Results 21 to 30 of about 29,185 (219)
Current therapeutic applications and pharmacokinetic modulations of ivermectin [PDF]
Veterinary World, 2019 Ivermectin is considered to be a wonder drug due to its broad-spectrum antiparasitic activity against both ectoparasites and endoparasites (under class of endectocide) and has multiple applications in both veterinary and human medicine.
Khan Sharun +5 more
doaj +1 more source
Integrated analysis reveals FOXA1 and Ku70/Ku80 as targets of ivermectin in prostate cancer
Cell Death and Disease, 2022 Ivermectin is a widely used antiparasitic drug and shows promising anticancer activity in various cancer types. Although multiple signaling pathways modulated by ivermectin have been identified in tumor cells, few studies have focused on the exact target
Shidong Lv +7 more
doaj +1 more source
Permethrin and Ivermectin for Scabies [PDF]
New England Journal of Medicine, 2010 In a remote aboriginal community in tropical northern Australia, a mother comes to the health center with her 4-year-old son, who has multiple sores on the skin of his arms and legs. He is treated with a single dose of intramuscular penicillin G benzathine and with the application of topical 5% permethrin cream over his whole body.
Currie, Bart J., McCarthy, James S.
openaire +4 more sources
Pathogens, 2020 A clinical trial performed in the Democratic Republic of Congo (DRC), among persons with epilepsy (PWE) infected with Onchocerca volvulus treated with anti-seizure medication suggested that ivermectin reduces the seizure frequency. We assessed the effect
Alfred Dusabimana +9 more
doaj +1 more source
Chromatographic Quantification of Ivermectin and Pranziquantel in the Tablets Using Stability Indicating RP-HPLC Method [PDF]
Pharmaceutical Sciences, 2019 Background: A new stability indicating RP-HPLC based assay method was developed to quantify ivermectin and praziquantel simultaneously and applied effectively to tablets.
Naga Venkata Suresh Kumar Devaka +1 more
doaj +1 more source
Rates of microfilarial production by Onchocerca volvulus are not cumulatively reduced by multiple ivermectin treatments. [PDF]
, 2008 Regular distribution of ivermectin reduces onchocerciasis transmission and morbidity by killing, within humans, the microfilarial stage of the parasite (microfilaricidal effect).
Bottomley, Christian +3 more
core +1 more source
Pharmacology Research & Perspectives, 2022 Advanced hepatocellular carcinoma (HCC) results in generally poor clinical outcomes and necessitates better therapeutic strategies. Ivermectin, which is an existing anti‐parasitic drug, has been recently identified as a novel anti‐cancer drug.
Haofeng Lu +7 more
doaj +1 more source
Asian Pacific Journal of Tropical Medicine, 2021 Objective: To evaluate different doses of ivermectin in adult patients with mild COVID-19 and to evaluate the effect of ivermectin on mortality and clinical consequences. Methods: A randomized, double-blind, placebo-controlled, multicenter clinical trial
Morteza Shakhsi Niaee +14 more
doaj +1 more source
Control, elimination, and eradication of river blindness: scenarios, timelines, and ivermectin treatment needs in Africa [PDF]
, 2015 River blindness (onchocerciasis) causes severe itching, skin lesions, and vision impairment including blindness. More than 99% of all current cases are found in sub-Saharan Africa.
Remme, JHF +31 more
core +1 more source
PLoS Pathogens, 2022 The antiparasitic drug ivermectin plays an essential role in human and animal health globally. However, ivermectin resistance is widespread in veterinary helminths and there are growing concerns of sub-optimal responses to treatment in related helminths ...
Roz Laing +12 more
doaj +1 more source