Results 61 to 70 of about 29,185 (219)

Parascaris spp. induced surgical colic in juvenile horses—A Scandinavian perspective

Equine Veterinary Journal, EarlyView.
Abstract Background Parascaris spp. commonly infects foals, and high burdens can cause fatal small intestinal impactions. Progressive anthelmintic resistance poses a risk for an increase of Parascaris spp. related disease in juvenile horses. Objectives To investigate Parascaris‐related surgical intestinal lesions, with special emphasis on ascarid ...
E. Tydén, I. R. Hellings, K. Toft Nielsen, A. Bergren, I. Holmgren, S. Attin, T. Pihl, A. Kendall, Y. Hedberg Alm   +8 more
wiley   +1 more source

Lymphatic Filariasis Control in Tanzania: Effect of Six Rounds of Mass Drug Administration with Ivermectin and Albendazole on Infection and Transmission. [PDF]

, 2013
Control of lymphatic filariasis (LF) in most countries of sub-Saharan Africa is based on annual mass drug administration (MDA) with a combination of ivermectin and albendazole, in order to interrupt transmission. We present findings from a detailed study
Simonsen, Paul E, Mwele N Malecela, Derua, Yahya A, William N Kisinza, Paul E Simonsen, Pedersen, Erling M, Kisinza, William N, Yahya A Derua, Malecela, Mwele N., Derua, Yahya A., Kisinza, William N., Malecela, Mwele N, Magesa, Stephen M., Pedersen, Erling Møller, Stephen M Magesa, Erling M Pedersen, Magesa, Stephen M, Simonsen, Paul Erik   +17 more
core   +1 more source

A compendium of extracellular vesicle biogenesis inhibitors: From bench to bedside

Interdisciplinary Medicine, EarlyView.
This review explores a decade of research on extracellular vesicles (EVs), detailing their biogenesis and roles in health and disease. It emphasizes EVs' relevance for potential medical applications covering various conditions such as cancer, neurodegeneration, inflammation, and infectious diseases, bridging experimental findings with clinical ...
Stefano Vecchione, Ana Talamillo, Juan M. Falcón‐Pérez   +2 more
wiley   +1 more source

Validation of the rapid assessment procedure for loiasis (RAPLOA) in the democratic republic of CongoS [PDF]

, 2012
Background: A simple method called RAPLOA, to rapidly assess what proportion of people in a community are infected with L. loa and hence which communities are at high risk of severe adverse reactions following ivermectin treatment, was developed in ...
Wanji Samuel, Tepage Floribert, Maurice N Mutro, Floribert Tepage, Mutro, Maurice N., Ukety, Tony O., Wanji, Samuel, Ukety Tony O, Remme, Jan H., Akotshi Dowo O, Tony O Ukety, Diggle Peter J, Dowo O Akotshi, Tepage, Floribert, Akotshi, Dowo O., Peter J Diggle, Samuel Wanji, Jan H Remme, Mutro Maurice N, Diggle, Peter J., Remme Jan H   +20 more
core   +1 more source

Corticosterone Under Experimental Manipulation of Nutrition and Parasite Burden in a Wild Rodent System

Journal of Experimental Zoology Part A: Ecological and Integrative Physiology, EarlyView.
ABSTRACT Environmental pressures shape survival and life‐history dynamics partly by triggering the release of glucocorticoids, whose short‐term benefits but long‐term costs make it essential to understand what drives their levels. Here, we used an experimental manipulation of two environmental stressors—food availability and parasite burden—to directly
Sarah E. Wolf, Olga Dłużniewska, Simon A. Babayan, Amy B. Pedersen, Tom J. Little   +4 more
wiley   +1 more source

Actions of Agonists, Fipronil and Ivermectin on the Predominant In Vivo Splice and Edit Variant (RDLbd, I/V) of the Drosophila GABA Receptor Expressed in Xenopus laevis Oocytes

, 2014
Ionotropic GABA receptors are the targets for several classes of insecticides. One of the most widely-studied insect GABA receptors is RDL (resistance to dieldrin), originally isolated from Drosophila melanogaster.
Philip Biggin, Suwanmanee, S, Musgaard, M, David Sattelle, Steven David Buckingham, Lees, K, Sattelle, D, Maria Musgaard, Siros Suwanmanee, Kristin Lees, Buckingham, SD, Biggin, P   +11 more
core   +1 more source

Assay strategies for the discovery and validation of therapeutics targeting Brugia pahangi Hsp90 [PDF]

, 2010
The chemotherapy of lymphatic filariasis relies upon drugs such as diethylcarbamazine and ivermectin that largely target the microfilarial stages of the parasite, necessitating continued treatment over the long reproductive life span of the adult worm ...
Gillan, V., O'Neill, K., Devaney, E., Chiosis Gabriela, Kerry O'Neill, Taldone, T., Devaney Eileen, Taldone Tony, Patel, P., O'Neill Kerry, Rodina, A., Kirsty Maitland, Chiosis, G., Maitland Kirsty, Anna Rodina, Rodina Anna, Victoria Gillan, Tony Taldone, Pallav Patel, Gillan Victoria, Sun, W., Eileen Devaney, Patel Pallav, Weilin Sun, Gabriela Chiosis, Maitland, K., Sun Weilin   +26 more
core   +1 more source

Evidence-based indications for ivermectin in parasitic diseases: An integrated approach to context and challenges in Peru

Parasite Epidemiology and Control, 2023
Ivermectin has emerged as a therapeutic option for various parasitic diseases, including strongyloidiasis, scabies, lice infestations, gnathostomiasis, and myiasis.
Virgilio E. Failoc-Rojas, Heber Silva-Díaz, Jorge L. Maguiña, Alfonso J. Rodriguez-Morales, Cristian Díaz-Velez, Moises Apolaya-Segura, Mario J. Valladares-Garrido   +6 more
doaj   +1 more source

Advancing pharmacometrics in Africa—Transition from capacity development toward job creation

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 407-419, March 2025.
Abstract Trained pharmacometricians remain scarce in Africa due to limited training opportunities, lack of a pharmaceutical product development ecosystem, and emigration to high‐income countries. The Applied Pharmacometrics Training (APT) fellowship program was established to address these gaps and specifically foster job creation for talent retention.
Goonaseelan (Colin) Pillai, Samer Mouksassi, Innocent G. Asiimwe, Craig R. Rayner, Steven Kern, Phumla Sinxadi, Paolo Denti, Eric Decloedt, Catriona Waitt, Bernhards R. Ogutu, Rik de Greef   +10 more
wiley   +1 more source

Co-infection with Onchocerca volvulus and Loa loa microfilariae in central Cameroon: are these two species interacting? [PDF]

, 2006
Ivermectin treatment may induce severe adverse reactions in some individuals heavily infected with Loa loa. This hampers the implementation of mass ivermectin treatment against onchocerciasis in areas where Onchocerca volvulus and L.
Pion, SDS, Clarke, P, Basáñez, M-G, Boussinesq, M, Gardon, J, Filipe, JAN, Kamgno, J   +6 more
core   +1 more source