Potential value of triple drug therapy with ivermectin, diethylcarbamazine, and albendazole (IDA) to accelerate elimination of lymphatic filariasis and onchocerciasis in Africa [PDF]
, 2017 BACKGROUND: Strongyloides stercoralis is the only soil-transmitted helminth with the ability to replicate within its host, leading to long-lasting and potentially fatal infections. It is ubiquitous and its worldwide prevalence has recently been estimated
Fischer, Peter U +3 more
core +13 more sources
Human myiasis in Ecuador. [PDF]
, 2020 We review epidemiological and clinical data on human myiasis from Ecuador, based on data from the Ministry of Public Health (MPH) and a review of the available literature for clinical cases.
Calvopina, M +5 more
core +1 more source
Chromatographic Quantification of Ivermectin and Pranziquantel in the Tablets Using Stability Indicating RP-HPLC Method [PDF]
Pharmaceutical Sciences, 2019 Background: A new stability indicating RP-HPLC based assay method was developed to quantify ivermectin and praziquantel simultaneously and applied effectively to tablets.
Naga Venkata Suresh Kumar Devaka +1 more
doaj +1 more source
Asian Pacific Journal of Tropical Medicine, 2021 Objective: To evaluate different doses of ivermectin in adult patients with mild COVID-19 and to evaluate the effect of ivermectin on mortality and clinical consequences. Methods: A randomized, double-blind, placebo-controlled, multicenter clinical trial
Morteza Shakhsi Niaee +14 more
doaj +1 more source
PLoS Pathogens, 2022 The antiparasitic drug ivermectin plays an essential role in human and animal health globally. However, ivermectin resistance is widespread in veterinary helminths and there are growing concerns of sub-optimal responses to treatment in related helminths ...
Roz Laing +12 more
doaj +1 more source
Modelling the elimination of river blindness using long-term epidemiological and programmatic data from Mali and Senegal [PDF]
, 2017 The onchocerciasis transmission models EPIONCHO and ONCHOSIM have been independently developed and used to explore the feasibility of eliminating onchocerciasis from Africa with mass (annual or biannual) distribution of ivermectin within the timeframes ...
Basáñez, M-G +7 more
core +7 more sources
Update on the current status of onchocerciasis in Cote d’Ivoire following 40 years of intervention: Progress and challenges [PDF]
, 2018 Background Onchocerciasis control in Côte d’Ivoire started with aerial insecticide spraying in 1974 and continued with community directed treatment with ivermectin (CDTi) from 1992 to the present.
Aba, Elvis +10 more
core +4 more sources
Identification of the metabolites of ivermectin in humans
Pharmacology Research & Perspectives, 2021 Mass drug administration of ivermectin has been proposed as a possible malaria elimination tool. Ivermectin exhibits a mosquito‐lethal effect well beyond its biological half‐life, suggesting the presence of active slowly eliminated metabolites.
Phornpimon Tipthara +9 more
doaj +1 more source
Parasites & Vectors, 2023 Background The effects of ivermectin (endectocide) on mosquito survival make it a potential new malaria vector control tool. The drug can be administered to mosquito disease vectors through blood hosts that include humans and livestock. Its increased use
Caroline Kiuru +6 more
doaj +1 more source
Use of Ivermectin as a Potential Chemoprophylaxis for COVID-19 in Egypt: A Randomised Clinical Trial [PDF]
Journal of Clinical and Diagnostic Research, 2021 Introduction: The rate of secondary attacks of SARS-COV-2 is high among household close contacts. Social distancing, isolation and infection control measures are important for preventing exposure to infection, but insufficient.
Waheed M Shoumann +7 more
doaj +1 more source