Results 141 to 150 of about 49,496 (199)
New L‐Dopa Codrugs as Potential Antiparkinson Agents
AbstractThis paper reports the synthesis and preliminary evaluation of newL‐dopa (LD) conjugates (1and2) obtained by joining LD with two different natural antioxidants, caffeic acid and carnosine, respectively. The antioxidant efficacy of compounds1and2was assessed by evaluating plasmatic activities of superoxide dismutase (SOD) and glutathione ...
SOZIO, Piera+9 more
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REVERSAL OF SOME THERAPEUTIC EFFECTS OF AN ANTIPSYCHOTIC AGENT BY AN ANTIPARKINSONISM DRUG
Data are presented from a multidimensional, longitudinal study in 10 acute schizophrenics which indicate that the addition of benztropine to haloperidol reversed the course of some of the therapeutic changes. The nontherapeutic interaction was selective involving what may be called social avoidance behavior but not the cognitive integrative ...
Man Mohan Singh, James M. Smith
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Quantitative Determination of Some Synthetic Antiparkinsonism Agents
Nonaqueous titrimetry was employed to estimate quantitatively some of the compounds which are useful in treating Parkinsonism. The method was applied to both the crystalline material and their dosage forms. This technique was found to yield results which agreed well with those obtained by either the official procedures or by methods submitted by the ...
W.J. Racz, L.G. Chatten
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Efficacy of antiparkinson agents in preventing antipsychotic-induced extrapyramidal symptoms
The types of extrapyramidal syndrome (EPS) reactions produced by antipsychotic agents and the prophylactic use of antiparkinson agents in preventing EPS are reviewed. EPS are classified as akathisias, dystonias, parkinson-like symptoms and tardive dyskinesia, and have a varied incidence reported to range from 10.6 to 100%.
Ronald B. Stewart, John E. Murphy
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Potential antiparkinsonism agents. Quinuclidinyl benzhydryl ethers
Nilsson Jl, Wågermark J, Dahlbom R
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[Immunotropic activity of a potential antiparkinson agent himantane].
N-(Adamant-2-yl) hexamethyleneimine hydrochloride (A-7, himantane), a new potential antiparkinsonian drug belonging to the class of aminoadamantyl derivatives, exhibits pronounced immunomodulant activity in a therapeutic dose of 10 mg/kg. A single intraperitoneal injection of himantane stimulated a high B-lymphocyte activity in mice over a period of 21
G I, Nezhinskaia+3 more
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ANTIPARKINSON DRUGS AS CAUSAL AGENTS IN TARDIVE DYSKINESIA
Kiloh Lg, Williams Se, Smith Js
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Carotenoids as Antiparkinson Agents
2021Parkinson’s disease (PD) is a neurodegenerative disease associated with the loss of dopaminergic neurons in the portions of the brain via multiple pathological mechanisms. Despite the fact that enormous progress occurred in the cure of Parkinson’s disorder, but the incidence and risk of this disease is increasing alarmingly over the past few decades ...
Pratik Chakraborty+5 more
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POTENTIAL FOR ABUSE OF ANTIPARKINSON AGENTS
Psychiatric Services, 1982Hospital &‘ Community Psychiatrj is expanding its roster of peer reviewers for manuscripts submitted for publication. Professionals in the mental health disciplines who are qualified to serve as peer reviewers are invited to contact the editor. Reviewers must have significant publications in their specialty area, be abreast of the liteEature in that ...
Winston W. Shen, James Smith
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