Results 11 to 20 of about 48,951 (258)
A five-day course of ivermectin for the treatment of COVID-19 may reduce the duration of illness
International Journal of Infectious Diseases, 2021 Ivermectin, a US Food and Drug Administration-approved anti-parasitic agent, was found to inhibit severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) replication in vitro.
Jyoti Somani +2 more
exaly +4 more sources
Ivermectin metabolites reduce Anopheles survival
Scientific Reports, 2023 Ivermectin mass drug administration to humans or livestock is a potential vector control tool for malaria elimination. The mosquito-lethal effect of ivermectin in clinical trials exceeds that predicted from in vitro laboratory experiments, suggesting ...
Kevin C. Kobylinski +14 more
doaj +2 more sources
Ivermectin Inhibits Stress Granule Clearance by Blocking the De Novo Synthesis of Hsp70 in Neuroblastoma Cells [PDF]
CellsCytoplasmic stress granules (SGs) form in response to diverse insults; they are dismantled when the stress subsides. SG clearance is facilitated by molecular chaperones, nuclear transport factors, and other components.
Siwei Chu +4 more
doaj +2 more sources
PLoS Pathogens, 2022 The antiparasitic drug ivermectin plays an essential role in human and animal health globally. However, ivermectin resistance is widespread in veterinary helminths and there are growing concerns of sub-optimal responses to treatment in related helminths ...
Roz Laing +12 more
doaj +2 more sources
Ivermectin in Acute Renal Injury Induced by Ischemia-Reperfusion: An Experimental Study in Wistar Rats [PDF]
Revista Brasileira de EnfermagemObjectives: to assess the effect of ivermectin in an experimental model of ischemia-reperfusion as a risk factor. Methods: twenty adult male Wistar rats were randomized into the following groups: Sham: surgical simulation without clamping of the renal ...
Raphael Cuencas Budini +6 more
doaj +5 more sources
Acute toxicity events of ivermectin in chicks’ model [PDF]
Iraqi Journal of Veterinary Sciences, 2022 Ivermectin is a very safe drug; however, there are many studies on its toxic effects in different animals due to sensitivity, misuse, or accidental overdose.
Tamara K. Al-Najmawi, Muna H. Al-Zubaidy
doaj +1 more source
Journal of the American Medical Association (JAMA), 2021 Importance Ivermectin is widely prescribed as a potential treatment for COVID-19 despite uncertainty about its clinical benefit. Objective To determine whether ivermectin is an efficacious treatment for mild COVID-19.
Eduardo López-Medina +18 more
semanticscholar +1 more source
Drug Resistance Assessment of Commonly Used Anthelmintics, and Their Combination Effect in Naturally Infected Sheep: The Case of Kaffa Zone, Southwestern Ethiopia. [PDF]
Vet Med SciThis study evaluated the efficacy of widely used commercial anthelmintics and examined whether combining different drug classes enhances their effectiveness in naturally infected sheep in the Kaffa Zone. This study suggest the presence of emerging anthelmintic resistance to albendazole and tetramisole in the study area and highlight the potential ...
Belay N, Arke A, Tesfaye L.
europepmc +2 more sources
Effect of Early Treatment with Ivermectin among Patients with Covid-19
New England Journal of Medicine, 2022 Background The efficacy of ivermectin in preventing hospitalization or extended observation in an emergency setting among outpatients with acutely symptomatic coronavirus disease 2019 (Covid-19), the disease caused by severe acute respiratory syndrome ...
Gilmar Reis +26 more
semanticscholar +1 more source
Journal of the American Medical Association (JAMA), 2023 Importance It is unknown whether ivermectin, with a maximum targeted dose of 600 μg/kg, shortens symptom duration or prevents hospitalization among outpatients with mild to moderate COVID-19.
S. Naggie +248 more
semanticscholar +1 more source