Ivermectin Does Not Protect against SARS-CoV-2 Infection in the Syrian Hamster Model
Microorganisms, 2022 Ivermectin, an FDA-approved antiparasitic drug, has been reported to have in vitro activity against SARS-CoV-2. Increased off-label use of ivermectin for COVID-19 has been reported.
Caroline S. Foo +6 more
doaj +1 more source
Ivermectin and Novel Coronavirus Disease (COVID-19): Keeping Rigor in Times of Urgency
American Journal of Tropical Medicine and Hygiene, 2020 Ivermectin and Novel Coronavirus Disease (COVID-19): Keeping Rigor in Times of ...
Carlos J. Chaccour +3 more
semanticscholar +1 more source
The actions of chloride channel blockers, barbiturates and a benzodiazepine on Caenorhabditis elegans glutamate- and ivermectin-gated chloride channel subunits expressed in Xenopus oocytes [PDF]
, 2009 The pharmacology of Caenorhabditis elegans glutamate-gated chloride (GluCl) channels was determined by making intracellular voltage-clamp recordings from Xenopus oocytes expressing GluCl subunits. As previously reported (Cully et al.
Bush, Elizabeth +3 more
core +1 more source
Ivermectin Docks to the SARS-CoV-2 Spike Receptor-binding Domain Attached to ACE2
In Vivo, 2020 Background/Aim: Coronavirus disease 2019 (COVID-19) is an infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). One drug that has attracted interest is the antiparasitic compound ivermectin, a macrocyclic lactone ...
S. Lehrer, P. Rheinstein
semanticscholar +1 more source
Long-term periodic anthelmintic treatments are associated with increased allergen skin reactivity. [PDF]
, 2010 BACKGROUND: The low prevalence of allergic disease in the rural tropics has been attributed to the protective effects of chronic helminth infections. There is concern that treatment-based control programmes for these parasites may lead to an increase in ...
Oviedo, G +24 more
core +1 more source
Fate and Effects of Parasiticides in the Pasture Environment [PDF]
, 2009 Parasiticides are used in the treatment of livestock animals. Following use, they may be excreted to the environment where they can impact non-target organisms. European regulations require an environmental risk assessment (ERA) for parasiticides before
Pope, Louise Jay
core +6 more sources
Ivermectin: A Multifaceted Drug With a Potential Beyond Anti-parasitic Therapy
CureusIvermectin was first discovered in the 1970s by Japanese microbiologist Satoshi Omura and Irish parasitologist William C. Campbell. Ivermectin has become a versatile pharmaceutical over the past 50 years.
Baneet Kaur, C. Blavo, Mayur Parmar
semanticscholar +1 more source
Selamectin is the avermectin with the best potential for Buruli ulcer treatment [PDF]
, 2015 A comprehensive analysis was done to evaluate the potential use of anti-parasitic macrocyclic lactones (including avermectins and milbemycins) for Buruli ulcer (BU) therapy.
Gerd Pluschke +7 more
core +2 more sources
Would ivermectin for malaria control be beneficial in onchocerciasis-endemic regions?
Infectious Diseases of Poverty, 2019 Background There is accumulating evidence supporting the use of ivermectin as a malaria control tool. Recent findings from the repeat ivermectin mass drug administrations for control of malaria trial demonstrated a reduced incidence of malaria in ...
Joseph Nelson Siewe Fodjo +5 more
doaj +1 more source
Pediatric Use of Off-Label Medicines and Nonevidence-Based Supplements for COVID-19: Findings From the 2015 Pelotas Birth Cohort Study (Brazil). [PDF]
Pharmacoepidemiol Drug SafABSTRACT Purpose Pediatric off‐label medicine use increased during the COVID‐19 pandemic, exposing children to nonevidence‐based treatments. We described the use of nonevidence‐based COVID‐19 medicines and supplements among children from the 2015 Pelotas Birth Cohort, according to sociodemographic and health‐related characteristics.
Bertoldi AD +5 more
europepmc +2 more sources