Results 51 to 60 of about 11,845 (228)

The neglected majority: Inverse relationship between prevalence and global research activity of 15 dermatological diseases

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 24, Issue 4, Page 538-540, April 2026.
Oliver Brandt, Erere Otrofanowei, Ncoza Dlova, Simon M. Mueller   +3 more
wiley   +1 more source

A Case of Creeping Disease Caused by Gnathostoma in a Pregnant Woman Treated With Ivermectin

Clinical Case Reports, Volume 13, Issue 9, September 2025.
During pregnancy, the patient had eaten raw freshwater fish on multiple occasions and caused creeping disease by Gnathostoma. The administration of antiparasitic drugs during pregnancy must be carefully considered based on the gestational age, severity of symptoms, fetal condition, and patient preferences.
Sonoka Uchida, Hidetoshi Maruyama, Yoshihito Yokoyama   +2 more
wiley   +1 more source

Recognising the neurological burden of onchocerciasis: the need to include onchocerciasis-associated epilepsy in onchocerciasis global health metrics

Infectious Diseases of Poverty
Background Historically, onchocerciasis has been recognised for its dermatological and ophthalmological manifestations, such as blindness. However, growing epidemiological evidence indicates that onchocerciasis is also associated with neurological ...
Luís-Jorge Amaral, Robert Colebunders
doaj   +1 more source

Targeting Mitogen‐Activated Protein Kinase‐Activating Death Domain Protein of Brugia malayi for Construction of a Multi‐Epitope Subunit Vaccine Against Lymphatic Filariasis

Medicine Advances, Volume 3, Issue 3, Page 177-192, September 2025.
We focused on the MAP kinase activating death domain (MADD) protein of Brugia malayi as a candidate for a vaccine against lymphatic filariasis (LF). Our results demonstrated a significant increase in the production of memory B‐cells, T‐cells, and antibodies, which are crucial for removing microfilariae from the circulation of infected individuals. This
Paa Kwesi Anfu, Gifty Madjitey, Jennifer Afreh, Arnold Abakah, Prince Dunyo, Prince Manu, Kweku Foh Gyasi, Priscilla Osei‐Poku, Alexander Kwarteng   +8 more
wiley   +1 more source

The Role of Mathematical Modelling in Predicting and Controlling Infectious Disease Outbreaks in Underserved Settings: A Systematic Review and Meta‐Analysis

Public Health Challenges, Volume 4, Issue 3, September 2025.
ABSTRACT Background and Aim Mathematical modelling plays an important role in public health by enabling the prediction of disease outbreaks, assessment of transmission dynamics and evaluation of intervention strategies. Although widely applied in high‐resource settings, its use in underserved contexts remains underexplored. This review aimed to examine
Mavhunga Khumbudzo, Evans Duah, Estelle Grobler, Kuhlula Maluleke   +3 more
wiley   +1 more source

Treatment and prevention of epilepsy in onchocerciasis-endemic areas is urgently needed

Infectious Diseases of Poverty
Background There is increasing epidemiological evidence supporting the association between onchocerciasis and seizures, reinforcing the concept of onchocerciasis-associated epilepsy (OAE).
Robert Colebunders, Joseph Nelson Siewe Fodjo, Olivia Kamoen, Luís-Jorge Amaral, Amber Hadermann, Chiara Trevisan, Mark J. Taylor, Julia Gauglitz, Achim Hoerauf, Yasuaki Sato, Katja Polman, María-Gloria Basáñez, Dan Bhwana, Thomson Lakwo, Gasim Abd-Elfarag, Sébastien D. Pion   +15 more
doaj   +1 more source

Developing Strategies for Onchocerciasis Elimination Mapping and Surveillance Through The Diagnostic Network Optimization Approach

, 2021
Heidi Albert, Benn Sartorius, Paul R. Bessell, Dziedzom K. de Souza, Sidharth Rupani, Karla González, Simon Kayembe, Joseph Mathu Ndung’u, Rachel L. Pullan, Don Paul Makana, Maria Cecilia César de Almeida, Naomi Uvon   +11 more
openalex   +1 more source

Barriers to the National Onchocerciasis Control Programme at operational level in Cameroon: a qualitative assessment of stakeholders’ views

Parasites & Vectors, 2019
Background The global burden of onchocerciasis is the heaviest in sub-Saharan Africa. Studies have shown the importance of the role of Community-Directed Distributors (CDDs) and nurses in onchocerciasis control, but little is known about their experience
Fanny Nadia Dissak-Delon, Guy-Roger Kamga, Perrine Claire Humblet, Annie Robert, Jacob Souopgui, Joseph Kamgno, Stephen Mbigha Ghogomu, Isabelle Godin   +7 more
doaj   +1 more source

Repurposing of Anti-Infectives for the Management of Onchocerciasis Using Machine Learning and Protein Docking Studies

Bioinformatics and Biology Insights
There is a need to improve the discovery of new drugs for neglected tropical diseases (NTDs), as the lack of financial incentives has slowed their development. Currently, ivermectin and moxidectin are used in the management of onchocerciasis.
Cyril Tetteh, Andy Andoh Mensah, Bernice Ampomah, Mahmood B Oppong, Michael Lartey, Paul Owusu Donkor, Kwabena FM Opuni, Lawrence A Adutwum   +7 more
doaj   +1 more source

Situation analysis of onchocerciasis in Cameroon: a protocol for systematic review of epidemiological studies and impact of disease control interventions

Systematic Reviews, 2020
Background Many control methods have been implemented to tackle onchocerciasis and great successes have been achieved, leading to a paradigm shift from control of morbidity to interruption of transmission and ultimately elimination.
Hugues C. Nana-Djeunga, André Domche, Yannick Niamsi-Emalio, Henri C. Moungui, Martin Walker, Maria-Gloria Basáñez, Joseph Kamgno   +6 more
doaj   +1 more source