Results 71 to 80 of about 48,951 (258)

Financial and economic costs of the elimination and eradication of onchocerciasis (river blindness) in Africa [PDF]

, 2015
Onchocerciasis (river blindness) is a parasitic disease transmitted by blackflies. Symptoms include severe itching, skin lesions, and vision impairment including blindness. More than 99% of all cases are concentrated in sub-Saharan Africa.
Sicuri, E, Young Eun Kim (117995), Elisa Sicuri, Sicuri, Elisa, Tediosi, F, Fabrizio Tediosi (247282), Young Eun Kim, Tediosi, Fabrizio, Young Eun Kim, Fabrizio Tediosi, Kim, Young E., Elisa Sicuri (247271), Kim, YE, Kim, Young Eun   +13 more
core   +2 more sources

A Roadmap for the Development of Ivermectin as a Complementary Malaria Vector Control Tool [PDF]

, 2020
In the context of stalling progress against malaria, resistance of mosquitoes to insecticides, and residual transmission, mass drug administration (MDA) of ivermectin, an endectocide used for neglected tropical diseases (NTDs), has emerged as a promising
González Silva, Matiana, Chaccour, Carlos, Ruiz Castillo, Paula, The Ivermectin Roadmappers, Rabinovich, Regina   +4 more
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Impact of ivermectin components on Anopheles dirus and Anopheles minimus mosquito survival

Parasites & Vectors
Background Ivermectin mass drug administration to humans or livestock is a potential vector control tool for malaria elimination. Racemic ivermectin is composed of two components, namely a major component (> 80%; ivermectin B1a), which has an ethyl group
Pattarapon Khemrattrakool, Thitipong Hongsuwong, Phornpimon Tipthara, Rattawan Kullasakboonsri, Theerawit Phanphoowong, Patchara Sriwichai, Borimas Hanboonkunupakarn, Podjanee Jittamala, Joel Tarning, Kevin C. Kobylinski   +9 more
doaj   +1 more source

Ivermectin exposures reported to the Poisons Information Helpline in South Africa during the COVID-19 pandemic

South African Medical Journal, 2022
Background. Ivermectin is an antiparasitic drug that has shown in vitro activity against COVID‑19. Clinical studies supporting ivermectin for COVID‑19 prevention and treatment are conflicting, with important limitations. Public support for ivermectin is
V Pillay-Fuentes Lorente, G Voigt, C E du Plessis, K Balme, C J Marks, E H Decloedt, C Stephen, H Reuter, R van Rensburg   +8 more
doaj   +1 more source

Role of ivermectin in the prevention of SARS-CoV-2 infection among healthcare workers in India: A matched case-control study

PLoS ONE, 2021
Background Ivermectin is one among several potential drugs explored for its therapeutic and preventive role in SARS-CoV-2 infection. The study was aimed to explore the association between ivermectin prophylaxis and the development of SARS-CoV-2 infection
P. Behera, B. Patro, A. Singh, P. Chandanshive, Ravikumar S. R., S. Pradhan, S. Pentapati, Gitanjali Batmanabane, P. Mohapatra, B. Padhy, S. Bal, S. Singh, R. Mohanty   +12 more
semanticscholar   +1 more source

Medicines, misinformation and machines: Navigating infodemics in the generative AI era

British Journal of Clinical Pharmacology, EarlyView.
Health information is now widely accessed through smartphones, online searches and increasingly through generative artificial intelligence (AI). These systems create new opportunities for communication, and in some routine contexts, well‐governed AI assistants could reduce exposure to lower quality sources by providing cautious, evidence‐aligned ...
Natansh D. Modi, Lisa M. Kalisch Ellett, Michael D. Wiese, Ashley M. Hopkins   +3 more
wiley   +1 more source

Comparative effect of dose escalation of nanocapsulated ivermectin against mange in rabbits

German Journal of Veterinary Research, 2022
The present study aimed to investigate the effects of nano-capsulated ivermectin on the liver and kidney function and oxidative status in mite infested-rabbits, compared to ivermectin. Additionally, the ivermectin residue profile in adipose tissue, liver,
Azza Abdelmoteleb, Dalia Elmasry, Fatma Amro, Reham Mahmoud   +3 more
doaj   +1 more source

A systematic review and an individual patient data meta-analysis of ivermectin use in children weighing less than fifteen kilograms: Is it time to reconsider the current contraindication?

PLoS Neglected Tropical Diseases, 2021
Background Oral ivermectin is a safe broad spectrum anthelminthic used for treating several neglected tropical diseases (NTDs). Currently, ivermectin use is contraindicated in children weighing less than 15 kg, restricting access to this drug for the ...
P. Jittamala, W. Monteiro, M. R. Smit, Bélen Pedrique, S. Specht, Carlos J. Chaccour, C. Dard, P. del Giudice, Virak Khieu, A. Maruani, Virgilio E. Failoc-Rojas, M. Sáez‐de‐Ocariz, A. Soriano-Arandes, J. Piquero-Casals, A. Faisant, M. Brenier-Pinchart, David Wimmersberger, J. Coulibaly, J. Keiser, F. Boralevi, O. Sokana, M. Marks, Daniel Engelman, L. Romani, A. Steer, L. von Seidlein, N. White, E. Harriss, K. Stepniewska, G. Humphreys, K. Kennon, P. Guérin, K. Kobylinski   +32 more
semanticscholar   +1 more source

Long‐Acting Therapeutics in Pediatric Health: Bridging Innovation and Access

Clinical Pharmacology &Therapeutics, EarlyView.
Children have distinct therapeutic needs arising from age‐dependent physiology, disease epidemiology, formulation requirements, dosing considerations, and safety vulnerabilities. Despite substantial reductions in childhood mortality over the past three decades, nearly 5 million children under five died in 2023, with infectious diseases continuing to ...
Prajith Venkatasubramanian, Moherndran Archary, Daniel B. Hawcutt, Rachel Daley, Edmund Capparelli, Adeniyi Olagunju   +5 more
wiley   +1 more source

Ivermectin tartalmú innovatív készítmények fomulálása és vizsgálata

, 2022
Kutatási munkám célja egy stabil, ivermectint tartalmazó önemulgeáló rendszer létrehozása volt, amely az ivermectin oldatos formájához képest nagyobb biológiai hatékonysággal (ölési képességgel) rendelkezik.
Koterlán, Dávid
core