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Efforts are being directed toward the elimination of onchocerciasis transmission in endemic areas with community-directed treatment with ivermectin (CDTI) in Africa, which greatly reduces onchocerciasis-associated disease. However, onchocerciasis remains
Robert Colebunders +2 more
exaly +3 more sources
In Africa, onchocerciasis and lymphatic filariasis (LF) are co-endemic in many areas. Current efforts to eliminate both diseases are through ivermectin-based mass drug administration (MDA).
Vitaliano A Cama +2 more
exaly +2 more sources
Epidemiology and Risks Survey of Onchocerca volvulus Infection in Igbo-Eze North Local Government Area, Enugu State, Nigeria [PDF]
Background: An epidemiological survey of Onchocerca volvulus infection and onchocerciasis in Igbo-Eze North Local Government Area, Enugu State, Nigeria, was undertaken to assess its distribution and risks among individuals in the area.
Ifeoma Esther Aniaku +9 more
doaj +2 more sources
Repurposing Oxfendazole for Onchocerciasis: Population Pharmacokinetics of a Tablet Formulation in Healthy African Adults [PDF]
ABSTRACT Global efforts to eliminate onchocerciasis are hampered by the lack of a macrofilaricidal drug capable of killing adult parasites. Oxfendazole, a veterinary anthelminthic, exhibits macrofilaricidal activity and holds promise to shorten treatment durations.
Frauke Assmus +12 more
wiley +2 more sources
Malaria in onchocerciasis-endemic populations: patterns in two districts in the Oti and Volta regions of Ghana [PDF]
Background In Ghana and many other sub-Saharan African countries, onchocerciasis and malaria are common infectious diseases that affect people of all ages.
Bright Ampadu +4 more
doaj +2 more sources
Onchocerciasis and non-communicable diseases in the Bafut Health District, Cameroon: Knowledge, attitudes, and practices towards community-directed treatment with ivermectin. [PDF]
BackgroundOnchocerciasis remains a public health problem in Cameroon despite years of community-directed treatment with ivermectin (CDTI). Its persistence increasingly overlaps with the rising burden of non-communicable diseases (NCDs).
Irene U Ajonina-Ekoti +10 more
doaj +2 more sources
IntroductionOnchocerciasis, a neglected tropical disease of public health importance, causes chronic morbidity and severe disability that may impact on health-related quality of life (HRQoL) of the infected people.
Adah E Otache +5 more
doaj +2 more sources
Background The presence of breeding sites and distribution of species of Simulium damnosum sensu lato are critical in understanding the epidemiology of onchocerciasis and evaluating the impact of elimination interventions.
Franklin Ayisi +7 more
doaj +1 more source

