Results 41 to 50 of about 48,951 (258)

Household-wide ivermectin treatment for head lice in an impoverished community: randomized observer-blinded controlled trial. [PDF]

, 2009
OBJECTIVE: To generate evidence on the effectiveness of household-wide treatment for preventing the transmission of pediculosis capitis (head lice) in resource-poor communities.
Pilger, Daniel, Heukelbach, Jorg, Feldmeier, Hermann, Jorg Heukelbach, Gernot Fengler, Oliveira, Fabiola Araujo, Hermann Feldmeier, Daniel Pilger, Khakban, Adak, Fengler, Gernot, Fabiola Araujo Oliveira, Adak Khakban   +11 more
core   +1 more source

The Approved Dose of Ivermectin Alone is not the Ideal Dose for the Treatment of COVID‐19

medRxiv, 2020
Caly et al.1 reported that ivermectin inhibited severe acute respiratory syndrome‐coronavirus 2 (SARS‐CoV‐2) in vitro for up to 48 hours using ivermectin at 5 μM.
V. Schmith, Jie Zhou, L. Lohmer
semanticscholar   +1 more source

Ivermectin to prevent hospitalizations in patients with COVID-19 (IVERCOR-COVID19) a randomized, double-blind, placebo-controlled trial

BMC Infectious Diseases, 2021
Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) has changed our lives. The scientific community has been investigating re-purposed treatments to prevent disease progression in coronavirus disease (COVID-19) patients.
J. Vallejos, R. Zoni, M. Bangher, S. Villamandos, A. Bobadilla, F. Plano, Claudia Campias, Evangelina Chaparro Campias, M. F. Medina, Fernando Achinelli, H. A. Guglielmone, J. Ojeda, Diego Farizano Salazar, Gerardo Andino, Pablo Kawerin, Silvana Dellamea, A. Aquino, Victor Flores, Carolina N. Martemucci, Silvina María Martinez, J. Segovia, Paola Itati Reynoso, N. Sosa, Mariana Elizabeth Robledo, Joaquina Maria Guarrochena, María Mercedes Vernengo, Natalia Ruiz Diaz, E. Meza, María Gabriela Aguirre   +28 more
semanticscholar   +1 more source

Ivermectin susceptibility and sporontocidal effect in Greater Mekong Subregion Anopheles

Malaria Journal, 2017
Background Novel vector control methods that can directly target outdoor malaria transmission are urgently needed in the Greater Mekong Subregion (GMS) to accelerate malaria elimination and artemisinin resistance containment efforts. Ivermectin mass drug
Kevin C. Kobylinski, Ratawan Ubalee, Alongkot Ponlawat, Chanyapat Nitatsukprasert, Siriporn Phasomkulsolsil, Thanaporn Wattanakul, Joel Tarning, Kesara Na-Bangchang, Patrick W. McCardle, Silas A. Davidson, Jason H. Richardson   +10 more
doaj   +1 more source

Effects of larval exposure to sublethal doses of ivermectin on adult fitness and susceptibility to ivermectin in Anopheles gambiae s.s.

Parasites & Vectors, 2023
Background The effects of ivermectin (endectocide) on mosquito survival make it a potential new malaria vector control tool. The drug can be administered to mosquito disease vectors through blood hosts that include humans and livestock. Its increased use
Caroline Kiuru, Kelly Ominde, Martha Muturi, Lawrence Babu, Caroline Wanjiku, Carlos Chaccour, Marta Ferreira Maia   +6 more
doaj   +1 more source

Ivermectin as a potential drug for treatment of COVID-19: an in-sync review with clinical and computational attributes

Pharmacological Reports, 2021
COVID-19 cases are on surge; however, there is no efficient treatment or vaccine that can be used for its management. Numerous clinical trials are being reviewed for use of different drugs, biologics, and vaccines in COVID-19.
H. Kaur, Nishant Shekhar, Saurabh Sharma, Phulen Sarma, A. Prakash, B. Medhi   +5 more
semanticscholar   +1 more source

The transcriptional response of Caenorhabditis elegans to ivermectin exposure identifies novel genes involved in the response to reduced food intake [PDF]

, 2012
We have examined the transcriptional response of Caenorhabditis elegans following exposure to the anthelmintic drug ivermectin (IVM) using whole genome microarrays and real-time QPCR.
Sai P. Ravikumar, Gilleard John S., John S. Gilleard (183499), Steven T. Laing, Ravikumar, S.P., Sai P. Ravikumar (183489), Laing Roz, Al Ivens, Steven T Laing, Steven T. Laing (183480), Al Ivens (183483), Laing Steven T., Butler Victoria, Debra J. Woods (167740), Sai P Ravikumar, Ravikumar Sai P., Laing, S.T., Woods, D.J., Woods Debra J., Gilleard, J.S., Victoria Butler (183486), Butler, V., Roz Laing, Roz Laing (183493), Laing, R., John S Gilleard, John S. Gilleard, Victoria Butler, Debra J. Woods, Debra J Woods, Ivens, A., Ivens Al   +31 more
core   +2 more sources

Use of Ivermectin Is Associated With Lower Mortality in Hospitalized Patients With Coronavirus Disease 2019

Chest, 2020
Background Ivermectin was shown to inhibit severe acute respiratory syndrome coronavirus 2 replication in vitro, which has led to off-label use, but clinical efficacy has not been described previously.
Juliana Cepelowicz Rajter, M. Sherman, N. Fatteh, F. Vogel, J. Sacks, Jean-Jacques Rajter   +5 more
semanticscholar   +1 more source

Evaluation of the effectiveness and safety of adding ivermectin to treatment in severe COVID-19 patients

BMC Infectious Diseases, 2021
Background and objectives An effective treatment option is not yet available for SARS-CoV2, which causes the COVID-19 pandemic and whose effects are felt more and more every day.
N. Okumuş, Neşe Demirtürk, R. Çetinkaya, Rahmet Güner, I. Avci, S. Orhan, P. Konya, B. Şaylan, A. Karalezli, L. Yamanel, B. Kayaaslan, G. Yılmaz, Ümit Savaşçı, F. Eser, G. Taskin   +14 more
semanticscholar   +1 more source

Actions of Agonists, Fipronil and Ivermectin on the Predominant In Vivo Splice and Edit Variant (RDLbd, I/V) of the Drosophila GABA Receptor Expressed in Xenopus laevis Oocytes [PDF]

, 2014
Ionotropic GABA receptors are the targets for several classes of insecticides. One of the most widely-studied insect GABA receptors is RDL (resistance to dieldrin), originally isolated from Drosophila melanogaster.
Philip Biggin, Suwanmanee, S, Musgaard, M, David Sattelle, Steven David Buckingham, Lees, K, Sattelle, D, Maria Musgaard, Siros Suwanmanee, Kristin Lees, Buckingham, SD, Biggin, P   +11 more
core   +2 more sources