Results 21 to 30 of about 18,365 (214)

Onchocerciasis Prevalence among Persons with Epilepsy in an Onchocerciasis Hypo-Endemic Area in the Democratic Republic of Congo: A Cross-Sectional Study

Pathogens, 2021
A high epilepsy prevalence has been reported in onchocerciasis meso- and hyper-endemic regions in sub-Saharan Africa, including in the Democratic Republic of Congo (DRC). We investigated whether onchocerciasis-associated epilepsy can also be suspected in
An Hotterbeekx, Kristien Verdonck, Deby Mukendi, Jean-Roger Lilo-Kalo, Pascal Lutumba, Marleen Boelaert, Liselotte Hardy, Barbara Barbé, Jan Jacobs, Emmanuel Bottieau, Robert Colebunders   +10 more
doaj   +1 more source

The geographic distribution of onchocerciasis in the 20 participating countries of the African Programme for Onchocerciasis Control: (2) pre-control endemicity levels and estimated number infected

Parasites & Vectors, 2014
Background The original aim of the African Programme for Onchocerciasis Control (APOC) was to control onchocerciasis as a public health problem in 20 African countries.
Honorat GM Zouré, Mounkaila Noma, Afework H Tekle, Uche V Amazigo, Peter J Diggle, Emanuele Giorgi, Jan HF Remme   +6 more
doaj   +1 more source

Nodding syndrome research, lessons learned from the NSETHIO project

Cambridge Prisms: Global Mental Health, 2019
Background.Until recently, nodding syndrome (NS) was considered as a mysterious disease of unknown etiology. A link between onchocerciasis and epilepsy was suspected for a long time.
D. Geelhand de Merxem, J. N. Siewe Fodjo, S. Menon, A. Hotterbeekx, R. Colebunders   +4 more
doaj   +1 more source

Diagnosis of O. volvulus infection via skin exposure to diethylcarbamazine: clinical evaluation of a transdermal delivery technology-based patch

Parasites & Vectors, 2015
Background Elimination of onchocerciasis in Africa is now regarded as an achievable goal in many areas. This makes monitoring changes in infection prevalence a key component of control programmes. Monitoring is currently based on determining the presence
K. Awadzi, Nicholas O. Opoku, Simon K. Attah, Janis K. Lazdins-Helds, Annette C. Kuesel   +4 more
doaj   +1 more source

Stage-specific proteomes from onchocerca ochengi, sister species of the human river blindness parasite, uncover adaptations to a nodular lifestyle [PDF]

, 2016
Despite 40 years of control efforts, onchocerciasis (river blindness) remains one of the most important neglected tropical diseases, with 17 million people affected.
Adam, Altschul, Altschul, Anon, Argueta, Armstrong, Armstrong, Arumugam, Babayan, Bazzocchi, Bendtsen, Benjamini, Bennuru, Bennuru, Berry, Berry, Board, Boatin, Brattig, Brattig, Brophy, Bulman, Burbelo, Burchard, Burket, Butler, Chandrashekar, Chawade, Chhabra, Choi, Claros, Constam, Cooray, Crump, Darby, Darby, Desjardins, Duckert, Edgar, Edwards, Erttmann, Finn, Franceschini, Frank, Gallin, Gardon, GBD 2013 Mortality and Causes of Death Collaborators, Geary, Ghali, Ghedin, Ghosh, Gilbert, Globisch, Godel, Gomez-Escobar, Gopal, Gotenstein, Gottsch, Grainger, Gretes, Guan, Guiliano, Hansen, Henrichfreise, Hewitson, Hewitson, Hewitson, Hotez, Hunter, Ichishita, Joseph, Joza, Kanazawa, Klion, Ko, Koonin, Korten, Krogh, Larkin, Li, Li, Liebau, Liebau, Liebau, Liebau, Littler, Liu, Longo, Lu, Lundquist, Lustigman, Lustigman, Mackenzie, Makepeace, Marti, McGarry, McSorley, Melnikow, Meyer, Michalski, Morales-Hojas, Moreno, Moreno, Morris, Mossmann, Nana-Djeunga, Nfon, Nicholson, Nomura, Ohtsuki, Ohtsuki, Osei-Atweneboana, Page, Pant, Parra, Petersen, Plaisier, Quintana, Ranjan, Rew, Rogalski, Roth, Saitou, Schulz-Key, Schulz-Key, Scocchi, Sheehan, Silva, Sommer, Srivastava, Tamarozzi, Tanikawa, Taylor, Tchakouté, Ternent, Tew, Thompson, Tiwari, Trees, Vogel, Wahl, Waterhouse, Westermann, Wildenburg, Willenbucher, Wilson, Wisniewski, Wu, Wu, Xie, Xie, Yamaguchi, Yang, Yasuda, Zanetti, Zipfel   +155 more
core   +6 more sources

