Results 31 to 40 of about 18,365 (214)

Burden of onchocerciasis-associated epilepsy: first estimates and research priorities

Infectious Diseases of Poverty, 2018
Background Since the 1990s, evidence has accumulated of an increased prevalence of epilepsy in onchocerciasis-endemic areas in Africa as compared to onchocerciasis-free areas.
Natalie V. S. Vinkeles Melchers, Sarah Mollenkopf, Robert Colebunders, Michael Edlinger, Luc E. Coffeng, Julia Irani, Trésor Zola, Joseph N. Siewe, Sake J. de Vlas, Andrea S. Winkler, Wilma A. Stolk   +10 more
doaj   +1 more source

Current perspective of new anti-Wolbachial and direct-acting macrofilaricidal drugs as treatment strategies for human filariasis

GMS Infectious Diseases, 2022
Filarial diseases like lymphatic filariasis and onchocerciasis belong to the Neglected Tropical Diseases and remain a public health problem in endemic countries.
Ehrens, Alexandra, Hoerauf, Achim, Hübner, Marc P.   +2 more
doaj   +1 more source

Current Gaps in Survey Design and Analysis for Molecular Xenomonitoring of Vector-Borne Neglected Tropical Diseases: A Systematic Review. [PDF]

Trop Med Int Health
ABSTRACT Objectives Molecular xenomonitoring is a surveillance method for vector‐borne diseases where vectors are tested for molecular pathogen markers. Testing is typically on pools (groups) of vectors. Molecular xenomonitoring is a sensitive and efficient complement to human‐based surveillance.
McLure A, Alamnia T, Xu Z, Lau CL, Mayfield HJ.   +4 more
europepmc   +2 more sources

Development of Onchocerca volvulus in humanized NSG mice and detection of parasite biomarkers in urine and serum. [PDF]

, 2018
BACKGROUND: The study of Onchocerca volvulus has been limited by its host range, with only humans and non-human primates shown to be susceptible to the full life cycle infection.
Abraham, David, Bennuru, Sasisekhar, Eberhard, Mark L., Hess Ligas, Jessica A., Lustigman, Sara, Nutman, Thomas B., Patton, John B., Torigian, April R.   +7 more
core   +3 more sources

Evaluation of Lymphatic Filariasis and Onchocerciasis in Three Senegalese Districts Treated for Onchocerciasis with Ivermectin.

PLoS Neglected Tropical Diseases, 2016
In Africa, onchocerciasis and lymphatic filariasis (LF) are co-endemic in many areas. Current efforts to eliminate both diseases are through ivermectin-based mass drug administration (MDA).
Nana O Wilson, Alioune Badara Ly, Vitaliano A Cama, Paul T Cantey, Daniel Cohn, Lamine Diawara, Abdel Direny, Mawo Fall, Karla R Feeser, LeAnne M Fox, Achille Kabore, Amadou F Seck, Ngayo Sy, Daouda Ndiaye, Christine Dubray   +14 more
doaj   +1 more source

Onchocerciasis control in Ghana (1974–2016)

Parasites & Vectors, 2021
Background The control of onchocerciasis in Ghana started in 1974 under the auspices of the Onchocerciasis Control Programme (OCP). Between 1974 and 2002, a combination of approaches including vector control, mobile community ivermectin treatment, and ...
Nana-Kwadwo Biritwum, Dziedzom K. de Souza, Odame Asiedu, Benjamin Marfo, Uche Veronica Amazigo, John Owusu Gyapong   +5 more
doaj   +1 more source

Predictors of compliance with community-directed ivermectin treatment in Uganda: quantitative results. [PDF]

, 2005
In order to identify the factors influencing compliance with mass ivermectin treatment for onchocerciasis control, a cross-sectional study was carried out in Bushenyi District, Uganda. Data were collected by interviewing 839 individuals who were randomly
Ndyomugyenyi, Richard, Nuwaha, Fred, Okware, Joseph   +2 more
core   +1 more source

Stigma and epilepsy in onchocerciasis-endemic regions in Africa: a review and recommendations from the onchocerciasis-associated epilepsy working group

Infectious Diseases of Poverty, 2019
Background In onchocerciasis-endemic areas, particularly in those with a sub-optimal onchocerciasis control programme, a high prevalence of epilepsy is observed. Both onchocerciasis and epilepsy are stigmatizing conditions.
Sarah O’Neill, Julia Irani, Joseph Nelson Siewe Fodjo, Denis Nono, Catherine Abbo, Yasuaki Sato, Augustine Mugarura, Housseini Dolo, Maya Ronse, Alfred K. Njamnshi, Robert Colebunders   +10 more
doaj   +1 more source

Advancing a Human Onchocerciasis Vaccine From Antigen Discovery to Efficacy Studies Against Natural Infection of Cattle With Onchocerca ochengi

Frontiers in Cellular and Infection Microbiology, 2022
Human onchocerciasis is a devastating neglected tropical disease caused by infection of the filarial nematode Onchocerca volvulus. The infection can cause irreversible visual impairment or blindness and stigmatizing dermatitis.
Bin Zhan, Maria Elena Bottazzi, Peter J. Hotez, Sara Lustigman   +3 more
doaj   +1 more source

Host, vector, and parasite dynamics: exploring intrinsic and extrinsic factors shaping tick‐borne filarial nematode transmission

Biological Reviews, EarlyView.
ABSTRACT Tick‐borne filarial nematodes are a complex and understudied group of parasites that rely on ticks for transmission in vertebrates. This review examines how intrinsic and extrinsic factors may influence the successful transmission of filarial nematodes in tick vectors, drawing insights from extensively studied haematophagous dipteran vector ...
Oluwaseun D. Ajileye, Gabriel L. Hamer, Sarah A. Hamer, Guilherme G. Verocai, Jessica E. Light   +4 more
wiley   +1 more source