Results 81 to 90 of about 48,951 (258)

Comparison between the efficacy of ivermectin and other drugs in treatment of cutaneous leishmaniasis [PDF]

Iraqi Journal of Veterinary Sciences, 2009
The study was conducted to compare the efficacy of ivermectin with some drugs in treatment of cutaneous leishmaniasis in vitro and in Balb/ C mice. The cultivation of Leishmania tropica was done on Nove MacNeal-Nicole medium (NNN).
M. A. Kadir, H. S. Aswad, A. M. Al-Samarai and G. A. Al-Mula
doaj   +1 more source

Retracted: Meta-analysis of Randomized Trials of Ivermectin to Treat SARS-CoV-2 Infection

Open Forum Infectious Diseases, 2021
Ivermectin is an antiparasitic drug being investigated for repurposing against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Ivermectin showed in vitro activity against SARS-COV-2, but only at high concentrations.
A. Hill, A. Garratt, J. Levi, J. Falconer, L. Ellis, K. McCann, Victoria Pilkington, A. Qavi, Jun-Zheng Wang, H. Wentzel   +9 more
semanticscholar   +1 more source

Parascaris spp. induced surgical colic in juvenile horses—A Scandinavian perspective

Equine Veterinary Journal, EarlyView.
Abstract Background Parascaris spp. commonly infects foals, and high burdens can cause fatal small intestinal impactions. Progressive anthelmintic resistance poses a risk for an increase of Parascaris spp. related disease in juvenile horses. Objectives To investigate Parascaris‐related surgical intestinal lesions, with special emphasis on ascarid ...
E. Tydén, I. R. Hellings, K. Toft Nielsen, A. Bergren, I. Holmgren, S. Attin, T. Pihl, A. Kendall, Y. Hedberg Alm   +8 more
wiley   +1 more source

Microfilarial distribution of Loa loa in the human host: population dynamics and epidemiological implications. [PDF]

, 2006
Severe adverse events (SAEs) following ivermectin treatment may occur in people harbouring high Loa loa microfilarial (mf) densities. In the context of mass ivermectin distribution for onchocerciasis control in Africa, it is crucial to define precisely ...
Pion, Sébastien, Kamgno, J., Filipe, J.A.N., Gardon, Jacques, Pion, SDS, Boussinesq, Michel, Basanez, M.G., Basáñez, M-G, Boussinesq, M, Gardon, J, Filipe, JAN, Kamgno, J   +11 more
core   +1 more source

Molecular mechanisms of Cys-loop ion channel receptor modulation by ivermectin

Frontiers in Molecular Neuroscience, 2012
Ivermectin is a gold standard anthelmintic drug that works by potently depressing neuronal activity and muscular contractility in arthropods and nematodes. At the molecular level, ivermectin activates inhibitory glutamate-gated chloride channels (GluClRs)
Timothy eLynagh, Joe eLynch
doaj   +1 more source

Effect of a combination of nitazoxanide, ribavirin, and ivermectin plus zinc supplement (MANS.NRIZ study) on the clearance of mild COVID‐19

Journal of Medical Virology, 2021
This trial compared the rate and time of viral clearance in subjects receiving a combination of nitazoxanide, ribavirin, and ivermectin plus Zinc versus those receiving supportive treatment.
H. Elalfy, T. Besheer, A. El-Mesery, A. El-gilany, Mahmoud Abdel-Aziz Soliman, A. Alhawarey, Mohamed Alegezy, Tamer Elhadidy, A. Hewidy, Hossam Zaghloul, M. Neamatallah, Douaa Raafat, Wafaa M. El-Emshaty, Nermin Y. Abo El Kheir, M. El-Bendary   +14 more
semanticscholar   +1 more source

Evidence-based indications for ivermectin in parasitic diseases: An integrated approach to context and challenges in Peru

Parasite Epidemiology and Control, 2023
Ivermectin has emerged as a therapeutic option for various parasitic diseases, including strongyloidiasis, scabies, lice infestations, gnathostomiasis, and myiasis.
Virgilio E. Failoc-Rojas, Heber Silva-Díaz, Jorge L. Maguiña, Alfonso J. Rodriguez-Morales, Cristian Díaz-Velez, Moises Apolaya-Segura, Mario J. Valladares-Garrido   +6 more
doaj   +1 more source

Outcome of ivermectin treated mild to moderate COVID-19 cases: a single-centre, open-label, randomised controlled study

, 2021
Background and objectives: Various existing non-antiviral drugs are being used to treat severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection based mostly on existing data from previous coronavirus outbreaks.
C. Podder, N. Chowdhury, M. Sina, W. Haque   +3 more
semanticscholar   +1 more source

Advancing pharmacometrics in Africa—Transition from capacity development toward job creation

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 407-419, March 2025.
Abstract Trained pharmacometricians remain scarce in Africa due to limited training opportunities, lack of a pharmaceutical product development ecosystem, and emigration to high‐income countries. The Applied Pharmacometrics Training (APT) fellowship program was established to address these gaps and specifically foster job creation for talent retention.
Goonaseelan (Colin) Pillai, Samer Mouksassi, Innocent G. Asiimwe, Craig R. Rayner, Steven Kern, Phumla Sinxadi, Paolo Denti, Eric Decloedt, Catriona Waitt, Bernhards R. Ogutu, Rik de Greef   +10 more
wiley   +1 more source

Lymphatic Filariasis Control in Tanzania: Effect of Six Rounds of Mass Drug Administration with Ivermectin and Albendazole on Infection and Transmission. [PDF]

, 2013
Control of lymphatic filariasis (LF) in most countries of sub-Saharan Africa is based on annual mass drug administration (MDA) with a combination of ivermectin and albendazole, in order to interrupt transmission. We present findings from a detailed study
Simonsen, Paul E, Mwele N Malecela, Derua, Yahya A, William N Kisinza, Paul E Simonsen, Pedersen, Erling M, Kisinza, William N, Yahya A Derua, Malecela, Mwele N., Derua, Yahya A., Kisinza, William N., Malecela, Mwele N, Magesa, Stephen M., Pedersen, Erling Møller, Stephen M Magesa, Erling M Pedersen, Magesa, Stephen M, Simonsen, Paul Erik   +17 more
core   +2 more sources