Importance Ivermectin, an inexpensive and widely available antiparasitic drug, is prescribed to treat COVID-19. Evidence-based data to recommend either for or against the use of ivermectin are needed.
Steven Chee-Loon Lim +25 more
semanticscholar +1 more source
The geographic distribution of loa loa in Africa : results of large-scale implementation of the Rapid Assessment Procedure for Loiasis (RAPLOA) [PDF]
Background: Loiasis is a major obstacle to ivermectin treatment for onchocerciasis control and lymphatic filariasis elimination in central Africa. In communities with a high level of loiasis endemicity, there is a significant risk of severe adverse ...
Noma, Mounkaila +6 more
core +5 more sources
Integrated analysis reveals FOXA1 and Ku70/Ku80 as targets of ivermectin in prostate cancer
Ivermectin is a widely used antiparasitic drug and shows promising anticancer activity in various cancer types. Although multiple signaling pathways modulated by ivermectin have been identified in tumor cells, few studies have focused on the exact target
Shidong Lv +7 more
doaj +1 more source
Validation of the rapid assessment procedure for loiasis (RAPLOA) in the democratic republic of CongoS [PDF]
Background: A simple method called RAPLOA, to rapidly assess what proportion of people in a community are infected with L. loa and hence which communities are at high risk of severe adverse reactions following ivermectin treatment, was developed in ...
Tepage, Floribert +6 more
core +5 more sources
Rates of microfilarial production by Onchocerca volvulus are not cumulatively reduced by multiple ivermectin treatments. [PDF]
Regular distribution of ivermectin reduces onchocerciasis transmission and morbidity by killing, within humans, the microfilarial stage of the parasite (microfilaricidal effect).
Bottomley, Christian +3 more
core +1 more source
Control, elimination, and eradication of river blindness: scenarios, timelines, and ivermectin treatment needs in Africa [PDF]
River blindness (onchocerciasis) causes severe itching, skin lesions, and vision impairment including blindness. More than 99% of all current cases are found in sub-Saharan Africa.
Remme, JHF +31 more
core +3 more sources
Waspada Panic Buying Ivermectin di Apotek [PDF]
SENIN pagi yang lalu, saya terlibat diskusi menarik dengan beberapa tetangga perihal penggunaan obat cacingan, Ivermectin, yang sedang populer saat ini.
Andi Hermansyah, -
core +1 more source
Impact of Long-Term Treatment with Ivermectin on the Prevalence and Intensity of Soil-Transmitted Helminth Infections [PDF]
Background Control of soil-transmitted helminth (STH) infections relies on the periodic and long-term administration of anthelmintic drugs to high-risk groups, particularly school-age children living in endemic areas.
Oviedo, G +25 more
core +1 more source
Introgression of ivermectin resistance genes into a susceptible Haemonchus contortus strain by multiple backcrossing [PDF]
Anthelmintic drug resistance in livestock parasites is already widespread and in recent years there has been an increasing level of anthelmintic drug selection pressure applied to parasitic nematode populations in humans leading to concerns regarding the
Elizabeth Redman (183534) +34 more
core +1 more source
Repeated high doses of avermectins cause prolonged sterilisation, but do not kill, Onchocerca ochengi adult worms in African cattle [PDF]
Ivermectin (Mectizan, Merck and CO. Inc.) is being widely used in the control of human onchocerciasis (Onchoverca volvulus) because of its potent effect on microfilariae.
Barend M deC Bronsvoort +15 more
core +1 more source

