Results 41 to 50 of about 626,304 (143)

Targeting neutrophil extracellular traps in metabolic and immune niche: Nanomaterials for diabetes tissue regeneration

BMEMat, EarlyView.
The effects of NETs on regeneration of various diabetic tissues, and strategies targeting NETs for diabetes tissue regeneration. In the diabetic environment, NETs undergo complex metabolic and immune reprogramming, leading to dynamic changes in antibacterial and proinflammatory functions, and affecting regeneration of multiple systemic tissues.
Xinyi Jiang, Muxin Yue, Kai Mao, Boon Chin Heng, Noor Azlin Yahya, Yunsong Liu, Zheng Li   +6 more
wiley   +1 more source

Antineutrophil cytoplasmic antibodies in inflammatory bowel disease: Clinical role and review of the literature

, 2000
PURPOSE: Perinuclear antineutrophil cytoplasmic antibodies have been found consistently in patients with ulcerative colitis; however, their pathogenetic and clinical role is still uncertain.
Lombardi G., Andriulli A., Piepoli A., Perri F., Bovio P., Annese V., Latiano A., Napolitano G., Conoscitore P.   +8 more
core   +1 more source

Cytoplasmic islet cell antibodies recognize distinct islet antigens in IDDM but not in stiff man syndrome [PDF]

, 1993
Cytoplasmic islet cell antibodies are well-established predictive markers of IDDM. Although target molecules of ICA have been suggested to be gangliosides, human monoclonal ICA of the immunoglobulin G class (MICA 1-6) produced from a patient with newly ...
Seißler, Jochen, Meinck, Hans-Michael, Wolfahrt, S., Northemann, Wolfgang, Scherbaum, Werner A., Richter, Wiltrud   +5 more
core   +1 more source

Pediatric Inflammatory Bowel Disease with Cytoplasmic Staining of Antineutrophil Cytoplasmic Antibodies

Clinical and Developmental Immunology, 2013
Background. It is unusual for the antineutrophil cytoplasmic antibody with cytoplasmic pattern (cANCA) to present in patients with inflammatory bowel disease (IBD) without vasculitis.
Omar I. Saadah, Jamil A. Al-Mughales
doaj   +1 more source

Cytoplasmic-anti-neutrophil cytoplasmic antibodies targeting myeloperoxidase in Wegener′s granulomatosis: A rare phenomenon

Indian Journal of Pathology and Microbiology, 2014
Wegener′s granulomatosis (WG) patients can rarely have antineutrophil cytoplasmic antibodies (ANCAs) directed against myeloperoxidase (MPO), producing a cytoplasmic pattern on indirect immunofluorescence (IIF).
Bhavana M Venkatesh, Sangeeta Joshi, Ranjeeta Adhikary   +2 more
doaj   +1 more source

Granulomatosis with Polyangiitis Misdiagnosed as IgA Vasculitis in a Child

Case Reports in Pediatrics, 2023
Background. Granulomatosis with polyangiitis (GPA) with early manifestations simulating IgA vasculitis is a very rare childhood systemic disease. Case Presentation.
Sheida Amini, Mohsen Jari
doaj   +1 more source

Eosinophilia and Hypereosinophilia: A Practical Approach to Navigating a Broad Differential Diagnosis

European Journal of Haematology, EarlyView.
ABSTRACT Eosinophilia, defined as an absolute eosinophil count (AEC) of ≥ 0.5 × 109/L, is a frequently encountered finding with a vast spectrum of potential underlying etiologies. Hypereosinophilia (HE) is defined as AEC > 1.5 × 109/L and may become life‐threatening when eosinophil‐induced organ damage occurs, defining the hypereosinophilic syndrome ...
Stijn Wigerinck, Peter Vandenberghe
wiley   +1 more source

Anti‐Integrin αvβ6 Autoantibodies as Diagnostic and Monitoring Biomarkers for Pediatric‐Onset Primary Sclerosing Cholangitis

Hepatology Research, EarlyView.
Levels of anti‐integrin αvβ6 antibodies were significantly higher in pediatric‐onset primary sclerosing cholangitis (PSC) than in autoimmune hepatitis (AIH) and may reflect disease activity. These antibodies may serve as a novel biomarker for distinguishing PSC from AIH and for monitoring disease progression.
Yukako Maeda, Shuichiro Umetsu, Eitaro Hiejima, Mitsuyoshi Suzuki, Itaru Iwama, Takeshi Kimura, Sonoko Kondo, Ayano Inui, Hiroki Kondou, Tatsuya Okamoto, Takashi Ito, Hiroyuki Shirahase, Kazushi Izawa, Takahiro Yasumi, Takeshi Kuwada, Masahiro Shiokawa, Hiroshi Seno, Junko Takita   +17 more
wiley   +1 more source

Antineutrophil cytoplasmic antibodies in chronic liver diseases: prevalence, titre, specificity and IgG subclass.

, 1996
BACKGROUND/AIMS: Antineutrophil cytoplasmic antibodies are reported in patients with chronic liver disease, but controversy exists about their prevalence and specificity.
Chapman, Roger, Devinder Bansi, Kenneth Fleming, Chapman, R, Roger Chapman, Bansi, D, Fleming, K   +6 more
core   +1 more source

ANTINEUTROPHIL CYTOPLASMIC ANTIBODIES LEVELS IN THE PATIENTS WITH FAMILIAL MEDITERRANEAN FEVER DURING ACUTE ATTACK

Eurasian Journal of Medicine, 2019
Antineutrophil cytoplasmic antibodies (ANCA) are autoantibodies directed at lysosomal constituens of leucocytes, with two major immunufluoresence stainig patterns: cytoplasmic (c-ANCA), and perinuclear (p-ANCA).
Ali Rıza Odabaş, Ramazan Çetinkaya, Yılmaz Selçuk   +2 more
doaj