Modelling of onchocerciasis-associated skin and ocular disease and the impact of ivermectin treatment [PDF]
Communications MedicineBackground Despite decades of control interventions in sub-Saharan Africa, morbidity associated with Onchocerca volvulus infection still exerts a substantial burden of disease, arising from cutaneous, ocular and neurological manifestations.
Matthew A. Dixon +8 more
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Modelling the impact of ivermectin on River Blindness and its burden of morbidity and mortality in African Savannah: EpiOncho projections [PDF]
Parasites & Vectors, 2014 Background The African Programme for Onchocerciasis Control (APOC) has refocused its goals on the elimination of infection where possible, seemingly achievable by 15–17 years of annual mass distribution of ivermectin in some African foci.
Hugo C Turner +3 more
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Elimination of onchocerciasis in Ecuador: findings of post-treatment surveillance [PDF]
Parasites & Vectors, 2018 Background The Esmeraldas focus of onchocerciasis in Ecuador expanded geographically during the 1980s and was associated with severe ocular and skin disease. Mass drug administration (MDA) with ivermectin started in 1991, initially once but later twice a
Ángel Guevara +6 more
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Onchocerciasis overview: pathogenesis, clinical spectrum, and therapeutic challenges of a neglected tropical disease [PDF]
Frontiers in ParasitologyOnchocerciasis is still a major health burden in sub-Saharan Africa and Yemen, where many cases occur as control efforts face persistent obstacles, while smaller, well-defined transmission foci remain in Brazil and Venezuela.
Charity N. Njeshi +2 more
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Onchocerciasis is not a major cause of blindness in two endemic villages in Sierra Leone [PDF]
BMC Research NotesObjective Sierra Leone, a country where onchocerciasis is endemic in 14 of the 16 districts, was the focus of our investigation. Despite 17 rounds of annual ivermectin treatment since 2005, a report circulated by a local politician indicated an increase ...
Ibrahim Kargbo-Labour +10 more
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, 1974 A case report of a patient who was admitted to the City Hospital, Edinburgh in September 1974 is described. The patient who while on vacation in Ibadan, Nigeria had been feeling generally unwell, and for several months had transient acute ocular symptoms
Coleiro, Joseph A.
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Sustainable control of onchocerciasis: ocular pathology in onchocerciasis patients treated annually with ivermectin for 23 years: a cohort study. [PDF]
PLoS ONE, 2014 UnlabelledThe evolution and persistence of ocular pathology was assessed in a cohort of Onchocerca volvulus infected patients treated annually with ivermectin for 23 years.
Méba Banla +9 more
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The Spectrum of Ocular Diseases in the Onchocerciasis-Endemic Focus of Raga in South Sudan [PDF]
Research and Reports in Tropical MedicineKenneth Lado Sube,1 Joseph Daniel Wani Lako,2 Justin Bruno Tongun,3 Tatjana Gerber,4 Jurel Payii Mamur,4 Sekonjo Juliano Hamid Moto,4 Stephen Raimon Legge Jada,5 Joseph Nelson Siewe Fodjo,6 Adrian Dennis Hopkins,7 Charles D Mackenzie,8,9 Robert ...
Sube KL +10 more
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A cross-sectional investigation of the ophthalmological impact of loiasis in Cameroon, Central Africa. [PDF]
PLoS Neglected Tropical DiseasesBackgroundCurrent knowledge of ocular manifestations of loiasis is limited to the transient subconjunctival passage of the adult filaria and anecdotal reports of posterior segment lesions.
Joseph Kamgno +10 more
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Ocular onchocerciasis: current management and future prospects
Clinical Ophthalmology, 2011 Olufemi Emmanuel Babalola Department of Ophthalmological Surgery, Bingham University Teaching Hospital, New Karu, Nassarawa State, Nigeria Abstract: This paper reviews the current management of onchocerciasis and its future prospects. Onchocerciasis is a
Babalola OE
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