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Chapter 14a. Human Antiparasitic Agents
1966Publisher Summary This chapter discusses human antiparasitic agents with frequent reference to recent reviews that provide background information on broad aspects of parasite chemotherapy. Recently, significant progress has been made against parasitic diseases.
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Chapter 14. Antiparasitic Agents
1972Publisher Summary This chapter describes the development and clinical studies of antiparasitic agents. The natural or acquired immunity to pathologic parasite infections is abolished by immunosuppression, particularly by betamethasone, a corticoid. Identical dihydrofolate reductase enzymes, isolated from P. berghei and P.
M. Hoffer, A.I. Rachlin
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Chapter 15. Antiparasitic Agents
1977Publisher Summary The synthesis of new quinoline methanols, phenanthrene methanols, and naphthalene methanols aims at finding compounds of high activity and low phototoxicity. The transfer of drug resistance do not take place between different species but occurs between different variants of the same species 96 hours after inoculation or later ...
C WANG, M FISHER
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Chapter 13: Antiparasitic Agents
1976Publisher Summary This chapter emphasizes the need for screening all drugs for mutagenic potential. A new fluorometric method has been used to determine amodiaquin in serum, plasma, and red cells. The use of drug mixtures in rodent malaria may prevent formation of drug resistance against one of the components but not against the others.
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Chapter 15. Antiparasitic Agents
1984Publisher Summary This chapter discusses the philosophy of a pharmaceutical company towards involvement with tropical diseases. The discussion includes a review on the new experimental anti-malarial drugs and a volume on “new trends in malaria chemotherapy;” major forthcoming therapeutic advances for leishmaniasis disease entity; human and animal ...
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Chapter 14. Antiparasitic Agents
1982Publisher Summary This chapter discusses the pharmacokinetics, metabolism, and adverse reactions of 5-nitroimidazoles together with detailed reviews of their mode of action on protozoa and bacteria. The protozoa and bacteria discussed in the chapter are trichomonas, amoebae, coccidia, African trypanosomes, trypanosoma cruzi, leishmania, and malarial ...
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