Results 21 to 30 of about 20,717 (141)

Ivermectin susceptibility, sporontocidal effect, and inhibition of time to re-feed in the Amazonian malaria vector Anopheles darlingi

Malaria Journal, 2017
Background Outdoor malaria transmission hinders malaria elimination efforts in the Amazon region and novel vector control tools are needed. Ivermectin mass drug administration (MDA) to humans kills wild Anopheles, targets outdoor-feeding vectors, and can
Kevin C. Kobylinski, Karín S. Escobedo-Vargas, Victor M. López-Sifuentes, Salomón Durand, Edward S. Smith, G. Christian Baldeviano, Robert V. Gerbasi, Sara-Blythe Ballard, Craig A. Stoops, Gissella M. Vásquez   +9 more
doaj   +1 more source

Ivermectin Does Not Protect against SARS-CoV-2 Infection in the Syrian Hamster Model

Microorganisms, 2022
Ivermectin, an FDA-approved antiparasitic drug, has been reported to have in vitro activity against SARS-CoV-2. Increased off-label use of ivermectin for COVID-19 has been reported.
Caroline S. Foo, Rana Abdelnabi, Laura Vangeel, Steven De Jonghe, Dirk Jochmans, Birgit Weynand, Johan Neyts   +6 more
doaj   +1 more source

Would ivermectin for malaria control be beneficial in onchocerciasis-endemic regions?

Infectious Diseases of Poverty, 2019
Background There is accumulating evidence supporting the use of ivermectin as a malaria control tool. Recent findings from the repeat ivermectin mass drug administrations for control of malaria trial demonstrated a reduced incidence of malaria in ...
Joseph Nelson Siewe Fodjo, Marina Kugler, An Hotterbeekx, Adam Hendy, Jean-Pierre Van Geertruyden, Robert Colebunders   +5 more
doaj   +1 more source

Ivermectin exposures reported to the Poisons Information Helpline in South Africa during the COVID-19 pandemic

South African Medical Journal, 2022
Background. Ivermectin is an antiparasitic drug that has shown in vitro activity against COVID‑19. Clinical studies supporting ivermectin for COVID‑19 prevention and treatment are conflicting, with important limitations. Public support for ivermectin is
V Pillay-Fuentes Lorente, G Voigt, C E du Plessis, K Balme, C J Marks, E H Decloedt, C Stephen, H Reuter, R van Rensburg   +8 more
doaj   +1 more source

Impact of ivermectin components on Anopheles dirus and Anopheles minimus mosquito survival

Parasites & Vectors
Background Ivermectin mass drug administration to humans or livestock is a potential vector control tool for malaria elimination. Racemic ivermectin is composed of two components, namely a major component (> 80%; ivermectin B1a), which has an ethyl group
Pattarapon Khemrattrakool, Thitipong Hongsuwong, Phornpimon Tipthara, Rattawan Kullasakboonsri, Theerawit Phanphoowong, Patchara Sriwichai, Borimas Hanboonkunupakarn, Podjanee Jittamala, Joel Tarning, Kevin C. Kobylinski   +9 more
doaj   +1 more source

Comparative effect of dose escalation of nanocapsulated ivermectin against mange in rabbits

German Journal of Veterinary Research, 2022
The present study aimed to investigate the effects of nano-capsulated ivermectin on the liver and kidney function and oxidative status in mite infested-rabbits, compared to ivermectin. Additionally, the ivermectin residue profile in adipose tissue, liver,
Azza Abdelmoteleb, Dalia Elmasry, Fatma Amro, Reham Mahmoud   +3 more
doaj   +1 more source

Integration of Nutrition and Organic Agriculture Framework in Managing Gastrointestinal Nematodes in Ruminants

Animal Research and One Health, EarlyView.
Gastrointestinal nematode infections damage the gastrointestinal epithelial tissues of ruminants, affecting nutrient utilization and overall production performance. This review outlines host‐gastrointestinal nematode interactions and discusses integrated control strategies, including nutritional supplementation, grazing management, vaccines, and ...
Wenxun Chen, Xiangfang Tang, Yimin Zhuang, Shengjun Zhao, Ying Ren, Xiaokang Lv   +5 more
wiley   +1 more source

Comparison between the efficacy of ivermectin and other drugs in treatment of cutaneous leishmaniasis [PDF]

Iraqi Journal of Veterinary Sciences, 2009
The study was conducted to compare the efficacy of ivermectin with some drugs in treatment of cutaneous leishmaniasis in vitro and in Balb/ C mice. The cultivation of Leishmania tropica was done on Nove MacNeal-Nicole medium (NNN).
M. A. Kadir, H. S. Aswad, A. M. Al-Samarai and G. A. Al-Mula
doaj   +1 more source

Parascaris spp. induced surgical colic in juvenile horses—A Scandinavian perspective

Equine Veterinary Journal, EarlyView.
Abstract Background Parascaris spp. commonly infects foals, and high burdens can cause fatal small intestinal impactions. Progressive anthelmintic resistance poses a risk for an increase of Parascaris spp. related disease in juvenile horses. Objectives To investigate Parascaris‐related surgical intestinal lesions, with special emphasis on ascarid ...
E. Tydén, I. R. Hellings, K. Toft Nielsen, A. Bergren, I. Holmgren, S. Attin, T. Pihl, A. Kendall, Y. Hedberg Alm   +8 more
wiley   +1 more source

Molecular mechanisms of Cys-loop ion channel receptor modulation by ivermectin

Frontiers in Molecular Neuroscience, 2012
Ivermectin is a gold standard anthelmintic drug that works by potently depressing neuronal activity and muscular contractility in arthropods and nematodes. At the molecular level, ivermectin activates inhibitory glutamate-gated chloride channels (GluClRs)
Timothy eLynagh, Joe eLynch
doaj   +1 more source