Results 81 to 90 of about 697,296 (219)

Antineutrophil cytoplasmic antibody-associated vasculitis in a patient with diffuse scleroderma

, 2021
Scleroderma is a multiorgan connective tissue disease characterized by autoantibody production and fibroproliferative stenosis of the microvasculature. The development of antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis in patients with ...
H A Karthik Urala, B N Shiva Prasad, HA Karthik Urala, BN Shiva Prasad   +3 more
core   +1 more source

Identification of C3d Complement Fragments in Lesional Tissues in ANCA‐Associated Vasculitis

ACR Open Rheumatology, Volume 8, Issue 11, November 2026.
Objective Antineutrophil cytoplasmic antibody–associated vasculitis (AAV) is typically described as “pauci‐immune” due to the absence or weak detection of Igs and complement activation within AAV tissue lesions. However, complement fragments have been recently reported in significant amounts in damaged tissue in AAV, notably in traps formed by ...
Claire Galand, Fei Liu, Katherine A. Vernon, Ravi Vats, Christine Lian, V. Michael Holers, Michael Woodbury, H. Terence Cook, David Cuthbertson, Nader Khalidi, Curry Koening, Carol A. Langford, Carol A. McAlear, Paul A. Monach, Christian Pagnoux, Jason A. Campagna, Stefan Wawersik, Shelia Violette, Peter A. Merkel, for the Vasculitis Clinical Research Consortium   +19 more
wiley   +1 more source

Combined pulmonary fibrosis and emphysema with myeloperoxidase-antineutrophil cytoplasmic antibody positivity that resolved upon smoking cessation

Respiratory Medicine Case Reports, 2018
Myeloperoxidase antineutrophil cytoplasmic autoantibody (MPO-ANCA) is well-known as a serological marker for small-vessel vasculitis. However, when a smoker with interstitial lung disease (ILD) exhibits serum ANCA positivity without systemic vasculitis ...
Masahiro Nemoto, Satoshi Noma, Ayumu Otsuki, Kei Nakashima, Koichi Honma, Takeshi Johkoh, Junya Fukuoka, Masahiro Aoshima   +7 more
doaj   +1 more source

Seronegative Propylthiouracil‐Induced Reversible Bilateral Sensory Neural Hearing Loss Without Systemic Vasculitis: A Case Report and Review of Literature

Clinical Case Reports, Volume 14, Issue 11, November 2026.
ABSTRACT Propylthiouracil (PTU) is a thioamide drug used in the management of hyperthyroidism in selected clinical settings. While PTU is associated with well‐known adverse effects such as hepatotoxicity, agranulocytosis, and antineutrophil cytoplasmic antibody (ANCA)‐associated vasculitis, ototoxicity is an exceptionally rare complication.
Adane Alemayehu Abera, Genetu Dagnaw Alemayehu, Zelalem Tadesse Wondimu, Behaylu Tesfamaryam Hagos, Mequannet Tesfaw Addis, Mohammedsefa Arusi Dari   +5 more
wiley   +1 more source

Antineutrophil Cytoplasmic Antibody-associated Vasculitis Complicating Graves' Disease: Report of Two Adult Cases [PDF]

, 2000
Two adult female patients with established Graves' disease were treated with propylthiouracil (PTU). One patient developed agranulocytosis, high fever of unknown origin and bilateral episcleritis.
Eguchi, Katsumi, Usa, Toshirou, Ejima, Eri, Ide, Akane, Kawakami, Atsushi, Yokoyama, Naokata, Sera, Nobuko, Tominaga, Tan, Abe, Yasuyo, Ashizawa, Kiyoto   +9 more
core  

Rapidly Progressing Interstitial Fibrosis and Glomerulonephritis due to Granulomatosis With Polyangiitis Presenting With Calf Pain

Clinical Case Reports, Volume 14, Issue 11, November 2026.
ABSTRACT We describe a 51‐year‐old male presenting with bilateral calf pain and found to have rapidly progressing pulmonary‐renal syndrome due to GPA vasculitis, despite completing an empiric course of steroids for a gout flare. This case underscores the heterogeneous nature of GPA and the importance of early strong immunosuppressive therapy.
Lily Gupta (Allison), Yingxue Wang, Eugenia Chen   +2 more
wiley   +1 more source

Renal Transplantation in Antineutrophil Cytoplasmic Antibody-Associated Vasculitis: A Multicenter Experience [PDF]

, 2011
Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is a common cause of rapidly progressive glomerulonephritis resulting in end-stage renal disease (ESRD). The optimal timing of kidney transplantation (KTX) for ESRD as a result of AAV
Alfonso Eirin, Valentina Irazabal, Maria, Fernando C. Fervenza, Fervenza, Fernando C., Seo, Philip, True, Karin, Karin True, Specks, Ulrich, Nachman, Patrick, Ulrich Specks, Geetha, Duvuru, Eirin, Alfonso, Duvuru Geetha, Maria Valentina Irazabal, Philip Seo, Patrick Nachman   +15 more
core   +1 more source

Pulmonary tularemia with antineutrophil-cytoplasmic-antibody-negative pauci-immune crescentic glomerulonephritis causing acute kidney injury: a case report and review of the literature

Journal of Medical Case Reports
Background Tularemia is a zoonotic disease that is rarely diagnosed in Europe. Its clinical presentation is highly variable, requiring consideration of a broad differential diagnosis.
Matthias Feyrer, Michael Städt, Pawlos Ichtiaris, Philipp Koehl, Alexander Schuh   +4 more
doaj   +1 more source

Antineutrophil cytoplasmic antibody-positive scleritis: Clinical profile of patients from a tuberculosis-endemic region

Indian Journal of Ophthalmology, 2018
Purpose: To report the clinical profile of a series of antineutrophil cytoplasmic antibody (ANCA)-associated scleritis in Indian population. Methods: We conducted a retrospective review of medical records of 33 eyes of 26 consecutive patients with ...
Parthopratim Dutta Majumder, Sridharan Sudharshan, Amala Elizabeth George, Sudha K Ganesh, Jyotirmay Biswas   +4 more
doaj   +1 more source

Neutrophils: Heterogeneity, Biology, Diseases, and Therapeutic Strategies

MedComm, Volume 7, Issue 11, November 2026.
Neutrophils exhibit remarkable functional plasticity and play dual roles in tissue protection and disease progression. This review summarizes their key biological functions and highlights the shift from conventional broad‐spectrum interventions to neutrophil‐based drug delivery systems.
Yibing Zhang, Siwen Wu, Yusi Wang, Die Hu, Li Yang   +4 more
wiley   +1 more source