Results 71 to 80 of about 46,297 (216)

Ivermectin inhibits canine mammary tumor growth by regulating cell cycle progression and WNT signaling

open access: yesBMC Veterinary Research, 2019
Background Mammary gland tumor is the most common spontaneous tumor in intact female dogs, and its poor prognosis remains a clinical challenge. Ivermectin, a well-known anti-parasitic agent, has been implicated as a potential anticancer agent in various ...
Hongxiu Diao   +7 more
doaj   +1 more source

Functional Characterization of the Cat and Dog Wild‐Type and Mutant MDR1 Carrier Proteins and Frequency of the MDR1 Gene Mutation in 800 Cats From Germany

open access: yesJournal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT The ATP‐binding cassette transporter MDR1 P‐glycoprotein (syn. ABCB1) is an efflux carrier at the cell membrane that regulates drug absorption, distribution, and elimination. At the blood–brain barrier, MDR1 restricts brain entry of potentially neurotoxic drugs, such as ivermectin. In dogs and cats, MDR1 (syn.
Lisa Siegl   +6 more
wiley   +1 more source

Presence of the ABCB1 (MDR1) deletion mutation causing ivermectin hypersensitivity in certain dog breeds in Belgium [PDF]

open access: yes, 2009
Hypersensitivity to ivermectin and certain other drugs in Collies and related breeds is caused by a 4-base pair deletion mutation in the ABCB1 gene, better known as the MDR1 gene, encoding P-glycoprotein.
Daminet, Sylvie   +9 more
core   +2 more sources

Ingestion of attractive toxic sugar baits containing ivermectin before and after blood feeding affects the biology and reproduction of Aedes aegypti (Diptera: Culicidae)

open access: yesMedical and Veterinary Entomology, EarlyView.
Attractive toxic sugar bait containing ivermectin (ATSB‐IVM) ingestion markedly reduced blood feeding, survival, oviposition, egg production and larval hatching, with the strongest effects when baits were ingested before blood feeding. Timing of ingestion (48–96 h before or after blood feeding) shaped sublethal impacts across the first and second ...
Thais Alves de Moura   +2 more
wiley   +1 more source

A case of Scalp Rosacea treated with low dose doxycycline and probiotic therapy and literature review on therapeutic options [PDF]

open access: yes, 2016
Rosacea is a common chronic inflammatory disorder showing a wide range of clinical features such as telangiectasia, erythema, papules, and pustules primarily involving the central part of face (forehead, cheeks and nose) although extra facial ...
Cardone, Michele   +6 more
core   +1 more source

Drivers of Noncompliance With Vaccine Mandates—The Interplay Between Distrust, Rationality, Morality, and Social Motivation

open access: yesRegulation &Governance, EarlyView.
ABSTRACT COVID‐19 amplified the issue of public resistance to government vaccination programs. Little attention has focused on people's moral reasons for noncompliance, which differ from—but often build upon—the epistemic claims they make about vaccine safety and efficacy, disease severity, and the trustworthiness of government. This study explores the
Katie Attwell   +4 more
wiley   +1 more source

Structural model, functional modulation by ivermectin and tissue localization of Haemonchus contortus P-glycoprotein-13

open access: yesInternational Journal for Parasitology: Drugs and Drug Resistance, 2018
Haemonchus contortus, one of the most economically important parasites of small ruminants, has become resistant to the anthelmintic ivermectin. Deciphering the role of P-glycoproteins in ivermectin resistance is desirable for understanding and overcoming
Marion David   +8 more
doaj   +1 more source

Lack of efficacy of standard doses of ivermectin in severe COVID-19 patients.

open access: yesPLoS ONE, 2020
Ivermectin has recently shown efficacy against SARS-CoV-2 in-vitro. We retrospectively reviewed severe COVID-19 patients receiving standard doses of ivermectin and we compared clinical and microbiological outcomes with a similar group of patients not ...
Daniel Camprubí   +8 more
doaj   +1 more source

Proceedings of a Joint Meeting held between The Norwegian Society of Infectious Diseases and the Royal Society of Tropical Medicine and Hygiene, Oslo, 20th June 2008 [PDF]

open access: yes, 2009
The Royal Society of Tropical Medicine and Hygiene (RSTMH) has a tradition of holding joint meetings with fellow European Societies, providing opportunities to facilitate discussion, exchange information, foster mutual interests and develop collaboration
Myrvang, Bjorn, Newport, Melanie J.
core   +1 more source

Dupilumab‐Associated Palmar Erythema Successfully Treated With Fluconazole

open access: yes
Australasian Journal of Dermatology, EarlyView.
Katina J. Selvaraj, Geoffrey Lee
wiley   +1 more source

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