA selectively affect the small vessels; they include Wegener granulomatosis, microscopic polyangiitis, and Churg-Strauss syndrome.
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Childhood antineutrophil cytoplasmic antibodies associated vasculitides

Current Opinion in Rheumatology, 2014
The purpose of this review is to discuss the most recent published literature in childhood antineutrophil cytoplasmic antibodies (ANCA) associated vasculitides and to identify the important issues arisen in the adult literature. This review will discuss the literature on new treatment regimens and outcome measurements.Antineutrophil cytoplasmic ...
Marinka, Twilt, Susanne, Benseler
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Antineutrophil Cytoplasmic Antibody–Associated Lung Fibrosis

Seminars in Respiratory and Critical Care Medicine, 2018
AbstractPulmonary fibrosis is observed in a substantial number of patients with ANCA-associated vasculitis (AAV), 15% in a recent German series, and may be more frequent in Asian populations. ANCA are usually of anti-MPO specificity and microscopic polyangiitis is the most frequent vasculitis.
Raphael, Borie, Bruno, Crestani
openaire   +2 more sources

Antineutrophil cytoplasmic antibodies (ANCA) and vasculitis

Clinical Rheumatology, 1990
The demonstration of autoantibodies to different myeloid lysozomal enzymes has opened a new area for the study of vasculitic syndromes. Autoantibodies producing a granular cytoplasmic staining by IIF (c-ANCA, probably directed to a putative serine protease) are closely associated with Wegener's granulomatosis.
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Antineutrophil Cytoplasmic Antibodies in Diffuse Panbronchiolitis

Respiration, 1999
<i>Background:</i> There are some reports of the coexistence of chronic suppurative lung diseases such as cystic fibrosis and systemic vasculitis. Diffuse panbronchiolitis has the same characteristics as chronic recurrent sinopulmonary infection and respiratory bronchiolitis.
Y, Sugiyama, S, Kitamura
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Antineutrophil Cytoplasmic Antibodies Testing and Interpretation

Clinics in Laboratory Medicine, 2019
The discovery of antineutrophil cytoplasmic antibodies (ANCA) helped establish ANCA-associated vasculitis as a separate and well-defined clinical entity. Its progressive incorporation into the clinical diagnosis algorithms has made ANCA testing a cornerstone immunoassay embedded in the management of ANCA-associated vasculitis.
Hugues, Allard-Chamard, Patrick, Liang
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Clinical value of antineutrophil cytoplasmic antibodies

Current Rheumatology Reports, 2000
This article presents a brief review of the clinical value of antineutrophil cytoplasmic antibodies (ANCA) in the diagnosis and management of patients with various forms of vasculitis. ANCA assay methodology and testing recommendations are reviewed. The patterns of reactivity of ANCA observed by indirect immunofluorescence, the antigens recognized by ...
V, Rus, B S, Handwerger
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