Results 181 to 190 of about 1,521,556 (235)
Evaluation of the in vitro activity of synthetic derivatives of N-cyclohexyl-3-(3-methylphenyl)-1,2,4-oxadiazole-5-amine on the strain y of Trypanosoma cruzi and an in vivo toxicity study. [PDF]
Mem Inst Oswaldo CruzRocha YM +13 more
europepmc +1 more source
mNGS-Assisted Diagnosis of Visceral Leishmaniasis Presenting as Hemophagocytic Lymphohistiocytosis: Two Cases Confirmed by rK39. [PDF]
Infect Drug ResistChang C +4 more
europepmc +1 more source
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IDrugs : the investigational drugs journal, 2011
Parasitic diseases predominantly affect the developing world because of poor sanitation, poor living conditions, and lack of medical care. The relative insulation of the developed countries has been protective until recently, when several factors have made populations worldwide potentially at risk of infection by any transmissible agent.
Peter Weller, Karin Leder
exaly +2 more sources
Parasitic diseases predominantly affect the developing world because of poor sanitation, poor living conditions, and lack of medical care. The relative insulation of the developed countries has been protective until recently, when several factors have made populations worldwide potentially at risk of infection by any transmissible agent.
Peter Weller, Karin Leder
exaly +2 more sources
Mayo Clinic Proceedings, 1992
Several important developments have occurred in recent years in the chemotherapy for and prophylaxis of parasitic infections. Although mefloquine is clearly the most effective agent for prevention of chloroquine-resistant falciparum malaria, its use has been compromised by side effects, both real and imagined. Well-designed studies have shown that side
Kazuhiko Otoguro, Haruo Tanaka
+7 more sources
Several important developments have occurred in recent years in the chemotherapy for and prophylaxis of parasitic infections. Although mefloquine is clearly the most effective agent for prevention of chloroquine-resistant falciparum malaria, its use has been compromised by side effects, both real and imagined. Well-designed studies have shown that side
Kazuhiko Otoguro, Haruo Tanaka
+7 more sources
Conjugates Containing Two and Three Trithiolato-Bridged Dinuclear Ruthenium(II)-Arene Units as In Vitro Antiparasitic and Anticancer Agents [PDF]
Pharmaceuticals, 2020 The synthesis, characterization, and in vitro antiparasitic and anticancer activity evaluation of new conjugates containing two and three dinuclear trithiolato-bridged ruthenium(II)-arene units are presented.
Martin Hungerbuehler +2 more
exaly +3 more sources
Aromatic diamidines as antiparasitic agents
Expert Opinion on Investigational Drugs, 2005Parasitic infections are widespread in developing countries and frequently associated with immunocompromised patients in developed countries. Consequently, such infections are responsible for a significant amount of human mortality, morbidity and economic hardship.
M N C, Soeiro +3 more
openaire +2 more sources
Chemotherapy, 2009
Some acridine compounds referred to as 9-imino, 9-oxo and 9-thio derivatives were screened for activity against Trypanosoma cruzi in vitro. The results are discussed here with reference to the structure of the compounds tested. Attempts to elucidate the mode of action of active acridines are also included.
Antonio Osuna +10 more
openaire +1 more source
Some acridine compounds referred to as 9-imino, 9-oxo and 9-thio derivatives were screened for activity against Trypanosoma cruzi in vitro. The results are discussed here with reference to the structure of the compounds tested. Attempts to elucidate the mode of action of active acridines are also included.
Antonio Osuna +10 more
openaire +1 more source