Results 101 to 110 of about 48,951 (258)

Efficacy and Safety of Ivermectin for Treatment and prophylaxis of COVID-19 Pandemic

, 2020
Background: Up-to-date, there is no recognized effective treatment or vaccine for the treatment of COVID-19 that emphasize urgency around distinctive effective therapies.
A. Elgazzar, A.I. Eltaweel, S. A. Youssef, Basma Hany, M. Hafez, Hany Moussa   +5 more
semanticscholar   +1 more source

Tapeworm testing: Coprological and antibody‐based approaches across colic types in a German equine hospital population

Equine Veterinary Education, EarlyView.
Summary Background The association between tapeworm infection and equine colic is established, but gaps remain regarding specific colic types. Objectives To assess the relationship between tapeworm test results and equine colic types: The study aimed to determine if ileocaecal disorders (IC) are more frequently associated with Anoplocephala spp ...
K. L. Adamasky, K. Drozdzewska, P. Schmitz, N. Peczak, K. L. Lightbody, J. B. Matthews, M. K. Nielsen, R. Merle, G. von Samson‐Himmelstjerna, H. Gehlen   +9 more
wiley   +1 more source

Assay strategies for the discovery and validation of therapeutics targeting Brugia pahangi Hsp90 [PDF]

, 2010
The chemotherapy of lymphatic filariasis relies upon drugs such as diethylcarbamazine and ivermectin that largely target the microfilarial stages of the parasite, necessitating continued treatment over the long reproductive life span of the adult worm ...
Gillan, V., O'Neill, K., Devaney, E., Chiosis Gabriela, Kerry O'Neill, Taldone, T., Devaney Eileen, Taldone Tony, Patel, P., O'Neill Kerry, Rodina, A., Kirsty Maitland, Chiosis, G., Maitland Kirsty, Anna Rodina, Rodina Anna, Victoria Gillan, Tony Taldone, Pallav Patel, Gillan Victoria, Sun, W., Eileen Devaney, Patel Pallav, Weilin Sun, Gabriela Chiosis, Maitland, K., Sun Weilin   +26 more
core   +2 more sources

Evaluation of in vitro drug-drug interactions of ivermectin and antimalarial compounds

Malaria Journal
Background Ivermectin is lethal to Anopheles mosquitoes and a novel approach to malaria transmission control. Ivermectin could be co-administered with antimalarial drugs in mass drug administration, seasonal malaria chemoprevention, or other ...
Phornpimon Tipthara, Rattawan Kullasakboonsri, Kevin C. Kobylinski, Joel Tarning   +3 more
doaj   +1 more source

Structural model, functional modulation by ivermectin and tissue localization of Haemonchus contortus P-glycoprotein-13

International Journal for Parasitology: Drugs and Drug Resistance, 2018
Haemonchus contortus, one of the most economically important parasites of small ruminants, has become resistant to the anthelmintic ivermectin. Deciphering the role of P-glycoproteins in ivermectin resistance is desirable for understanding and overcoming
Marion David, Chantal Lebrun, Thomas Duguet, Franck Talmont, Robin Beech, Stéphane Orlowski, François André, Roger K. Prichard, Anne Lespine   +8 more
doaj   +1 more source

Poultry red mite eradication potential of ivermectin and allicin combination treatment

Veterinary Medicine and Science, 2023
Background Existing treatments against poultry red mite (PRM; Dermanyssus gallinae) infestation have reduced efficacy or exhibit hazardous effects on chickens.
JeongWoo Kang, HyunYoung Chae, Md Akil Hossain   +2 more
doaj   +1 more source

Ivermectin as a potential COVID-19 treatment from the pharmacokinetic point of view: antiviral levels are not likely attainable with known dosing regimens

, 2020
The broad-spectrum antiparasitic agent ivermectin has been very recently found to inhibit SARS-CoV-2 in vitro and proposed as a candidate for drug repurposing in COVID-19. In the present report the in vitro antiviral activity end-points are analyzed from
G. Momekov, D. Momekova
semanticscholar   +1 more source

Co-infection with Onchocerca volvulus and Loa loa microfilariae in central Cameroon: are these two species interacting? [PDF]

, 2006
Ivermectin treatment may induce severe adverse reactions in some individuals heavily infected with Loa loa. This hampers the implementation of mass ivermectin treatment against onchocerciasis in areas where Onchocerca volvulus and L.
Pion, SDS, Clarke, P, Basáñez, M-G, Boussinesq, M, Gardon, J, Filipe, JAN, Kamgno, J, J. GARDON, J. A. N. FILIPE, M.-G. BASÁÑEZ, S. D. S. PION, P. CLARKE, J. KAMGNO, M. BOUSSINESQ   +13 more
core   +1 more source

Functional characterization of ivermectin binding sites in α1β2γ2L GABA(A) receptors

Frontiers in Molecular Neuroscience, 2015
GABAA receptors (GABAARs) are the major inhibitory neurotransmitter receptors in the brain and are therapeutic targets for many indications including sedation, anesthesia and anxiolysis.
Argel eEstrada, Joe eLynch
doaj   +1 more source

Diagnosis and Off‐Label Treatment of Subcutaneous Putative Dracunculoid Nematodes in Apteronotus albifrons Originating From Wild‐Caught Fisheries

Journal of Fish Diseases, EarlyView.
ABSTRACT Apteronotus albifrons (Gymnotiformes: Apteronotidae), commonly known as the black ghost knifefish, is a high‐value ornamental fish that is susceptible to various parasites. The affected fish were wild‐caught fisheries and subsequently introduced into a commercial breeding system.
Pedro Henrique Magalhães Cardoso, Simone de Carvalho Balian, Herbert Sousa Soares, Marcelo Bahia Labruna, Gracienhe Gomes dos Santos, José Blanchard Girão Ribeiro Filho, Mauricio Laterça Martins   +6 more
wiley   +1 more source