Results 11 to 20 of about 13,222 (178)

The role of the host—Neutrophil biology

Periodontology 2000, EarlyView., 2023
Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple, Josefine Hirschfeld, Alpdogan Kantarci, Asaf Wilensky, Lior Shapira   +4 more
wiley   +1 more source

Massive Alveolar Haemorrhage Presenting During the COVID-19 Pandemic

European Medical Journal Respiratory, 2021
The coronavirus disease (COVID-19) pandemic has challenged healthcare systems and has resulted in complex diagnostic processes for patients with non-COVID-19 pathology.
Joseph Page, Caitlin Morgan, John Hughes, Janet Fallon   +3 more
doaj   +1 more source

Antineutrophil cytoplasmic antibodies: appropriate use and interpretation [PDF]

Annals of the Rheumatic Diseases, 2017
It was with much interest that we read the letter of Novikov et al 1 on testing for antineutrophil cytoplasmic antibodies (ANCAs) in patients with ANCA-associated vasculitides (AAV) and other diseases. In their letter, the authors (1) share their experience with direct testing for proteinase-3 (PR3) ANCA and myeloperoxidase (MPO) ANCA and (2) raise ...
Damoiseaux, Jan, Csernok, Elena, Rasmussen, Niels, Tervaert, Jan-Willem Cohen, Bossuyt, Xavier   +4 more
openaire   +2 more sources

Deep vein thrombosis: An unusual way of revealing microscopic polyangiitis. Deep vein thrombosis in microscopic polyangiitis

Clinical Case Reports, 2021
Unexplained deep vein thrombosis may justify screening for antineutrophil cytoplasmic antibody‐associated vasculitis as it can be an unusual presentation of this disease.
Mouna Jerbi, Hiba Ghabi, Hanene Gaied, Mariem Khadhar, Raja Aoudia, Rim Goucha, Taieb Ben Abdallah   +6 more
doaj   +1 more source

Acute tubulointerstitial nephritis associated with antineutrophil cytoplasmic antibody following cimetidine treatment: a case report

BMC Nephrology, 2021
Background Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis usually induces rapidly progressive glomerulonephritis, including pauci-immune necrotizing crescentic glomerulonephritis.
Keita Morimoto, Go Kanzaki, Takahito Niikura, Kentaro Koike, Nanae Matsuo, Yukio Maruyama, Nobuo Tsuboi, Takashi Yokoo   +7 more
doaj   +1 more source

Hydralazine-induced antineutrophil cytoplasmic antibody-associated vasculitis with pulmonary–renal syndrome: a case report

Journal of Medical Case Reports, 2020
Background Hydralazine is a common vasodilator which has been used for the treatment of hypertension and heart failure. Hydralazine can induce antineutrophil cytoplasmic antibody-associated vasculitis due to its auto-immunogenic capability and one of the
Ahmad Al-Abdouh, Abdul Muhaymin Siyal, Hanan Seid, Ammer Bekele, Pablo Garcia   +4 more
doaj   +1 more source

Antineutrophil cytoplasmic antibodies: reporting and diagnostic strategies [PDF]

Annals of the Rheumatic Diseases, 2017
It was with great interest that we read the correspondence of Mahler and Fritzler1 on our recent European Vasculitis Study Group (EUVAS) study describing the performance of immunoassays for antineutrophil cytoplasmic antibodies (ANCA) in patients with ANCA-associated vasculitides (AAV).2 In their letter, Mahler and Fritzler raise some interesting ...
Damoiseaux, Jan, Csernok, Elena, Rasmussen, Niels, Tervaert, Jan-Willem Cohen, Bossuyt, Xavier   +4 more
openaire   +3 more sources

Antineutrophil cytoplasmic antibodies

Reumatismo, 2011
Antineutrophil cytoplasmic antibodies (ANCA) are predominantly IgG autoantibodies directed against constituents of primary granules of neutrophils and monocytes lysosomes. Although several antigenic targets have been identified, those ANCA directed to proteinase 3 or myeloperoxidase are clinically relevant, whereas the importance of other ANCA remains ...
openaire   +5 more sources

Antineutrophil cytoplasmic antibodies (ANCA)

Autoimmunity, 2005
Antineutrophil cytoplasmic antibodies (ANCA) are a sensitive and specific marker for ANCA-associated systemic vasculitis. Using indirect immunofluorescence on ethanol-fixed neutrophils, two major fluoroscopic patterns can be recognised: a diffuse cytoplasmic staining (C-ANCA), and a perinuclear/nuclear staining (P-ANCA).
Radice, A, SINICO, RENATO ALBERTO
openaire   +2 more sources

Proteinase 3-antineutrophil cytoplasmic antibody-positive necrotizing crescentic glomerulonephritis complicated by infectious endocarditis: a case report

Journal of Medical Case Reports, 2019
Background Proteinase 3-antineutrophil cytoplasmic antibody has been reported to be positive in 5–10% of cases of renal injury complicated by infective endocarditis; however, histological findings have rarely been reported for these cases.
Katsunori Yanai, Yoshio Kaku, Keiji Hirai, Shohei Kaneko, Saori Minato, Yuko Mutsuyoshi, Hiroki Ishii, Taisuke Kitano, Mitsutoshi Shindo, Haruhisa Miyazawa, Kiyonori Ito, Yuichiro Ueda, Masahiro Hiruta, Susumu Ookawara, Yoshihiko Ueda, Yoshiyuki Morishita   +15 more
doaj   +1 more source