ABSTRACT Tocilizumab is an interleukin‐6 (IL‐6) receptor antagonist indicated for various rheumatologic conditions. While hepatotoxicity is a recognized adverse effect, it predominantly manifests as hepatocellular injury. We report a rare case of drug‐induced liver injury (DILI) presenting with a cholestatic pattern and cholangitis features in a 75 ...
Louis‐Edmond Barbaro +7 more
wiley +1 more source
Diagnostic Utility of Antibodies to Extractable Nuclear Antigens in the Absence of Positive Antinuclear Antibodies. [PDF]
Huang J, Dargham BB, Luggen M.
europepmc +1 more source
Pulmonary Arterial Hypertension Associated With Chronic Mephedrone Use: A Case Report
ABSTRACT Mephedrone is a synthetic cathinone with sympathomimetic effects, but has not previously been linked to pulmonary arterial hypertension (PAH). We report a 42‐year‐old woman with no prior cardiopulmonary disease who presented with severe pre‐capillary PAH after a decade of near‐daily mephedrone use.
Masoud Kashoub +8 more
wiley +1 more source
Binding of established antinuclear antibodies to neurons depends on tissue fixation and underlying autoantigens. [PDF]
Li LY +6 more
europepmc +1 more source
We report a case of severe pulmonary vein stenosis presenting with pulmonary consolidation and massive pleural effusion, successfully diagnosed using three‐dimensional computed tomography. ABSTRACT We report a rare case of pulmonary vein stenosis (PVS) presenting with massive pleural effusion 5 months after radiofrequency catheter ablation (RFCA) for ...
Yasuhiko Nikaido +6 more
wiley +1 more source
More Than Just Antinuclear Antibodies: IgG Sialylation May Tip the Balance in Autoimmunity. [PDF]
Martins Centeio R, Wang TT.
europepmc +1 more source
Erlotinib‐Induced Pneumatosis Intestinalis: A Case Report and Review of Literature
We report a rare case of erlotinib‐induced pneumatosis intestinalis that worsened during continued treatment and rapidly improved after erlotinib discontinuation. This case highlights the importance of recognizing pneumatosis intestinalis as a potential adverse event of EGFR‐TKIs. ABSTRACT Pneumatosis intestinalis (PI) is a rare condition characterized
Shunsuke Saito +6 more
wiley +1 more source
Antinuclear antibodies seroconversion and endoscopic response to infliximab in biologic-naive Crohn's disease: a Chinese single-center, retrospective study. [PDF]
Tong J +10 more
europepmc +1 more source
A 74‐year‐old woman was treated for 7 years as culture‐negative bronchiectasis before palpable purpura, haemoptysis, and acute kidney injury revealed MPO‐ANCA vasculitis with pauci‐immune crescentic glomerulonephritis. Rituximab‐based induction produced near‐complete resolution of the pulmonary consolidations and sustained clinical remission at 15 ...
Andrew Kim +5 more
wiley +1 more source
CytoBead ANA 2 assay - a novel method for the detection of antinuclear antibodies. [PDF]
Roei T +15 more
europepmc +1 more source