Mass Drug Administration and beyond: how can we strengthen health systems to deliver complex interventions to eliminate neglected tropical diseases? [PDF]

, 2015
Achieving the 2020 goals for Neglected Tropical Diseases (NTDs) requires scale-up of Mass Drug Administration (MDA) which will require long-term commitment of national and global financing partners, strengthening national capacity and, at the community ...
Adams, ER, Bockarie, MJ, Harrison, RA, Hollingsworth, T, Kelly-Hope, LA, Kovacic, V, Lehane, M, Macpherson, EE, Paine, MJI, Reimer, LJ, Torr, SJ   +10 more
core   +1 more source

Elimination of onchocerciasis in Africa by 2025: an ambitious target requires ambitious interventions

Infectious Diseases of Poverty, 2019
To achieve the elimination of onchocerciasis transmission in all African countries will entail enormous challenges, as has been highlighted by the active discussion around onchocerciasis intervention strategies and evaluation procedures in this journal ...
Robert Colebunders, Wilma A. Stolk, Joseph Nelson Siewe Fodjo, Charles D. Mackenzie, Adrian Hopkins   +4 more
doaj   +1 more source

Measurement of circulating filarial antigen levels in human blood with a point-of-care test strip and a portable spectrodensitometer [PDF]

, 2016
The Alere Filariasis Test Strip (FTS) is a qualitative, point-of-care diagnostic tool that detects Wuchereria bancrofti circulating filarial antigen (CFA) in human blood, serum, or plasma.
Awaca-Uvon, Naomi-Pitchouna, Boussinesq, Michel, Chesnais, Cédric B, Kunyu-Shako, Billy, Mumba, Dieudonné, Pion, Sébastien D, Vlaminck, Johnny, Weil, Gary J   +7 more
core   +2 more sources

Is onchocerciasis elimination in Africa feasible by 2025: a perspective based on lessons learnt from the African control programmes

Infectious Diseases of Poverty, 2018
Background Onchocerciasis is found predominantly in Africa where large scale vector control started in 1974. Registration and donation of ivermectin by Merck & Co in 1987 enabled mass treatment with ivermectin in all endemic countries in Africa and the ...
Yankum Dadzie, Uche V. Amazigo, Boakye A. Boatin, Azodoga Sékétéli   +3 more
doaj   +1 more source

Pharmacokinetics, safety, and efficacy of a single co-administered dose of diethylcarbamazine, albendazole and ivermectin in adults with and without Wuchereria bancrofti infection in Cote d\u27Ivoire [PDF]

, 2019
BackgroundA single co-administered dose of ivermectin (IVM) plus diethylcarbamazine (DEC) plus albendazole (ALB), or triple-drug therapy, was recently found to be more effective for clearing microfilariae (Mf) than standard DEC plus ALB currently used ...
Bjerum, Catherine M, Chhonker, Yashpal S, Edi, Constant, King, Christopher L, Koudou, Benjamin G, Meite, Aboulaye, Murry, Daryl J, Ouattara, Allassane F, Penali, Louis K, Weil, Gary J   +9 more
core   +4 more sources