Results 21 to 30 of about 7,724 (174)

Is onchocerciasis elimination in Africa feasible by 2025: a perspective based on lessons learnt from the African control programmes

Infectious Diseases of Poverty, 2018
Background Onchocerciasis is found predominantly in Africa where large scale vector control started in 1974. Registration and donation of ivermectin by Merck & Co in 1987 enabled mass treatment with ivermectin in all endemic countries in Africa and the ...
Yankum Dadzie, Uche V. Amazigo, Boakye A. Boatin, Azodoga Sékétéli   +3 more
doaj   +1 more source

Burden of onchocerciasis-associated epilepsy: first estimates and research priorities

Infectious Diseases of Poverty, 2018
Background Since the 1990s, evidence has accumulated of an increased prevalence of epilepsy in onchocerciasis-endemic areas in Africa as compared to onchocerciasis-free areas.
Natalie V. S. Vinkeles Melchers, Sarah Mollenkopf, Robert Colebunders, Michael Edlinger, Luc E. Coffeng, Julia Irani, Trésor Zola, Joseph N. Siewe, Sake J. de Vlas, Andrea S. Winkler, Wilma A. Stolk   +10 more
doaj   +1 more source

Repurposing Oxfendazole for Onchocerciasis: Population Pharmacokinetics of a Tablet Formulation in Healthy African Adults. [PDF]

CPT Pharmacometrics Syst Pharmacol
ABSTRACT Global efforts to eliminate onchocerciasis are hampered by the lack of a macrofilaricidal drug capable of killing adult parasites. Oxfendazole, a veterinary anthelminthic, exhibits macrofilaricidal activity and holds promise to shorten treatment durations.
Assmus F, Adehin A, Hoglund RM, Nyaulingo G, Mbarak H, Jongo S, Ackermann E, Reus E, Keiser J, Rocha FBDS, Specht S, Scandale I, Tarning J.   +12 more
europepmc   +2 more sources

Onchocerciasis control in Ghana (1974–2016)

Parasites & Vectors, 2021
Background The control of onchocerciasis in Ghana started in 1974 under the auspices of the Onchocerciasis Control Programme (OCP). Between 1974 and 2002, a combination of approaches including vector control, mobile community ivermectin treatment, and ...
Nana-Kwadwo Biritwum, Dziedzom K. de Souza, Odame Asiedu, Benjamin Marfo, Uche Veronica Amazigo, John Owusu Gyapong   +5 more
doaj   +1 more source

Stigma and epilepsy in onchocerciasis-endemic regions in Africa: a review and recommendations from the onchocerciasis-associated epilepsy working group

Infectious Diseases of Poverty, 2019
Background In onchocerciasis-endemic areas, particularly in those with a sub-optimal onchocerciasis control programme, a high prevalence of epilepsy is observed. Both onchocerciasis and epilepsy are stigmatizing conditions.
Sarah O’Neill, Julia Irani, Joseph Nelson Siewe Fodjo, Denis Nono, Catherine Abbo, Yasuaki Sato, Augustine Mugarura, Housseini Dolo, Maya Ronse, Alfred K. Njamnshi, Robert Colebunders   +10 more
doaj   +1 more source

Current perspective of new anti-Wolbachial and direct-acting macrofilaricidal drugs as treatment strategies for human filariasis

GMS Infectious Diseases, 2022
Filarial diseases like lymphatic filariasis and onchocerciasis belong to the Neglected Tropical Diseases and remain a public health problem in endemic countries.
Ehrens, Alexandra, Hoerauf, Achim, Hübner, Marc P.   +2 more
doaj   +1 more source

Community Health Workers' Multiple Understandings of Schistosomiasis Transmission Pathways: Exploring Contextual Factors in Côte d'Ivoire, Kenya and Uganda

Tropical Medicine &International Health, EarlyView.
ABSTRACT Objective Schistosomiasis remains a public health concern in sub‐Saharan Africa, affecting over 250 million people. In endemic settings, schistosomiasis transmission is not always understood exclusively in biomedical terms. Community health workers (CHWs) contribute to schistosomiasis control through mass drug administration and health ...
Dianne Verhoeven, Lisa Sophie Reigl, Alice Sereti Sinkeet, Mary Maghanga, Alexise Djouquou Gnahore, Bi Tra Jamal Sehi, Suzanne Lobohon Lavry, Andrea Buhl, Marie Frese, Jennifer Burrill, Eveline Hürlimann, Peter Steinmann, Nora Monnier, Ashley Preston, Janet Masaku, Matthias Richter, Mary Amuyunzu Nyamongo, Alain Toh, Stella Neema, Isabelle L. Lange, Andrea S. Winkler, on behalf of the Pediatric Praziquantel Consortium   +21 more
wiley   +1 more source

Advancing a Human Onchocerciasis Vaccine From Antigen Discovery to Efficacy Studies Against Natural Infection of Cattle With Onchocerca ochengi

Frontiers in Cellular and Infection Microbiology, 2022
Human onchocerciasis is a devastating neglected tropical disease caused by infection of the filarial nematode Onchocerca volvulus. The infection can cause irreversible visual impairment or blindness and stigmatizing dermatitis.
Bin Zhan, Maria Elena Bottazzi, Peter J. Hotez, Sara Lustigman   +3 more
doaj   +1 more source

Increased Risk of Environmental and Endemic Infectious Diseases in Sjögren's Disease: A Retrospective Analysis (2015–2023)

ACR Open Rheumatology, Volume 8, Issue 8, August 2026.
Objective Sjögren's disease (SjD) is a chronic autoimmune disease with a complex etiology, where pathogens may influence disease development or progression. Although SjD is not communicable, environmental and endemic pathogen exposures may influence its onset or progression.
Swetha K. Shankar, Taylor C. Boone, Eliza C. Diggins, Melodie L. Weller   +3 more
wiley   +1 more source

Dipteran succession on decomposing domestic pig carcasses in a rural area of southeastern Brazil

Scientific Reports
Diptera plays a pivotal role in forensic investigations, particularly in estimating the post-mortem interval. This can be achieved by analyzing the succession patterns of species on decomposing bodies, which requires detailed knowledge of the local fauna.
Carlos Henrique Garção-Neto, Lucas Barbosa Cortinhas, Paloma Martins Mendonça, Marina Lopes Duarte, Renato Tavares Martins, Margareth Maria de Carvalho Queiroz   +5 more
doaj   +1 more source