Results 41 to 50 of about 7,724 (174)

Spatial clustering of onchocerciasis in Bioko Island, Equatorial Guinea

Journal of Infection in Developing Countries, 2018
Introduction: Onchocerciasis is a chronic neglected tropical disease caused by the filarial nematode Onchocerca volvulus, which is endemic in Equatorial Guinea.
Diana Gómez-Barroso, Laura Moya, Zaida Herrador, Belén García, Justino Nguema, Policarpo Ncogo, Pilar Aparicio, Agustín Benito   +7 more
doaj   +1 more source

The Potential of Bioinformatics in Revolutionizing Disease Diagnosis in Sub‐Saharan Africa: A Narrative Review

Health Science Reports, Volume 9, Issue 4, April 2026.
ABSTRACT Background and Aim Despite its role in healthcare delivery and accessibility, the potential of bioinformatics to transform disease diagnosis in SSA remains unknown. This narrative review aims to assess the current status of bioinformatics initiatives in SSA and evaluate the role of bioinformatics in transforming diagnosis of major diseases in ...
Wilfred Ofosu, Fleischer C. N. Kotey, Alex Odoom, Onyansaniba K. Ntim, Eric S. Donkor   +4 more
wiley   +1 more source

Evolution of Ivermectin Resistance in the Nematode Model Caenorhabditis elegans: Critical Influence of Population Size and Altered Emodepside Efficacy

Evolutionary Applications, Volume 19, Issue 4, April 2026.
ABSTRACT The emergence and spread of anthelmintic resistance represent a major challenge for treating parasitic nematodes, threatening mass‐drug administration control programs in humans and zoonotic hosts. Currently, experimental evidence to understand the influence of management (e.g., treatment dose and frequency) and parasite‐associated factors (e ...
Jacqueline Hellinga, Barbora Trubenova, Jessica Wagner, Marc Borchert, Jürgen Krücken, Roland R. Regoes, Hinrich Schulenburg, Georg von Samson‐Himmelstjerna   +7 more
wiley   +1 more source

From Aid Dependency to Self‐Reliance: Lessons From Sierra Leone and Rwanda's Strategies for Eliminating Preventable Blindness in Africa: A Perspective Study

Health Science Reports, Volume 9, Issue 2, February 2026.
ABSTRACT Background and Aims Preventable blindness remains a leading cause of disability in low‐income countries (LICs), with 91.5% of cases in Sierra Leone and 83.9% in Rwanda considered avoidable. Reliance on foreign aid has supported eye care development in Africa, yet has also fostered systemic dependency.
Babatunde Ismail Bale, Lynette Delali Amematekpor, Ebunoluwa Anne Ajibola‐Ajo, Seriki Yetunde Mutiat, Ojo Onakhe Emmanuel, Adeleke Oluwatimilehin   +5 more
wiley   +1 more source

An appraisal of the neglected tropical diseases control program in Cameroon: the case of the national program against onchocerciasis

BMC Public Health, 2017
Background Onchocerciasis is a severe parasitic infestation which causes disabling skin and subcutaneous tissue changes. Current global estimates suggest that it accounts for 1135.7 disability adjusted life years (DALYs) per 100,000 population.
Tsi Njim, Leopold Ndemnge Aminde
doaj   +1 more source

Molecular Screening of Black Flies (Diptera: Simuliidae) for Vector‐Borne Zoonotic Pathogens, South Moravia, Czech Republic

Zoonoses and Public Health, Volume 73, Issue 1, Page 95-106, February 2026.
ABSTRACT Introduction Black flies (Simuliidae) are globally distributed blood‐feeding arthropods and vectors of viral, bacterial, and parasitic pathogens to many animal species, including humans. We investigated the occurrence of selected vector‐borne pathogens in black flies in South Moravia, Czech Republic, and evaluated their possible role in the ...
Silvie Šikutová, Kristína Mravcová, Jan Mendel, Oldřich Šebesta, Bohumil Sak, Nikola Holubová, Martin Kváč, Clifton McKee, Peter H. Adler, D. Otranto, Ivo Rudolf   +10 more
wiley   +1 more source

Assessment of community’s knowledge, attitude and practice about onchocerciasis and community directed treatment with Ivermectin in Quara District, north western Ethiopia

Parasites & Vectors, 2014
Background The African Program for Onchocerciasis Control (APOC) has been working with ultimate goal of reducing the public health and socio-economic problems associated with onchocerciasis within a period of 12–15 years.
Fitsum Weldegebreal, Girmay Medhin, Zemichael Weldegebriel, Mengistu Legesse   +3 more
doaj   +1 more source

Tolerability, Safety, and Pharmacokinetics of Ivermectin After Nasal Application in Healthy Adult Subjects

The Journal of Clinical Pharmacology, Volume 66, Issue 1, January 2026.
Abstract Nasal epithelium is the site of infection for SARS‐CoV2 viruses, with interactions of the viral spike protein with the ACE2 receptor of the host cell. Molecular docking studies have shown that ivermectin shields the spike protein and thereby prevents binding to ACE2.
Stefan Wissel, Philipp Wissel, Matthias Rischer, Felix Häberlein, Hilde Riethmüller‐Winzen, Hanns Häberlein   +5 more
wiley   +1 more source

Chemical Composition and Binary Combination Effect of Citrus sinensis (Rutaceae) and Callistemon rigidus (Myrtaceae) Essential Oils Against the Malarial Vector Anopheles gambiae s.l. (Diptera: Culicidae)

International Journal of Zoology, Volume 2026, Issue 1, 2026.
Mosquito vector elimination using botanicals is recommended nowadays because they are biodegradable and less harmful to humans and nontarget organisms. In this context, binary combinations of Citrus sinensis and Callistemon rigidus essential oils were assayed against the larvae and adults of Anopheles gambiae in the laboratory.
Lame Younoussa, Farida Lacmago Longmou, Kary Mallam Oumarou, Mamat Amina, Katamssadan Haman Tofel, Aurelie Dadji Foko, Abraham Fomena, Charles Okechukwu Esimone, Elias Nchiwan Nukenine, Laxman Khanal   +9 more
wiley   +1 more source

Hidden in Plain Sight: The Enduring Challenge of Neglected Tropical Diseases in Khartoum State, Sudan

Journal of Tropical Medicine, Volume 2026, Issue 1, 2026.
Background Neglected tropical diseases (NTDs) disproportionately affect impoverished populations in tropical regions. Despite their significant health burden, data on NTD prevalence and distribution are limited in many areas, including Khartoum State, Sudan.
Babiker Mohamed Rahamtalla, Max Carlos Ramirez-Soto   +1 more
wiley   +1 more source