Pharmacokinetics, safety, and efficacy of a single co-administered dose of diethylcarbamazine, albendazole and ivermectin in adults with and without Wuchereria bancrofti infection in Cote d\u27Ivoire [PDF]
, 2019 BackgroundA single co-administered dose of ivermectin (IVM) plus diethylcarbamazine (DEC) plus albendazole (ALB), or triple-drug therapy, was recently found to be more effective for clearing microfilariae (Mf) than standard DEC plus ALB currently used ...
Bjerum, Catherine M +9 more
core +4 more sources
Would ivermectin for malaria control be beneficial in onchocerciasis-endemic regions?
Infectious Diseases of Poverty, 2019 Background There is accumulating evidence supporting the use of ivermectin as a malaria control tool. Recent findings from the repeat ivermectin mass drug administrations for control of malaria trial demonstrated a reduced incidence of malaria in ...
Joseph Nelson Siewe Fodjo +5 more
doaj +1 more source
South African Medical Journal, 2022 Background. Ivermectin is an antiparasitic drug that has shown in vitro activity against COVID‑19. Clinical studies supporting ivermectin for COVID‑19 prevention and treatment are conflicting, with important limitations. Public support for ivermectin is
V Pillay-Fuentes Lorente +8 more
doaj +1 more source
Scabies: Application of the Novel Identify-Isolate-Inform Tool for Detection and Management [PDF]
, 2020 Scabies is a highly contagious, globally prevalent, parasitic skin infestation caused by Sarcoptes scabiei var. hominis, also known as the itch mite.
Al-Wabel, Abdussalam +7 more
core
Increased expression of a microRNA correlates with anthelmintic resistance in parasitic nematodes [PDF]
, 2017 Resistance to anthelmintic drugs is a major problem in the global fight against parasitic nematodes infecting humans and animals. While previous studies have identified mutations in drug target genes in resistant parasites, changes in the expression ...
Bartley, David +13 more
core +2 more sources
Comparative effect of dose escalation of nanocapsulated ivermectin against mange in rabbits
German Journal of Veterinary Research, 2022 The present study aimed to investigate the effects of nano-capsulated ivermectin on the liver and kidney function and oxidative status in mite infested-rabbits, compared to ivermectin. Additionally, the ivermectin residue profile in adipose tissue, liver,
Azza Abdelmoteleb +3 more
doaj +1 more source
A stochastic model to investigate the effects of control strategies on calves exposed to Ostertagia ostertagi [PDF]
, 2016 Predicting the effectiveness of parasite control strategies requires accounting for the responses of individual hosts and the epidemiology of parasite supra- and infra-populations.
Berk, Zoe +3 more
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Molecular mechanisms of Cys-loop ion channel receptor modulation by ivermectin
Frontiers in Molecular Neuroscience, 2012 Ivermectin is a gold standard anthelmintic drug that works by potently depressing neuronal activity and muscular contractility in arthropods and nematodes. At the molecular level, ivermectin activates inhibitory glutamate-gated chloride channels (GluClRs)
Timothy eLynagh, Joe eLynch
doaj +1 more source
Comparison between the efficacy of ivermectin and other drugs in treatment of cutaneous leishmaniasis [PDF]
Iraqi Journal of Veterinary Sciences, 2009 The study was conducted to compare the efficacy of ivermectin with some drugs in treatment of cutaneous leishmaniasis in vitro and in Balb/ C mice. The cultivation of Leishmania tropica was done on Nove MacNeal-Nicole medium (NNN).
M. A. Kadir, H. S. Aswad, A. M. Al-Samarai and G. A. Al-Mula
doaj +1 more source
Anthelmintic tolerance in free-living and facultative parasitic isolates of Halicephalobus (Panagrolaimidae) [PDF]
, 2012 Studies on anthelmintic resistance in equine parasites do not include facultative parasites. Halicephalobus gingivalis is a free-living bacteriovorous nematode and a known facultative parasite of horses with a strong indication of some form of tolerance ...
Andrássy +18 more
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