In vitro and in vivo acaricidal properties of orally delivered ivermectin against the blacklegged tick, Ixodes scapularis [PDF]
Parasites & VectorsBackground The lack of effective and affordable new environmental tick control products is one of the major challenges to the existing control strategies against the blacklegged tick (Ixodes scapularis), the vector of Lyme disease affecting public health
Jolieke G. van Oosterwijk +3 more
doaj +2 more sources
A five-day course of ivermectin for the treatment of COVID-19 may reduce the duration of illness
International Journal of Infectious Diseases, 2021 Ivermectin, a US Food and Drug Administration-approved anti-parasitic agent, was found to inhibit severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) replication in vitro.
Jyoti Somani +2 more
exaly +3 more sources
Efficacy of ivermectin for malaria vector control: a systematic review and meta-analysis of randomized clinical trials [PDF]
Malaria JournalBackground Despite global malaria control efforts, malaria continues to cause approximately 241–249 million cases and over 600,000 deaths annually. Ivermectin, a broad-spectrum antiparasitic drug with endectocidal activity against mosquitoes feeding on ...
Shrouk Ramadan +11 more
doaj +2 more sources
Acute toxicity events of ivermectin in chicks’ model [PDF]
Iraqi Journal of Veterinary Sciences, 2022 Ivermectin is a very safe drug; however, there are many studies on its toxic effects in different animals due to sensitivity, misuse, or accidental overdose.
Tamara K. Al-Najmawi, Muna H. Al-Zubaidy
doaj +1 more source
In vitro larvicidal activity of ivermectin and povidone-iodine against Oestrus ovis.
PLoS ONE, 2021 PurposeTo assess the in vitro larvicidal activity of ivermectin and povidone-iodine (PVP-I) against Oestrus ovis, the most frequent cause of external ophthalmomyiasis.MethodsL1 O.
Giuseppe D'Amico Ricci +6 more
doaj +2 more sources
Ivermectin metabolites reduce Anopheles survival
Scientific Reports, 2023 Ivermectin mass drug administration to humans or livestock is a potential vector control tool for malaria elimination. The mosquito-lethal effect of ivermectin in clinical trials exceeds that predicted from in vitro laboratory experiments, suggesting ...
Kevin C. Kobylinski +14 more
doaj +1 more source
Current therapeutic applications and pharmacokinetic modulations of ivermectin [PDF]
Veterinary World, 2019 Ivermectin is considered to be a wonder drug due to its broad-spectrum antiparasitic activity against both ectoparasites and endoparasites (under class of endectocide) and has multiple applications in both veterinary and human medicine.
Khan Sharun +5 more
doaj +1 more source
Pharmacokinetics of ivermectin metabolites and their activity against Anopheles stephensi mosquitoes
Malaria Journal, 2023 Background Ivermectin (22,23-dihydroavermectin B1a: H2B1a) is an endectocide used to treat worm infections and ectoparasites including lice and scabies mites.
Charlotte Kern +5 more
doaj +1 more source
Integrated analysis reveals FOXA1 and Ku70/Ku80 as targets of ivermectin in prostate cancer
Cell Death and Disease, 2022 Ivermectin is a widely used antiparasitic drug and shows promising anticancer activity in various cancer types. Although multiple signaling pathways modulated by ivermectin have been identified in tumor cells, few studies have focused on the exact target
Shidong Lv +7 more
doaj +1 more source
Parasites & Vectors, 2021 Background Despite remarkable success obtained with current malaria vector control strategies in the last 15 years, additional innovative measures will be needed to achieve the ambitious goals for malaria control set for 2030 by the World Health ...
Patricia Nicolas +7 more
doaj +1 more source