Results 51 to 60 of about 48,951 (258)

Plasma pharmacokinetic profile of fluralaner (Bravecto™) and ivermectin following concurrent administration to dogs

Parasites & Vectors, 2015
Background Fluralaner is a novel systemic ectoparasiticide for dogs providing immediate and persistent flea, tick and mite control after a single oral dose.
Feli M. Walther, Mark J. Allan, Rainer KA Roepke   +2 more
doaj   +1 more source

Identification of the metabolites of ivermectin in humans

Pharmacology Research & Perspectives, 2021
Mass drug administration of ivermectin has been proposed as a possible malaria elimination tool. Ivermectin exhibits a mosquito‐lethal effect well beyond its biological half‐life, suggesting the presence of active slowly eliminated metabolites.
Phornpimon Tipthara, Kevin C. Kobylinski, Markus Godejohann, Borimas Hanboonkunupakarn, Alison Roth, John H. Adams, Nicholas J. White, Podjanee Jittamala, Nicholas P. J. Day, Joel Tarning   +9 more
doaj   +1 more source

Ivermectin Treatment and Sanitation Effectively Reduce Strongyloides stercoralis Infection Risk in Rural Communities in Cambodia [PDF]

, 2016
BACKGROUND: Strongyloides stercoralis is the only soil-transmitted helminth with the ability to replicate within its host, leading to long-lasting and potentially fatal infections. It is ubiquitous and its worldwide prevalence has recently been estimated
Virak Khieu (236174), Christian Schindler (71594), Virak Khieu, Schär, Fabian, Fabian Schär (280371), Hanspeter Marti, Sinuon Muth, Sinuon Muth (251084), Char, Meng Chuor, Odermatt, Peter, Muth, Sinuon, Khieu, Virak, Forrer, Armelle, Christian Schindler, Fabian Schär, Peter Odermatt, Marti, Hanspeter, Peter Odermatt (148926), Schindler, Christian, Meng Chuor Char, Hanspeter Marti (224864), Meng Chuor Char (3070287), Armelle Forrer (183487), Armelle Forrer   +23 more
core   +1 more source

The mechanisms of action of ivermectin against SARS-CoV-2—an extensive review

Journal of antibiotics (Tokyo. 1968), 2021
Considering the urgency of the ongoing COVID-19 pandemic, detection of new mutant strains and potential re-emergence of novel coronaviruses, repurposing of drugs such as ivermectin could be worthy of attention.
A. Zaidi, P. Dehgani-Mobaraki
semanticscholar   +1 more source

Effects of the veterinary pharmaceutical ivermectin in indoor aquatic microcosms [PDF]

, 2010
The effects of the parasiticide ivermectin were assessed in plankton-dominated indoor microcosms. Ivermectin was applied once at concentrations of 30, 100, 300, 1000, 3000, and 10,000 ng/l.
Reichman, E.P., Harry Boonstra, Erik P. Reichman, Boonstra, H., van den Brink, P.J., Brink, P.J., van den, Paul J. van den Brink   +6 more
core   +1 more source

Clinical study evaluating the efficacy of ivermectin in COVID‐19 treatment: A randomized controlled study

Journal of Medical Virology, 2021
Researchers around the world are working at record speed to find the best ways to treat and prevent coronavirus disease 2019 (COVID‐19). This study aimed to evaluate the efficacy of ivermectin for the treatment of hospitalized mild to moderate COVID‐19 ...
S. Abdel-salam, R. Noor, R. Badawi, M. Khalaf, E. Esmail, S. Soliman, M. S. Abd El Ghafar, M. Elbahnasawy, E. Moustafa, S. Hassany, M. Medhat, H. Ramadan, M. Eldeen, Mohamed Alboraie, A. Cordie, G. Esmat   +15 more
semanticscholar   +1 more source

Ivermectin susceptibility, sporontocidal effect, and inhibition of time to re-feed in the Amazonian malaria vector Anopheles darlingi

Malaria Journal, 2017
Background Outdoor malaria transmission hinders malaria elimination efforts in the Amazon region and novel vector control tools are needed. Ivermectin mass drug administration (MDA) to humans kills wild Anopheles, targets outdoor-feeding vectors, and can
Kevin C. Kobylinski, Karín S. Escobedo-Vargas, Victor M. López-Sifuentes, Salomón Durand, Edward S. Smith, G. Christian Baldeviano, Robert V. Gerbasi, Sara-Blythe Ballard, Craig A. Stoops, Gissella M. Vásquez   +9 more
doaj   +1 more source

Use of Ivermectin as a Potential Chemoprophylaxis for COVID-19 in Egypt: A Randomised Clinical Trial [PDF]

Journal of Clinical and Diagnostic Research, 2021
Introduction: The rate of secondary attacks of SARS-COV-2 is high among household close contacts. Social distancing, isolation and infection control measures are important for preventing exposure to infection, but insufficient.
Waheed M Shoumann, Abdelmonem Awad Hegazy, Ramadan M Nafae, Moustafa I Ragab, Saad R Samra, Dalia Anas Ibrahim, Tarek H AL-Mahrouky, Ashraf E Sileem   +7 more
doaj   +1 more source

Ivermectin: An Anthelmintic, an Insecticide, and Much More

Trends in Parasitology, 2020
Here we tell the story of ivermectin, describing its anthelmintic and insecticidal actions and recent studies that have sought to reposition ivermectin for the treatment of other infectious diseases.
Richard J. Martin, A. Robertson, Shivani Choudhary   +2 more
semanticscholar   +1 more source

Exploring the binding efficacy of ivermectin against the key proteins of SARS-CoV-2 pathogenesis: an in silico approach

Future Virology, 2021
Aim: COVID-19 is currently the biggest threat to mankind. Recently, ivermectin (a US FDA-approved antiparasitic drug) has been explored as an anti-SARS-CoV-2 agent.
Abhigyan Choudhury, N. Das, Ritwik Patra, M. Bhattacharya, Pratik Ghosh, B. C. Patra, S. Mukherjee   +6 more
semanticscholar   +1 more source